Although human studies are needed, promising
evidence from animal studies indicates that intermittent fasting may help prevent cancer (27, 28, 29, 30).
Most studies test drugs before pathology is present, which is preventive rather than therapeutic and may be the reason drugs don't
transfer from animal studies to humans.
The main take
away from animal studies is that there is further research to be done to really get to the bottom of this.
Building on promising
results from animal studies, they initiated a gold - standard clinical trial in older adults with cognitive complaints.
If you sign up to take part in a clinical trial, you can trust that scientists have solid
evidence from animal studies that the test drug might work, right?
Original evidence linking the opioid system to social processes comes
from animal studies of the drug morphine, which acts on a receptor in the opioid system, the µ - opioid receptor.
They also published findings
from an animal study showing that the effect of stem cell therapy following heart attack is indirect — the stem cells themselves do not survive long after being placed in the heart, but they cause enduring effects by stimulating the rapid growth of surviving heart tissue and attracting stem cells already in the heart, which mature into functional heart cells.
Simon Festing says that reducing publication bias in animal research would ensure a sound basis to
move from animal studies...
Although it is impossible to
generalize from animal studies to humans, we recommend that women who are pregnant (or considering pregnancy) consult with their healthcare providers if they are consuming or planning to consume flaxseeds in these high amounts.
«The aim is to see if the data gained
from animal studies for slowing aneurysm growth holds true for humans,» says Eliasion.
But based on other evidence —
largely from animal studies — the FDA expressed «some concern» about the potential effects of BPA on the brain, behavior, and prostate glands in fetuses, infants, and young children.
New evidence
from animal studies supported by the National Institute of Mental Health suggests that a specific gene may affect learned fearfulness.
Promising results
from animal studies targeting the liver, muscles and the brain suggest that the CRISPR genome - editing method could revolutionise medicine, allowing us to treat or even cure a huge range of disorders.
Campbell stumbled across statistics about osteoporosis in the 1980s when he took a
break from his animal studies to direct the China - Oxford - Cornell project, a massive investigation of diet and disease based on data gathered from 6,500 rural Chinese families.
But especially when it comes to low - dose exposure, it is often difficult to make a direct connection between evidence of
harm from animal studies (the source of most data) and the implications for human health, says Ann Yaktine, a researcher at the Institute of Medicine who has authored several papers on trade - offs between nutrition and contamination.
Studying early human development in the academic setting is extremely difficult, in part because of political constraints on embryo research in the United States, so a certain amount of our knowledge is limited to
inferences from animal studies.
Mounting evidence
from animal studies highlights the potential of antioxidants, compounds that protect cells from toxic reactive oxygen species, to accelerate either cancer growth or metastasis.
Thomas Insel, director of the National Institute of Mental Health, notes that the report is consistent with evidence not
only from animal studies but also from the fact that children with autism — who avoid social interactions — also show decreases in oxytocin.
Those studies are ongoing, but the common thread through all of that is we've finally managed to
bridge from the animal studies all the way to humans, and we're taking that into the clinic.
According to the research data
collected from animal studies it has a reported ability for boosting the levels of bioavailable testosterone and it also simulates the production of sperm.
Hypotheses
generated from animal studies that the endogenous opioid system is an important modulator of food intake suggest that blockade of the system in humans should affect eating behavior.
Although there is not an abundance of research on fasting in humans, a growing number of health experts believe that the results of
fasting from animal studies hold great promise for human health and future research efforts.
extensive evidence
from animal studies points to the importance of the hippocampus in the association between diet and mental and cognitive health
«While the pre-birth programming effect of PETN shows promise for future clinical implications, we must be careful about generalizing
findings from animal studies to humans,» Li said.
We
know from animal studies that GABA - A receptor activity seems to affect drinking patterns, whereas GABA - B receptors seem to be involved in overall desire for alcohol.
The paper goes on to point out that, «Evidence,
primarily from animal studies, suggests that the functional development of the auditory system is largely influenced by environmental acoustic inputs early in life.»
However, «taking into consideration the weight of evidence,» EFSA concluded that the epidemiological studies did not contradict the
conclusion from animal studies «that glyphosate is unlikely to pose a carcinogenic hazard to humans.»
It's allowed us to
move from animal studies to clinical trials within less than a year of the publication of the animal study, which, as far as I know, is unprecedented and extremely exciting.