Sentences with phrase «found more tumors»

Not exact matches

A new study, conducted by the U.S. National Toxicology Program, found that rats consistently exposed to radiofrequency radiation from cellphones were more likely to develop malignant tumors in the brain and heart.

They are finding cancerous tumors that are in phase 0 and 1 in patients who are experiencing no pain, whereas most people are often diagnosed in phase 4, where pain is prevalent and the disease is more difficult to beat.

The introduction of infant formula to babies» diets changes the infants» gut microbiome, thus affecting the response of the infant immune system to pathogens.47 - 51 A greater amount of natural - killer cells, suggesting a more mature immune system, have been found in breastfed infants than in formula - fed infants.52 In addition, pH level in the stomach of breastfed children is better for the promotion of the protein - lipid α - lactalbumin (termed HAMLET), which induces apoptosislike death in tumor cells.51, 53

«There was this initial thought that [circulating tumor cells] are only present at late stage,» says Sollier - Christen, but she notes that in the past year, several studies using more sensitive techniques have found such cells much earlier in tumor development, even before the tumor becomes visible by conventional imaging techniques.

Once they have consumed all the oxygen and nutrients in the original tumor site, the cancer cells travel to other parts of the body (metastasize) to find more nourishment.

Many more microchimeric cells are found in the blood of healthy women compared to those with breast cancer, for example, suggesting that microchimeric cells can somehow prevent tumor formation.

Earlier studies haven't found this to be the case, but they were plagued by self - selection: Women with more advanced tumors tend to avoid having babies, so those who did become pregnant may have had a better average prognosis.

Their analysis of more than 4,000 individual tumor cells, the largest effort to date in brain tumors, finds three developmental categories of cancer cells — one resembling neural stem cells and two characterized by sets of genes indicting paths towards differentiation.

With that knowledge, they screened more than four dozen monoclonal antibodies — unique agents that can stop cells from growing or forming tumors and can be mass produced — before finding two that block tumor creation in both types of cancer.

«As well as finding more effective treatments for advanced melanoma, we also need to stress the importance of early diagnosis, detecting tumors before they have a chance to spread.»

We found that the inflammation unfortunately gets hijacked by tumor cells that are able to grow faster and penetrate deeper because the blood vessels in the brain are more permeable than in any other part of the body.

Analyzing data from thousands of cancer lines and tumors, the researchers found that those demonstrating resistance to proteasome inhibitor drugs were marked by suppressed expression of one or more of the cells» proteasome cap subunits (which are a subsets of the larger proteasome).

They also found that more of the drug was available to attack tumor cells.

«Study identifies potential treatment target for pancreatic cancer: Molecular signature found in 30 percent of PDAC tumors associated with more aggressive cancer.»

More importantly, though, they found about a two-fold higher PD - L1 expression level for gastroesophageal cancers compared to right - side colon cancers but did not find such a marked difference between those tumors and SBAs.

«Finding which mechanisms determine why melanoma is so aggressive is very complex because more than 80,000 mutations have been described for this tumor,» says Direna - Alonso Curbelo, the article's first author.

Instead, researchers told the European Breast Cancer Conference that their findings suggest that extending screening programs to older women results in a large proportion of women being over-treated, and at risk from the harmful effects of such treatment, because these women were more likely to die from other causes than from any tumors detected in the early stages of growth.

Among cervical cancer survivors studied, colon, rectum and anus tumors were found to be two to four times more frequent in the group treated with radiation than in the group not treated with radiation.

A randomized phase III trial finding that a new monoclonal antibody, elotuzumab, added to standard therapy, extended the duration of remission for patients with relapsed multiple myeloma by about five months Findings from two phase III studies showing that children with Wilms tumor who have a specific chromosomal abnormality do better with a more intensive, augmented chemotherapy regimen

The team's recent study in mice has found that the treatment reduced the mass of ovarian cancer tumors and was more effective at suppressing tumor growth than chemotherapy.

A new investigation of more than 48,000 stored tumor samples finds evidence of a key deficiency in a repair mechanism designed to keep DNA from being mutated and causing cancer.

A more abundant and less invasive source of tumor DNA may be cell free tumor DNA found circulating in the blood.

But he found that the lab rats» diets had to be very rich in casein, at least 20 percent, to produce significantly more tumor growth, as opposed to Campbell's results of 10 percent.

The researchers then compared tumor cells isolated from multiple different breast cancer patients and found that cells expressing lower amounts of Numb - 1 and -2 were more resistant to the chemotherapy agent cisplatin.

Tumor cells use the unfolded protein response to alter circadian rhythm, which contributes to more tumor growth, Hollings Cancer Center researchers at the Medical University of South Carolina (MUSC) Tumor cells use the unfolded protein response to alter circadian rhythm, which contributes to more tumor growth, Hollings Cancer Center researchers at the Medical University of South Carolina (MUSC) tumor growth, Hollings Cancer Center researchers at the Medical University of South Carolina (MUSC) find.

Also, we know hormone receptive positive tumors are much more sensitive to radiation, which could explain why we found the survival benefit in this group of patients.»

The mean age of the K: B fusion population was 7.4 years old, compared to 15.2 years old in the non-K: B population; 73 percent of the K: B PAs were found in the cerebellum, whereas 78 percent of the non-K: B PAs were found elsewhere; and non-K: B PAs were much more likely associated with co-occurrence of the disease Type 1 Neurofibromatosis, which can lead to the formation of additional tumors.

Working in mouse models of primary, non-metastatic tumors, the researchers increased the production of the tRNAs, and found that these cells became much more invasive and metastatic.

«We found that many more mice developed tumors when given the cells that we had engineered to have these stem cell characteristics, and they had a much higher incidence of metastasis in the lungs,» Kilian said.

AFP reports that Israeli researchers found that frequent cell phone users — described as people who chatter on mobiles more than 22 hours a month — had a nearly 50 percent higher risk than others of developing a tumor on the parotid gland (the largest of the salivary glands on the side of the face just in front of the ear).

The researchers also found that when they delivered an antibody, IL - 2, and T cells targeted to the tumor, the adoptively transferred T cells killed cancer cells much more successfully than when only T cells were delivered.

Dozens of other studies have found that animals exposed to light at night develop tumors more readily than do those kept in the dark.

At Colchester General Hospital, the researchers looked at MR scans taken both before treatment and six weeks after the patients had completed chemotherapy and radiotherapy, and found that the patients whose tumors were less heterogeneous — ie more uniform — in terms of texture parameters six weeks after treatment were more likely to survive longer.

«This aspect of the research is one of the most intriguing findings to come out of the TCGA program, which has been looking at more than 30 tumor types over the past decade.»

«We found that the NFkB - Pim1 - Eomes axis, an important molecular mechanism that operates in memory T cells, could be enhanced with molecular or genetic strategies to help current vaccines or tumor therapies be more effective.

By shedding light on subtle distinctions in tumor biology, these findings offer clues to designing more effective anticancer treatments to precisely target tumors in individual patients.

«Both the person as a whole and the tumor itself will have had less time to accumulate mutations, so those that we do find are more likely to be relevant.»

The argument is augmented by a series of findings demonstrating that Malat1 is even more abundant than usual in some classes of malignant tumor cells.

«In addition to having a higher prevalence of triple - negative breast cancers than Caucasian women — something that has been documented in previous studies — we found that African American women with breast cancer had a significantly higher prevalence of the TP53 driver mutation, basal tumor subtype and greater genomic diversity within tumors, all of which suggest more aggressive tumor biology,» says Tanya Keenan, MD, of the MGH Cancer Center, lead author of the study.

In a study using mice, the researchers found that using Dox and TRAIL in the pseudo-platelet drug delivery system was significantly more effective against large tumors and circulating tumor cells than using Dox and TRAIL in a nano - gel delivery system without the platelet membrane.

After sequencing the tumor samples, the authors found that the JAK2 gene was more frequently amplified in chemotherapy - treated TNBC than in tumors before treatment.

«Potential pancreatic cancer target challenged: New research finds PDX1 critical for cancer growth, but blocking it may lead to more aggressive tumors.»

«This combination of features means that the drugs can not only attack the main tumor site, but are more likely to find and attach themselves to tumor cells circulating in the bloodstream — essentially attacking new tumors before they start,» says Quanyin Hu, lead author of the paper and a Ph.D. student in the joint biomedical engineering program.

They generated a list of suspected oncogenes and tumor suppressor genes based on their mutation patterns — and found many more potential cancer drivers than anticipated.

«If our findings are confirmed by additional studies, they may open doors to the development of targeted therapies against the tumor subtypes more likely to affect African Americans and potentially help reduce racial disparities in breast cancer.»

She also collected visceral fat tissue from women undergoing hysterectomies and found that when the fat secretions had more of the FGF2 protein, more of the cells formed cancerous tumors when transferred into mice.

«The apparent ability to change immunosuppressive T cells within the tumor into T cell types that are more active and potentially helpful against cancer was a really exciting finding, and one that we're continuing to investigate,» says Poznansky, who is an associate professor of Medicine at Harvard Medical School (HMS).

The human papillomavirus (HPV) causes genital warts and has been found in more than 90 % of cervical tumors.

The findings, which come thanks to new insights about how tumor cells communicate with their environment, may also bring physicians closer to the goal of more personalized medicine.

These findings show that MAX acts as a tumor suppressor gene in one of the more aggressive types of lung cancer.