Not exact matches
Diabetes researchers are considering various
replacements for insulin injections: Transplanting new pancreatic islet
cells that make insulin, coaxing the patient's own islets to regenerate, or treating diabetics early in the disease with immune - suppressing
therapies to prevent their body
from destroying the rest of their pancreatic islets.
HSCT is effectively used today as a form of «
replacement»
therapy for patients with hard - to - treat blood cancers, providing healthy
cells from either the patient (autologous transplantation) or
from a donor (allogeneic transplantation) to better equip patients to fight the disease on their own.
But for
cell replacement therapy to realize its potential, I anticipate that scientists must solve the developmental code, the set of rules that govern the formation of tissues, organs, and beings
from the original single
cell — the zygote.
«Skeletal muscle created
from stem
cells: Discovery is major step towards a stem
cell replacement therapy for Duchenne Muscular Dystrophy.»
Cell therapy, as envisaged by the teams of I - Stem, is primarily based on the identification of experimental protocols that can specifically guide differentiation of pluripotent cells to a cell fate, which presents a interest for the replacement of the defective cell population from the patient (the striatal neurons for Huntington's disease, the cells of the retinal pigment epithelium for retinitis pigmentosa, keratinocytes for genodermatoses, et
Cell therapy, as envisaged by the teams of I - Stem, is primarily based on the identification of experimental protocols that can specifically guide differentiation of pluripotent
cells to a
cell fate, which presents a interest for the replacement of the defective cell population from the patient (the striatal neurons for Huntington's disease, the cells of the retinal pigment epithelium for retinitis pigmentosa, keratinocytes for genodermatoses, et
cell fate, which presents a interest for the
replacement of the defective
cell population from the patient (the striatal neurons for Huntington's disease, the cells of the retinal pigment epithelium for retinitis pigmentosa, keratinocytes for genodermatoses, et
cell population
from the patient (the striatal neurons for Huntington's disease, the
cells of the retinal pigment epithelium for retinitis pigmentosa, keratinocytes for genodermatoses, etc.).
Scientists publishing in the journal
Cell Stem
Cell have reported the production of functional human oocytes
from discarded genetic material, a process which they suggest could one day assist in fertility treatment or mitochondrial
replacement therapy.
There are now multiple immunotherapies targeting clearance of alpha - synuclein
from the brain in early - stage clinical trials, and multiple trials underway or in the works on the next generation of
cell replacement therapies for dopaminergic neurons, including the TRANSEURO trial; the Summit4StemCell initiative, put together by Jeanne Loring — a researcher at The Scripps Research Institute who is exceptionally engaged with turning her research into
therapies; a Japanese trial to be run by Jun Takahashi of Kyoto University in Japan (cf. here and here); and a trial centered at Memorial Sloan Kettering Cancer Center headed by
cell biologist Lorenz Studer.
In addition, we use our expertise to facilitate the development of functionally mature beta
cells from embryonic stem
cells for
cell replacement therapies of type 1 diabetes.
San Diego, January 8, 2015 — ViaCyte, Inc., a privately - held regenerative medicine company with the first stem
cell - derived islet
replacement therapy for the treatment of diabetes in clinical trials, has received a No Objection Letter
from Health Canada providing clearance to proceed with sites in Canada for the Company's Phase 1/2 clinical trial of its VC - 01TM product candidate.