The game is set in the distant future, where the world is ruled by intelligent animal - like forms that evolved from the machines responsible for the fall of an advanced human civilization centuries ago;
the former rulers of the world survived, but their lifestyle was reduced to that of primitive, isolated tribes.
The box sucks Wario in, and the
former ruler of that realm explains how an evil being sealed away his powers in the four different
worlds of the music box, each containing numerous stages.