Wu's team attempted to mimic the spongy, three - dimensional structure of
bone marrow, in which the stem cells mature anchored to scaffolding constructed
from cells known as
stromal cells.
Maria Rostovskaya (Stewart, TUD)-- «Lineage commitment of conditionally immortalized
bone marrow mesenchymal
stromal cells
from tetracycline - regulated SV40 large t - antigen transgenic mice» (2010)
Roberts, E. W. and Deonarine, A. and Jones, J. O. and Denton, A. E. and Feig, C. and Lyons, S. K. and Espeli, M. and Kraman, M. and McKenna, B. and Wells, R. J. B. and Zhao, Q. and Caballero, O. L. and Larder, R. and Coll, A. P. and O'Rahilly, S. and Brindle, K. M. and Teichmann, S. A. and Tuveson, D. A. and Fearon, D. T. (2013) Depletion of
stromal cells expressing fibroblast activation protein - alpha
from skeletal muscle and
bone marrow results in cachexia and anemia.