Sentences with phrase «from cells in a dish»

These synthetic ubiquitin variants act quickly, completely eliminating MERS from cells in a dish within 24 hours.

Not exact matches

A cell in my brain is different from a cell not in my brain but, say, in a culture of cells in a dish.

Extracts from this garlic even protected cells in a laboratory dish from certain types of damage.13 This isn't really surprising when you consider the nutritional changes that typically occur in plants when they sprout.

To develop their «disease in a dish» model, the team took skin cells from patients with Allan - Herndon - Dudley syndrome and reprogrammed them into induced pluripotent stem cells, which then can be developed into any type of tissue in the body.

The cells rose from the bottom of the dish in response to the magnet and clumped together at the interface between the gel and the air.

Furthermore, when healthy neurons in a dish were treated with serum from the patients and antibodies against leiomodin - 1, they did not survive, but removing the antibodies increased brain cell survival.

After 381 days, this cow's antibodies prevented 96 percent of the 117 HIV types from infecting cells in a lab dish.

These techniques include: human tissue created by reprogramming cells from people with the relevant disease (dubbed «patient in a dish»); «body on a chip» devices, where human tissue samples on a silicon chip are linked by a circulating blood substitute; many computer modelling approaches, such as virtual organs, virtual patients and virtual clinical trials; and microdosing studies, where tiny doses of drugs given to volunteers allow scientists to study their metabolism in humans, safely and with unsurpassed accuracy.

In addition to looking at mouse models of diabetes, the researchers also showed that exposure of human pancreatic islet cells — both from healthy donors and from patients with Type 1 diabetes — to fasting - mimicking diet in a dish stimulated insulin productioIn addition to looking at mouse models of diabetes, the researchers also showed that exposure of human pancreatic islet cells — both from healthy donors and from patients with Type 1 diabetes — to fasting - mimicking diet in a dish stimulated insulin productioin a dish stimulated insulin production.

In addition to helping understand disease by providing more powerful study models, «what this technology would allow you to do is reprogram a skin cell, for example, from a Parkinson's patient... into a pluripotent cell and then in a petri dish redirect that cell into... a neuron» to treat that patienIn addition to helping understand disease by providing more powerful study models, «what this technology would allow you to do is reprogram a skin cell, for example, from a Parkinson's patient... into a pluripotent cell and then in a petri dish redirect that cell into... a neuron» to treat that patienin a petri dish redirect that cell into... a neuron» to treat that patient.

Avivi's team has found out that fibroblast skin cells from the armpits of the rats can kill human cancer cells in a dish.

We've also found that in a petri dish, the anti-quorum-sensing molecule prevents Pseudomonas from killing human lung cells and from making a biofilm that would enable it to mount an attack.

Scientists have previously shown that isolated germline stem cells from mice can turn into eggs in a petri dish.

«What we really need to make this work is being able to go from iPS cells to sperm in a dish,» says Turner.

Next, the research team will examine specifically whether these liver cells obtained from human embryonic stem cells in a dish help repair injured livers in preclinical animal models of liver disease.

For his prototype he is growing mouse muscle from stem cells in a petri dish.

Zheng, together with Leah Boyer, then a researcher in Gage's lab and now director of Salk's Stem Cell Core, generated diseased neurons by taking skin cells from patients with Leigh syndrome, reprogramming them into stem cells in culture and then coaxing them to develop into brain cells in a dish.

The disease model, described in a new study by a UC San Francisco - led team, involves taking skin cells from patients with the bone disease, reprogramming them in a lab dish to their embryonic state, and deriving stem cells from them.

During her postdoctoral work, Bissell noticed that removing mammary cells from a mouse and putting them into a culture dish caused them to lose not only their normal in vivo shapes, but also their ability to secrete milk.

Developing safe and effective therapies for conditions such as peripheral nerve disorders requires the ability to take investigations from cells in a petri dish to patients in a clinic.

The new «tumor in a dish» method begins by taking the cancerous tissue removed during surgery or biopsy, cutting it up into small pieces and putting them in a special collagen gel that maintains them as «organoids» that retain the three - dimensional structure of the original tumor and include supporting cells from the tumor's environment.

According to his unpublished findings, when he puts glioblastoma cells from patients into lab dishes with brain organoids, the cells attach to the surface of the organoids, burrow into them, and within 24 to 48 hours grow into a mass that eventually «looks exactly like what happened in the patient's own brain,» Fine said.

But when dermal papilla cells from humans are put into dishes in the lab, they lose their ability to induce the formation of new follicles.

In cells grown on flat culture dishes, the expression of thousands of genes didn't match up with their normal patterns, explaining why the cells from those dishes had been unable to generate new hair follicles.

Rather than stick the isolated cells on a flat culture dish, they mixed the cells with liquid, then let the mixture hang in tiny droplets from a plastic lid, like condensation on the roof of a container.

Adoptive cell transfer procedures are mimicking exactly this process in a culture dish by taking T cells from patients, multiplying them, sometimes genetically modifying them, and then returning them to patients so that they can, for example, locate and kill cancer cells.

«Alzheimer's in a dish: Stem cells from patients offer model and drug - discovery platform for early onset form of disease.»

When human stem cells develop into beta cells in a dish, they only reach a precursor stage, unable to fully mature; this prevents them from effectively producing insulin in response to glucose.

Compounds from grapes may kill colon cancer stem cells both in a petri dish and in mice, according to a team of researchers.

The test procedure is performed on an in vitro skin model built at Fraunhofer IGB from human skin cells in special culture dishes.

The researchers report they were able to transform about one in 5,000 cells — enough to get several iPS cells from a single culture dish — and then coax them to become nerve cells or heart tissue on the benchtop.

Part of the issue was settled when Cecilia Riquelme, a postdoc in Leinwand's lab, drew blood from recently fed pythons and applied it to a dish of living rat heart cells.

Building on previous work from Yuan's lab showing that the activity of RIPK1 could be blocked by a chemical called necrostatin - 1, the research team tested how ALS cells in lab dishes would respond to the same treatment.

Researchers took cells from leaves of the most productive trees and grew them in a lab dish to produce cloned seedlings.

So instead of studying the whole animals, he began isolating single nerve cells from the mole rats and investigating them in lab dishes to track the molecular basis of the rodent's pain insensitivity.

In BRIC 17 - 1, cell cultures derived from thale cress plants are grown in Petri dishes and later examined to determine which genes are involved in certain cellular changeIn BRIC 17 - 1, cell cultures derived from thale cress plants are grown in Petri dishes and later examined to determine which genes are involved in certain cellular changein Petri dishes and later examined to determine which genes are involved in certain cellular changein certain cellular changes.

A team of developmental biologists led by Hans Schöler and Karen Hübner at the University of Pennsylvania placed densely packed clusters of stem cells from mouse embryos in a petri dish, using fetal calf serum as a growth medium and adding a gene protein that turns green when germ cells form.

The researchers are the first to grow human vaginal skin cells in a dish in a manner that creates surfaces that support colonization by the complex good and bad communities of bacteria collected from women during routine gynecological exams.

The researchers isolated tumor cells from patients and grew them to reproduce small tumors in the lab dish.

The researchers, led by University of California, San Diego neuroscientist Mark Tuszynski, took skin cells from the patients, grew them up in a culture dish and genetically engineered them to make human nerve growth factor (NGF).

Further testing in the laboratory dish showed that hematopoietic stem cells from the sleep - deprived mice responded less strongly than their peers to naturally occurring chemical signals that trigger cellular migration.

A key difference, however, is that Dolly's donor cell came from adult udder cells growing in lab dishes (see ScienceNOW, 24 February), while the donor cells used to create the monkey clones came from early embryos.

When pancreas cells containing clumps of misfolded IAPP, taken from an engineered diabetic mouse, were mixed in a dish of healthy human pancreas cells, it triggered the clumping of IAPP in the human cells.

Barbara Beltz of Wellesley College in Massachusetts knew from Petri dish experiments that crayfish blood cells — haemocytes — are attracted to the niche.

In this case, the researchers used samples from juveniles and adults with Fragile X syndrome and induced the cells to become neurons in a lab disIn this case, the researchers used samples from juveniles and adults with Fragile X syndrome and induced the cells to become neurons in a lab disin a lab dish.

«The blood - brain barrier forms pretty early in gestation, so the thyroid hormone, even from the mother, is probably not getting through the barrier and into the brain, likely leading to developmental deficits,» says Shusta, whose group was among the first to develop blood - brain barriers from patient - derived stem cells in the lab dish.

While testing that idea, the researchers noticed something peculiar about cancerous cells that had been removed from leukemia patients and were growing in lab dishes.

In lab dishes, Liu's team corrected a mutation in human cells from a patient with an iron - storage blood disorder called hereditary hemochromatosiIn lab dishes, Liu's team corrected a mutation in human cells from a patient with an iron - storage blood disorder called hereditary hemochromatosiin human cells from a patient with an iron - storage blood disorder called hereditary hemochromatosis.

The newfound protein might eventually help patients who suffer from the untreatable prion diseases: When the group mixed their artificial protein fragment with a fragment of the PrP protein that usually kills neurons in petri dishes, the mixture killed only half as many cells as the prion fragment alone.

The researchers then extracted stem cells from the embryos and grew the cells in dishes in the lab.