Not exact matches
All sexually reproducing organisms have pairs of
chromosomes in all body cells (
humans have 23
chromosome pairs), one
chromosome of each pair inherited
from the father and one
from the mother.
We saw, for example, that
human chromosome 2 was a fusion of two ancestral
chromosomes,
chromosomes that are still separate in chimpanzees, and we can even see the useless remnants of teleomeres and centromeres
from the ancestral
chromosomes.
It has all the attributes of a
human from the beginning, and those attributes were in the forty - six
chromosomes with which it began.
@NII YOU SOUND LIKE YOU ARE GUILTY AND TALKED ABOUT OTHER FALSEHOOD RELIGION YOU DID NOT LIKE OR UNDERSTAND WHEN YOU WAS LITTLE CHILD OR YOUNGER ADULT OR MID LIFE PERSON.THERE ARE THOUSANDS OF GLOBAL FALSEHOOD RELIGIONS.BUT THIS ONE THING DOES NOT LIE (DNA) Y
CHROMOSOME EVEN TOP SUPER SMART BLOND HEAD BLUE EYE PALE SKIN SUPER DNA RESEARCH PROFESSIONALS WITH MULTIPLE PHD DEGREES
FROM NORWAY SWEDEN AND FINLAND DENMARK ETC KNOW THAT THE Y
CHROMOSOME ALSO KNOWN AS THE ADAM Y
CHROMOSOME CAMED OUT OF EAST AFRICA.falsehood religion did not make.the
human race WISDOM DID WISDOM WALKED AND TALKED WITH MAN IT WAS WISDOM THAT MADE ADAM AND EVE.THINK ABOUT IT @NII NOW THE MOST DOMINANT DNA BELONGS TOO BLACK PEOPLE NOT EUROPEANS.LOOK AT ALL YOUR MIXED RACE BLACK PEOPLE»S TIGER WOOD»S HALLEY BERRY LENNY KRAVITZ LISA BONET ETC DNA DO NT LIE man made falsehood religion do lie
Science Why jump all the way forward
from 3.75 billion years to the
Human Y
Chromosome 3.5 billion years later?
Instead of using a piece of DNA that the researchers injected to repair cuts made by CRISPR / Cas9,
human embryos used their own DNA
from another
chromosome as a repair template.
Both mouse and
human males typically die early
from the mutation in Mecp2, because their Y
chromosome does not supply a normal copy of the gene.
(A successful derivation of stem cells
from a cloned
human embryo was not reported until October 2011, and these stem cells had three sets of
chromosomes rather than two.)
When the researchers compared the mRNA to a library of DNA sequences taken
from the dendrites of neurons by James Eberwine of the University of Pennsylvania Medical Center, they found that it came
from a single gene on
chromosome X — the
human version of which, when mutated, leads to fragile - X syndrome.
In fact, the so - called dinosaur DNA turned out to
from a
human Y
chromosome.
The sex
chromosomes lay the foundation for
human sexual difference, with women having two Xs, one
from each parent, while men get an X
from their mom and a Y
from their dad.
Panning for gold, the researchers examined cells
from human testes, where they guessed genes on the Y
chromosome should be particularly active.
In other news
from Bermuda: After comparing notes, researchers have concluded that
chromosome 22 will become the first
human chromosome to be completely sequenced, perhaps as early as fall.
In this study, researchers took cells
from patients with blood cancer MDS and turned them into stem cells to study the deletions of
human chromosome 7 often associated with this disease.
Local
human demographic history is inferred
from in - depth DNA sequence analysis of Sardinian men's Y
chromosomes.
The study involved Y
chromosomes obtained through the
Human Genome Diversity Project, and
from other sources.
However, to render such a comparison valid, the lab had to upgrade the
human X reference sequence, which was originally assembled as a mosaic of sequences
from the X
chromosomes of at least 16 people.
The evolution of
human populations has long been studied with unique sequences
from the nonrecombining, male - specific Y
chromosome (see the Perspective by Cann).
A drug that stops the HIV virus
from stitching itself into
human chromosomes is found to fight AIDS in an animal study.
Unlike
humans, who have two sets of
chromosomes (
from a mother and a father), the Upland cotton genome is configured with four sets, adding multiple layers of complexity for scientists such as Saski.
Even though Neandertals and modern
humans interbred several times in the past 100,000 years, the DNA on the Y
chromosome from a male Neandertal who lived at El Sidrón, Spain, 49,000 years ago has not been passed onto modern
humans, researchers report today in The American Journal of
Human Genetics.
«Like
humans, rust fungi contain two copies of each
chromosome, which makes their genetics much more complicated than other types of fungi,» said Assistant Professor Melania Figueroa
from the University of Minnesota.
In
humans, disorders like Down syndrome and some cancers result
from extra copies of
chromosomes.
Most detailed analysis yet of Y
chromosomes reveals how rapidly
humans split into three groups in Arabia after emerging
from Africa
In this configuration, the
chromosomes are ordered by length
from the largest (
chromosome 1) to the smallest (
chromosome 22 in
humans), followed by the sex
chromosomes.
Chromosomes come in two matching sets, one
from each parent, but the first
human genome sequences published in 2001 (one by Venter, the other by federally funded researchers) were pastiches of both sets
from several different individuals.
(Most
human cells normally have 46
chromosomes: two sets of 23, one set inherited
from each parent.)
It appears that for a
human embryo to develop it needs one or more genes
from the father in this region of
chromosome 15, and that without these genes it develops Prader - Willi syndrome.
They knew the
human genome was carved into 23 pairs of structures, called
chromosomes, made
from deoxyribonucleic acid, or DNA.
The Y
chromosome lineage will have a big impact on the emerging field of «archaeogenetics,» the reconstruction of
human history
from molecular genetics, says archaeologist Colin Renfrew of the McDonald Institute for Archeological Research in Cambridge, United Kingdom.
Analysis of DNA
from mitochondria, above, and
from the Y
chromosome helps track where modern
humans came
from.
Wray and his colleagues sequenced this regulatory region and some flanking DNA
from 74
human chromosomes as well as 32
chromosomes from seven other primates, including chimps, gorillas, and orangutans.
Chronic myelogenous leukemia (CML) is a
human disease associated with a consistent chromosomal translocation that results in sequences
from the c - abl locus on
chromosome 9 being fused to sequences in a breakpoint cluster region (bcr) on
chromosome 22.
In recent years, scientists all over the world have investigated the organisation of
chromosomes inside cells
from species ranging
from larger bacteria to
human.
We identified
human X-linked genes whose gametologs have been pseudogenized or completely lost
from the Y
chromosome and inferred which evolutionary forces may be acting to retain genes on the Y. Although gene loss appears to be largely correlated with the suppression of recombination, we observe that X-linked genes with functional Y homologs evolve under stronger purifying selection and are expressed at higher levels than X-linked genes with nonfunctional Y homologs.
Even though Neandertals and modern
humans interbred several times in the past 100,000 years, the DNA on the Y
chromosome from a male Neandertal who lived at El Sidrón, Spain, 49,000 years ago has not been passed onto modern
humans, researchers report.
They then derive a mutation for the
human Y
chromosome from the mutation rate estimated
from autosomal pedigree data.
In an effort to solve this problem, a team of scientists
from Israel and the United States have created a new type of cell that doesn't exist in nature —
human stem cells with only half of our naturally occurring
chromosomes.
Telomeres (in white) cap the ends of
human chromosomes, protecting the genetic information
from damage.
By using
human and chimpanzee Y
chromosomes as a genetic fossil record to examine our past, scientists have seen a surprising difference in the way the male - making
chromosomes from the two species...
Comparison of genes on the sex - determining X and Y
chromosomes indicates that the ancestor of
human sex
chromosomes first arose
from an identical pair of standard
chromosomes approximately 240 to 320...
«In fact, abnormal cells with numerical and / or structural anomalies of
chromosomes have been observed in as many as 80 - 90 % of
human early stage embryos following in vitro fertilization,» says Professor Thierry Voet
from the Wellcome Trust Sanger Institute, UK, and the University of Leuven, Belgium, another senior author of this paper, «and CSV tests may expose some degree of these abnormalities.»
Each
human has 46
chromosomes — 23
from his or her mother and 23
from his or her father.
The evidence emerged
from a linkage study of Icelandic families that showed that schizophrenia correlated with an area on the eighth of the 23 pairs of
human chromosomes.
A new study, looking at the sex - specifically inherited X
chromosome of prehistoric
human remains, shows that hardly any women took part in the extensive migration
from the Pontic - Caspian Steppe approximately 5,000 years ago.
SPECIES COMPARISON: This circular genome map shows shared genetic material between
humans (outer ring) and (
from inner ring outwards) chimpanzee, mouse, rat, dog, chicken, and zebrafish
chromosomes.
Methods: 34 binary markers and 17 short - tandem - repeat loci
from the non-recombining part of the
human Y
chromosome were analyzed by RFLP, Sequencing and Genescanning.
Abbreviations: Aβ, amyloid β - peptide; AD, Alzheimer's disease; ALS, amyotrophic lateral sclerosis; Ambra1, activating molecule in Beclin -1-regulated autophagy; AMPK, AMP - activated protein kinase; APP, amyloid precursor protein; AR, androgen receptor; Atg, autophagy - related; AV, autophagic vacuole; Bcl, B - cell lymphoma; BH3, Bcl - 2 homology 3; CaMKKβ, Ca2 + - dependent protein kinase kinase β; CHMP2B, charged multivesicular body protein 2B; CMA, chaperone - mediated autophagy; 2 ′ 5 ′ ddA, 2 ′, 5 ′ - dideoxyadenosine; deptor, DEP - domain containing mTOR - interacting protein; DRPLA, dentatorubral pallidoluysian atrophy; 4E - BP1, translation initiation factor 4E - binding protein - 1; Epac, exchange protein directly activated by cAMP; ER, endoplasmic reticulum; ERK1 / 2, extracellular - signal - regulated kinase 1/2; ESCRT, endosomal sorting complex required for transport; FAD, familial AD; FDA, U.S. Food and Drug Administration; FIP200, focal adhesion kinase family - interacting protein of 200 kDa; FoxO3, forkhead box O3; FTD, frontotemporal dementia; FTD3, FTD linked to
chromosome 3; GAP, GTPase - activating protein; GR, guanidine retinoid; GSK3, glycogen synthase kinase 3; HD, Huntington's disease; hiPSC,
human induced pluripotent stem cell; hVps, mammalian vacuolar protein sorting homologue; IKK, inhibitor of nuclear factor κB kinase; IMPase, inositol monophosphatase; IP3R, Ins (1,4,5) P3 receptor; I1R, imidazoline - 1 receptor; JNK1, c - Jun N - terminal kinase 1; LC3, light chain 3; LD, Lafora disease; L - NAME, NG - nitro - L - arginine methyl ester; LRRK2, leucine - rich repeat kinase 2; MIPS, myo - inositol -1-phosphate synthase; mLST8, mammalian lethal with SEC13 protein 8; MND, motor neuron disease; mTOR, mammalian target of rapamycin; mTORC, mTOR complex; MVB, multivesicular body; NAC, N - acetylcysteine; NBR1, neighbour of BRCA1 gene 1; NOS, nitric oxide synthase; p70S6K, ribosomal protein S6 kinase - 1; PD, Parkinson's disease; PDK1, phosphoinositide - dependent kinase 1; PE, phosphatidylethanolamine; PI3K, phosphoinositide 3 - kinase; PI3KC1a, class Ia PI3K; PI3KC3, class III PI3K; PI3KK, PI3K - related protein kinase; PINK1, PTEN - induced kinase 1; PKA, protein kinase A; PLC, phospholipase C; polyQ, polyglutamine; PS, presenilin; PTEN, phosphatase and tensin homologue deleted
from chromosome 10; Rag, Ras - related GTP - binding protein; raptor, regulatory - associated protein of mTOR; Rheb, Ras homologue enriched in brain; rictor, rapamycin - insensitive companion of mTOR; SBMA, spinobulbar muscular atrophy; SCA, spinocerebellar ataxia; SLC, solute carrier; SMER, small - molecule enhancer of rapamycin; SMIR, small - molecule inhibitor of rapamycin; SNARE, N - ethylmaleimide - sensitive factor - attachment protein receptor; SOD1, copper / zinc superoxide dismutase 1; TFEB, transcription factor EB; TOR, target of rapamycin; TSC, tuberous sclerosis complex; ULK1, UNC -51-like kinase 1; UVRAG, UV irradiation resistance - associated gene; VAMP, vesicle - associated membrane protein; v - ATPase, vacuolar H + - ATPase; Vps, vacuolar protein sorting
After a 3 — 7 days of aging at room temperature, the slide was hybridized with probes
from the SkyPaint ™ DNA kit for
human chromosomes (Applied Spectral Imaging, Vista, CA, USA, http://www.spectral-imaging.com) for 2 days in a 37 °C humidified chamber.
CEP8 - SA probe complementary to
human chromosome 8 - specific centromeric repetitive sequences and directly labeled with SpectrumAqua fluorophore was obtained
from Abbott Molecular, Inc. (Des Plaines, IL).