Sentences with phrase «free survival improvements»

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Equally, however, it has been the dramatic improvement in the survival rate of infants that for the first time has freed women from the social obligation for a lifetime producing and rearing babies.

The researchers discovered that patients who had certain genetic variations in interleukin genes had a better response to either surgery or chemotherapy, resulting in improvements in overall survival, disease - free survival and the amount of time until disease recurred.

In the trial, patients receiving all three drugs had a 35 percent improvement in progression - free survival — the length of time before the disease begins to worsen — compared to those receiving lenalidomide and dexamethasone alone.

For patients with cervical cancer that has recurred after treatment or has spread elsewhere in the body, adding the experimental drug cediranib to standard chemotherapy improves tumour shrinkage and adds a modest improvement in progression - free survival, researchers report at the ESMO 2014 Congress in Madrid.

«We didn't see an improvement in overall survival or a statistically significant increase in progression - free survival, as defined in the context of this trial,» says the study's senior author, Minesh P. Mehta, M.B., Ch.B., Professor of Radiation Oncology at the University of Maryland School of Medicine and a radiation oncologist at the University of Maryland Marlene and Stewart Greenebaum Cancer Center.

Helmut Oettle, M.D., Ph.D., of the Charite - Universitatsmedizin Berlin, Germany, and colleagues conducted follow - up of a randomized trial that previously reported improvement in disease - free survival with adjuvant (in addition to surgery) gemcitabine therapy to determine if this treatment improved overall survival.

Similarly, relapse - free survival for those receiving intraperitoneal chemo was 23.8 months compared with 18.3 months for the intravenous - alone group, a 20 percent improvement.

Although the Eastern Cooperative Oncology Group Trial EST 168430 demonstrated improvements in both disease - free and overall survival, subsequent studies31 have not shown interferon to have significant benefits in the management of patients with stage II or stage III metastatic melanoma.

John M. Kirkwood reports the first significant improvement of both survival and relapse - free interval for melanoma patients treated with high - dose Interferon alfa - 2b (E1684).

But, even the patients without either of those abnormalities had a modest improvement in progression - free survival with PARP inhibitors.

He concluded that the improvement in progression - free survival and potential for overall survival benefit should lead to a phase III trial of this therapy option in small - cell lung cancer.

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