Sentences with phrase «from bone»

The protein was garnered from a bone buried nearly 20 metres down.

«One of the major limitations we see in treating blood cancers is the failure to clear cancer cells from the bone marrow,» said Flavia Pernasetti, PhD, of Pfizer Oncology Research and Development.

«We get almost all lineages of blood cells that you would expect from bone marrow.»

The finding of individuals at chick or near fledging stage (known from their bone surface texture) shows that Hakawai melvillei was breeding in New Zealand and was not migratory, unlike many birds of this group today.

«Our new approach takes young and aggressive macrophages from the bone marrow of a human donor and removes a key safeguard that cancer cells have co-opted to prevent them from being engulfed,» Alvey said.

But when they sit or lie down again, the material does not expand fully to its original shape, so it gradually loosens and breaks away from the bone.

Institute director Catherine Verfaille and her team pulled multipotent adult progenitor cells, referred to as MAPCs (and pronounced map - seas), from the bone marrow of mice and rats.

According to cardiologist Stefanie Dimmler at the University of Frankfurt in Germany, degraded telomeres might cause heart disease by impeding the ability of cells from the bone marrow to repair damaged parts of the arterial walls.

The study revealed that MSCs isolated from the bone marrow of patients with elevated bone marrow metal concentrations had lost the ability to differentiate into bone - forming osteoblasts.

They reworked procedures for extracting would - be proteins from the bone, identified protein fragments with a more sensitive mass spectrometer, and compared the recovered protein sequences to those from many more living animals.

She and her colleagues then collected stem cells from the bone marrow of drowsy and of well - rested mice and injected them into 12 mice that had received what would normally be a lethal dose of radiation.

The five - holed instrument — carved from the bone of a griffon vulture — might be capable of expressing greater harmonic variety than the modern - day flute, he says.

Charlotte Oskam and Michael Bunce of Murdoch University in Perth, Western Australia, who isolated the DNA, say researchers (including themselves) were using techniques designed to extract DNA from bone, not eggshells.

Those found in fat, for example, though relatively plentiful and easy to extract, do not seem to form cartilage as readily as those that come from bone marrow, Tuan says.

Extracting DNA from bone involves sucking out the calcium in the bone, says Bunce.

The doctors» plan was to kill off Brown's cancer - producing bone marrow cells with intensive chemotherapy and replace them with stem cells from the bone marrow of a healthy donor.

Until recently, it was impossible to distinguish the helpful macrophages that reside in the heart from the harmful ones that arrive from the bone marrow.

Weirder still, a woman could conceivably use sperm made from her bone marrow to inseminate her own eggs.

Macrophages without CCR2 originate in the heart; those with CCR2 come from the bone marrow, the research showed.

Most of the time when the heart is injured, these beneficial immune cells are supplanted by immune cells from the bone marrow, which are spurred to converge in the heart and cause inflammation that leads to further damage.

«When we did that, we found that the macrophages from the bone marrow did not come in,» Lavine said.

With a bit of persuasion they can be transformed into pluripotent stem cells capable of developing into all manner of tissues, from bone to blood to brain.

The cross-disciplinary research team identified a protein derived from bone marrow that has the ability to activate stem cells — the cells that are the most responsive to gene editing.

For example, they produce proteins called cytokines that tell infection - fighting immune cells to back off and recruit «suppressor» cells directly from the bone marrow that help cancel the immune attack.

(The cells would be obtained by giving the workers a drug that nudges blood stem cells from the bone marrow into the bloodstream, then hooking them to a machine that filters out the stem cells.)

Flow cytometry analysis using mouse blood showed that MSCs were released from bone marrow to the blood in cinnamtannin B -1-administered mice.

From the bone features, as well as its thickness and proportions, the team's paleontologist, Julia Clarke of the University of Texas, was able to determine the evolutionary relationships of the new birds as well as characteristics that indicate whether it likely was able to fly or dive.

• A Yale research team led by Diane Krause turned a single stem cell from the bone marrow of an adult mouse into lung, liver, intestinal, and skin cells for other mice.

The stem cells used to treat Paizley, specific to the blood, came from the bone marrow of a healthy adult donor.

The study developed a new in vitro system made from bone marrow stem cells and studied what would happen if its ambient temperature fell below 37 °C (the natural temperature of the human body).

At the back of the first chamber, Moyes leads me to a thick stone wall made from bone - hued rocks and chunks of speleothem.

Trapnell and Suzuki were prompted to test the novel macrophage transplantation therapy by studies showing that resident macrophage populations (such as those residing in the lung) can self - maintain without the cells having to regenerate directly from the bone marrow.

The researchers drew on data from the Bone Mineral Density in Childhood Study (BMDCS), funded by the NIH.

One single stem cell from the bone marrow is not going to be able to treat disorders as different as Alzheimer's disease and rheumatoid arthritis,» he says.

As part of the new study, researchers deleted CXCL12 production specifically from bone marrow vasculature in leukemic mice.

miR - 34a could have an additional therapeutic application, offering protection from bone metastases in a variety of cancers, Dr. Wan noted.

DNA extracted from the bone belongs to a mysterious ancient hominin that last shared an ancestor with our species and Neanderthals about a million years ago.

Deletion of the CXCR4 gene led to sustained T - ALL remission within a month in similar mice, as well as movement of the cancerous blood cells away from the bone marrow.

The 2009 specimen turns out to be a juvenile, just under a year old, judging from its bone growth, and it shows signs of having been coated in fuzz that was plastered against its body after death.

Although milk's calcium and other nutrients do promote bone growth, other substances in dairy foods — certain proteins and especially sodium — actually leach calcium from bone.

The researchers used a new cell tracing method to follow the movement of peritubular macrophages from the bone marrow to the testes.

But getting a DNA sample from a bone means drilling a hole in it, and archaeologists were not about to let geneticists go to work on the deteriorating human skeletons without some guarantee of a genome.

Once Katlyn arrived in May 2007, Candotti and his team removed stem cells from her bone marrow and exposed them to the engineered retrovirus, creating a human - virus hybrid.

Damage occurs when metastatic tumor cells recruit pre-osteoclast cells to the bone and then induce their differentiation into mature bone - degrading cells, which results in the release of proteins from the bone matrix that promote tumor cell growth.

Incorporating stresses from bone curves put the bone under about 1.4 times more stress than it would experience if the bones were considered to be simple straight beams, the researchers report online today in the Journal of the Royal Society Interface.

The shark will bite off the limb and spiral down to shred the flesh from the bone.»

Instead of using white blood cells, the British researchers, working with a Dutch group, want to take stem cells from bone marrow and insert the ADA gene into these.

Studying mouse monocytes in more detail, the researchers found that the increase in TNF levels that occurs with age causes premature release of immature monocytes from the bone marrow into the blood stream.

A few studies showed that stem cells from bone marrow could create scar tissue.

Tufts University biomedical engineers recently published the first report of a promising new way to induce human mesenchymal stem cells (or hMSCs, which are derived from bone marrow) to differentiate into neuron - like cells: treating them with exosomes.