The resulting increase in
free amino acid concentrations activates the serine / threonine kinases, Akt1 and Akt2, which mobilize the signaling protein mTOR (the mammalian target of rapamycin), which then suppresses autophagic activity.
Not exact matches
Pedialyte or diluted Gatorade (though the low electrolyte
concentration here may become a concern) with added
free amino acids, such as glutamine (2 - 3 grams per 8 ounces of fluid).
This
amino acid is found in high
concentrations in a
free state within human blood.
Excessive autophagic destruction is avoided at night through a feedback mechanism that halts autophagic clearance when its products,
free amino acids, reach a sufficient
concentration.
As discussed by Robergs and Roberts [22],
amino acid catabolism during exercise is important for three reasons: 1) for
free energy during exercise to fuel muscle contraction; 2) to increase
concentrations of citric
acid cycle intermediates and therefore support carbohydrate and lipid catabolism; and 3) to serve as gluconeogenic precursors.