Sentences with phrase «from available drugs»

They do so by combining or processing various ingredients to arrive at a formulation that best serve the need of the patient, which they couldn't get from the available drugs in the market.

In the Netherlands, based on research reported in 2016 in Science Translational Medicine, Clevers and colleagues are already using personalized gut organoids, derived from rectal biopsies, to test whether cystic fibrosis patients will benefit from available drugs.

Not exact matches

While the new mid-stage study results from DNDi were impressive (they showed cure rates of 96 % to 97 % even for the sickest patients and those with liver scarring), more late - stage trials will be necessary before the drug is available on a large scale in the developing world.

These risks and uncertainties include, among others: the unfavorable outcome of litigation, including so - called «Paragraph IV» litigation and other patent litigation, related to any of our products or products using our proprietary technologies, which may lead to competition from generic drug manufacturers; data from clinical trials may be interpreted by the FDA in different ways than we interpret it; the FDA may not agree with our regulatory approval strategies or components of our filings for our products, including our clinical trial designs, conduct and methodologies and, for ALKS 5461, evidence of efficacy and adequacy of bridging to buprenorphine; clinical development activities may not be completed on time or at all; the results of our clinical development activities may not be positive, or predictive of real - world results or of results in subsequent clinical trials; regulatory submissions may not occur or be submitted in a timely manner; the company and its licensees may not be able to continue to successfully commercialize their products; there may be a reduction in payment rate or reimbursement for the company's products or an increase in the company's financial obligations to governmental payers; the FDA or regulatory authorities outside the U.S. may make adverse decisions regarding the company's products; the company's products may prove difficult to manufacture, be precluded from commercialization by the proprietary rights of third parties, or have unintended side effects, adverse reactions or incidents of misuse; and those risks and uncertainties described under the heading «Risk Factors» in the company's most recent Annual Report on Form 10 - K and in subsequent filings made by the company with the U.S. Securities and Exchange Commission («SEC»), which are available on the SEC's website at www.sec.gov.

Phase I funding — which allows up to $ 250,000 for an academic idea, such as decoding the genetic sequence of a protein or studying targeted drug delivery by using magnetic nanoparticles — is available from federal funding and foundations.

CVS said it achieved this in part by excluding Valeant diabetes drug Glumetza from its standard formulary, or the list of drugs typically covered by insurance, because a generic version of the medication was available.

Drugmakers have benefitted from the surge of opioid - related deaths in the U.S.; last year, Bloomberg reported that the drug's price had risen tenfold in recent years, with state and local governments shelling out to make the med more widely available.

According to Living Goods, clients may also be reluctant to buy drugs from other private providers because of the risk of getting a counterfeit medicine.63 Living Goods sent us a study conducted at the midline of its RCT that claims that both availability of counterfeit drugs and drug prices decreased at private retailers in areas where CHPs worked.64 According to the study, about 37 % of private drug shops in the areas it studied sold fake ACT drugs, 65 and availabilty of fake ACTs was about 50 % lower among non-Living Goods sellers in the areas where Living Goods worked.66 Additional results on these potential effects will be made available when the full RCT is published.

As Business Insider notes, «Based on seven major illegal drug data surveillance systems, the researchers found that heroin, cocaine and marijuana became significantly cheaper and more potent from 1990 to 2007 (the last year for which data is publicly available).»

The Grocery Manufacturers Association (GMA) last week urged the Food and Drug Administration to ensure any proposed long - term sodium reduction targets are based on a review of the Dietary Reference Intake (DRI) for sodium, future knowledge gained from work on the short - term sodium reduction targets, results of new research that will become available on human health outcomes and dietary sodium intake, and the emergence of new technologies that allows sodium reduction targets to be safely and effectively achieved.

In this study, and in opposition to findings elsewhere, higher levels of social support were associated with greater depressive symptomatology, leading researchers to speculate that for low - income men the perceived costs of reciprocity may have deterred them from utilizing available support; or that peer groups may have influenced their alcohol or drug use, or placed demands on their resources (Anderson et al, 2005).

Excellent books and tables of drugs that are safe or contraindicated in breastfeeding are available to the physician for reference, including a publication from the AAP.55

Drugs cited in Tables 1 through 7 are listed in alphabetical order by generic name; brand names are available from the current Physicians» Desk Reference, 23 USP DI 2001: Drug Information for the Health Care Professional, Volume I, 24 and USP Dictionary of USAN and International Drug Names.25 The reference list is not inclusive of all articles published on the topic.

But of course you would still blame it on them because a hospital birth isn't what your EGO needed so you were forced to birth at home far away from the evil drugs that you might wish to take because they are readily available.

You were probably available because your real parents were: a) brainwashed, b) bullied, c) poor and offered no real assistance, d) drugged (single women have had their babies stolen by social workers while they were still medicated from childbirth), e) stolen some other way, f) some combination of the above, or g) all of the above.

This year, GE received approval from the U.S. Food and Drug Administration to make the SIGNA ™ Premier available for sale.

The plan is to make the drug — commonly known by the brand name Vivitrol — available to inmates, people enrolled in drug court programs and others, like those who might have been saved from an overdose.

This bill would make the treatment available for patients as soon as possible, if their condition is serious enough to merit treatment from the drug.

Responding to today's announcement from Health Secretary Alan Johnson MP on top - up funding for drugs not available on the NHS, the ABI's Director General, Stephen Haddrill, said:

Currently available drugs to treat HSV - 1 infection work by preventing the virus from producing the proteins it needs to replicate and are known as nucleoside analogs.

If the drug makes it through subsequent patient trials, it will be available for doctors to prescribe much sooner than a drug created from scratch.

The SMU researchers discovered the three hit compounds after virtually screening more than 15 million small drug - like compounds made publically available in digital form from the pharmacology database Zinc at the University of California, San Francisco.

An anxiety drug available in France protects mice from the virus

But, according to a report from the Paris - based charity Médicins du Monde, the generic drug would be available to 60 mostly low - income countries, and not to many middle - income countries with high HCV burdens.

Other experimental options include: — AVI - 7537, a drug designed to block viral protein from being made, has shown human tolerability in early studies and could have 100 courses available by early 2015.

«One of the great strengths of TSRI with its multidisciplinary, collaborative environment is that we can get started on researching these drugs even before the drugs are available in pure form from the ordinary scientific suppliers,» Taffe said.

In this collaboration, Dickerson designed the synthesis of drugs from precursor compounds prior to scheduling, when they are not available from research supply companies.

«Patients would profit especially since new drugs would be available faster and at lower prices,» comments Prof. Dr. Thomas D. Szucs from the European Center of Pharmaceutical Medicine at the University of Basel.

Cell transplantation as a treatment for diabetes is still essentially experimental, uses cells from cadavers, requires the use of powerful immunosuppressive drugs, and has been available to only a very small number of patients.

At the time of writing, just six had been approved by the US Food and Drug Administration for medical use (one other — Baltrodibin, adapted from the venom of the Lancehead snake — is not FDA approved, but is available outside the US for treatment of bleeding during operations).

Research like this, that's made publically available, will help speed up crucial advances in drug discovery to save more lives from cancer.»

In a Clinical Crossroads article featured in the March 6, 2013 issue of the Journal of the American Medical Association (JAMA), Dr. Dan Alford from Boston University School of Medicine (BUSM) and Boston Medical Center (BMC) suggests that prescription opioid abuse can be minimized by monitoring patients closely for harm by using urine drug testing (UDT), pill counts, and reviewing prescription drug monitoring program data when available.

«There are currently no drug therapies available that improve the very limited natural recovery from spinal cord injuries that patients experience,» said Lyn Jakeman, Ph.D., a program director at the NIH's National Institute of Neurological Disorders and Stroke, Bethesda, MD. «This is a great step towards identifying a novel agent for helping people recover.»

The dual - drug combination will likely cost even more, which has prompted outrage from physicians and patient advocates alike, as well as plans from insurers to ration the combination when it becomes commercially available.

A total of 19 name - brand drugs with data available from all four surveys were selected for final analysis and grouped by treatment indication: acne and rosacea; psoriasis; topical corticosteroids; antiinfectives; and antineoplastics.

This approach, however, differs from liquid biopsies, including commercial tests, which only profile a relatively small portion of the genome in patients already diagnosed with cancer for the purpose of helping monitor the disease or detect actionable alterations that can be matched to available drugs or clinical trials.

Doctors, clinic staff and pharmacists, Malani says, can help patients identify options from drug companies that might reduce costs by reducing copayments or overall price, and recommend generic equivalents when available.

By making TB drugs more widely available, the programme has largely reached its 2015 goals, halving the death rate from the disease, and cutting global case numbers by 5 per cent.

The three classes of antifungal drugs currently available — azoles, polyenes, and echinocandins — are far from optimal.

The study, published in the newest special issue of Journal of Psychoactive Drugs, was mentioned in a presentation on the topic of medical marijuana to the New Mexico Legislative Health & Human Services Committee last November, and is now available from Routledge Journals with Free Access.

Drug therapy was widely available when he fell ill, and although he still hears voices from time to time, he has done well.

Cases were considered certain if, having declared RA, they had taken a RA specific medication (methotrexate, leflunomide or a biologic) since 2004 (the period from which drug reimbursement data was available).

«Results lend support to current national initiatives from the National Academies, White House, and bipartisan legislation requesting that the U.S. Food and Drug Administration create a new regulatory classification for hearing devices meeting appropriate specifications to be available over the counter,» the authors write.

No drugs are currently available to mimic a lack of this protein, although the researchers are using a grant from the Cancer Prevention and Research Institute of Texas (CPRIT) to search for one.

Known as a COX - 2 inhibitor, Bextra belongs to the same class of drugs as rofecoxib (Vioxx), which manufacturer Merck yanked from pharmacy shelves last September after safety risks appeared (SN: 10/30/04, p. 286: Available to subscribers at COX - 2 inhibitor pulled off market.).

We offer the most comprehensive, integrated portfolio of drug development products and services available from a single global provider.

The process they have followed in order to gather the specific information was to extract from the published literature all pharmacogenomic biomarkers that relate to the US Food and Drug Administration (FDA) and the European Medicines Agency (EMA) approved drugs with pharmacogenomic information in their label and make them available in a database that triangulates between drugs, genes and pharmacogenomics biomarkers.

There are very few details available for GS - 5734 at the moment but it appears to be the same sort of drug as Favipiravir, the Japanese Ebola drug that was shown to protect people from the disease.

This framework will be built upon available open - source deep learning platforms that can be adapted to address different aspects of the cancer process as represented by JDACS4C's challenge topics: 1) understand the molecular basis of key protein interactions; 2) develop predictive models for drug response; and 3) automate the extraction and analysis of information from millions of cancer patient records to determine optimal cancer treatment strategies.

Guidance from an innovative computational approach could speed up the process and cut down the cost of new drug development, researchers from the University of Chicago Medical Center and Columbia University suggest in a study to be published in the February 2008 issue of Genome Research, available early online.