When they examined the dinosaur's leg bone, they found ancient
fragments of a protein called collagen (KAHL - eh - jen).
Not exact matches
We now know that plaques are clusters
of protein fragments called beta - amyloid peptides.
The majority
of people in this field today believe that the plaques, made
of a
protein fragment called beta - amyloid peptide (BAP), come first, and that the accumulation
of this material causes the rest
of the disease.
A
protein fragment called amyloid - beta (Aβ) is known to aggregate and create plaque in the brains
of Alzheimer's patients.
The treatment uses tiny droplets
of fat,
called nanoliposomes, which are coated in
protein fragments that are able to stop amyloid
protein accumulating into plaques, even at low concentrations.
It binds to wall - building
protein fragments called peptides, in particular those that end with two copies
of the amino acid D - alanine (D - ala).
But rather than delivering the entire gene for the clotting - factor
proteins to cells, as most gene therapies do, the researchers used the viruses to engineer immune - regulating B cells to express a
fragment of the clotting factor fused to an immune molecule
called an immunoglobulin.
Specifically, the release
of a stress - coping hormone
called corticotropin - releasing factor (CRF), which is widely found in the brain and acts as a neurotransmitter / neuromodulator, is dysregulated in AD and is associated with impaired cognition and with detrimental changes in tau
protein and increased production
of amyloid - beta —
protein fragments that clump together and trigger the neurodegeneration characteristic
of AD.
Fibrin is an insoluble
protein produced by platelets (
fragments of white blood cells) from a soluble
protein called fibrinogen normally present in blood.
At the heart
of the «bit»
of memory is essentially a
fragment of DNA
called a promoter, which enables the machinery
of a cell to make a given
protein.
Now, researchers funded by the National Institute
of Biomedical Imaging Bioengineerng have developed a system to capture and identify a scarce blood peptide (a
fragment of an inflammatory
protein)
called P1 that can predict increased risk
of preterm birth.
Many neuroscientists believe that a buildup in the brain
of a
protein fragment called beta - amyloid causes Alzheimer's disease.
To detect this sort
of enzyme, the researchers designed nanoparticles coated with small
protein fragments called peptides that can be cleaved by particular proteases
called MMPs.
«The retraction states that Mignot and his colleagues were unable to replicate the results
of the ELISpot assay, a widely used method for measuring how immune system cells such as T cells respond to
fragments of foreign
proteins,
called antigens,» Underwood writes.
The researchers have identified the following mechanism: L. pneumophila establishes transient, highly dynamic contacts with host mitochondria and secretes an enzyme
called MitF that modifies the shape
of the mitochondria by inducing DNM1L (a host
protein that is necessary for
fragmenting mitochondria) depended mitochondrial fragmentation.
But in May, Schweitzer,
of North Carolina State University, replicated the results and also announced a bigger find: a collection
of even larger
protein fragments from an 80 - million - year - old duck - billed dinosaur
called Brachylophosaurus canadensis.
Vasculostatin is somewhat unique because it is a secreted
fragment of a membrane - bound
protein,
called BAI1.
A
fragment of one
of the
proteins that cancer cells use to exert the clotting effect,
called TFPI2, could be used to antagonize blood clotting  therapeutically, they write in Cancer Research. The findings could also have implications for understanding the effects of current medications, such as the angiogenesis inhibitor bevacizumab, also known as Avastin.
Beta amyloid is a
fragment of a
protein snipped from another
protein called amyloid precursor
protein (APP).
This visualization shows tightly - packed DNA in a mouse cell's nucleus at different stages
of development, seen here in a semi-triangular form as a mature nerve cell; in a roundish shape as a multipotent stem cell; in a more oval form as a neuronal progenitor; and as a more
fragmented structure that shows how removing a specialized binding
protein (HP1β knockout) affects the structure
of the DNA - packing material,
called heterochromatin, in a mature neuron.
In recent years, scientists made the surprising discovery that seminal fluid harbors
fragments of proteins that clump together, forming structures
called amyloid fibrils.
The approach developed by the MGH team starts with the engineered
protein, which in this case fuses an antibody
fragment targeting a
protein called mesothelin — expressed on the surface
of such tumors as mesothelioma, ovarian cancer and pancreatic cancer — to a
protein from the tuberculosis bacteria that stimulates the activity
of dendritic and other immune cells.
These pathogen bits, usually composed
of protein or
fragments or sugars, are
called «epitopes.»
In some cases, when fermentation changes the digestibility
of protein in soy foods (and in other foods as well), smaller
protein fragments are created (
called peptides) that have unique health supportive properties
of their own.
Some
proteins or
fragments of proteins are resistant to digestion and those that are not broken down in the digestive process are tagged by an antibody
called Immunoglobulin E (IgE).
These benefits are related to the presence
of small
protein fragments —
called peptides — that may get formed during the cooking process when
proteins in the tuna get broken down.