Beta amyloid plaques can form when particular
fragments of the amyloid precursor protein (APP), cleaved by the enzyme gamma secretase, clump together.
Not exact matches
In the brains
of patients with Alzheimer's disease (AD),
amyloid precursor protein is broken apart, and the resulting
fragments — β -
amyloid peptides, or Aβ peptides — aggregate to form plaques.
Our microscopy studies with quantitative co-localization analysis revealed the presence
of intraneuronal Aβ in transgenic rats, with an immunological signal that was clearly distinguished from that
of the
amyloid precursor protein (APP) and its C - terminal
fragments (CTFs).
Beta
amyloid is a
fragment of a
protein snipped from another
protein called
amyloid precursor protein (APP).