Sentences with phrase «forming myofibroblasts»

The AHR ligands turned on AHR - dependent genes and blocked the TGFβ - driven transformation of human orbital fibroblasts to scar - forming myofibroblasts.
It was unknown which kinds of stem cells form myofibroblasts, and where these stem cells are located.

Not exact matches

Now they've discovered additional factors actually produced by the regenerating hair follicle to convert the surrounding myofibroblasts to regenerate as fat instead of forming a scar.
The most common cells found in healing wounds are myofibroblasts, which were thought to only form a scar.
The orbital remodeling in TED is likely induced by infiltrating T lymphocytes and mast cells, which activate orbital fibroblast effector cells to either proliferate and form scar - producing cells called myofibroblasts or turn into pro-inflammatory fat cells.
But heart cells never truly regenerate in the damaged tissue, and myofibroblasts compensate for their absence by forming a stiff, collagenous scar that interferes with the heart's ability to maintain stable heart rhythms and to expand and contract forcefully to pump blood.
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