Not exact matches
In 1980 Fiers first sequenced the gene for hemagglutinin derived
from the human influenza
strain H3N2 that
circulated in 1965.
«There were a couple of these in the vaccine
strain the past two seasons that wound up making it a little bit different
from the actual
circulating virus
strain.»
The study also confirms that the «H1» hemagluttinin protein of the new virus derives
from the classical swine H1N1
strain, which shares a close common ancestor with the human H1N1
strain circulating before 1957 and several lines of evidence show that older people exposed to that virus may have some immunity to the new H1N1.
The authors confirm that the new
strain is comprised of segments
from swine flu
strains known to
circulate in Europe, Asia and North America, but that this combination has not previously been seen and appears to have been evolving independently
from its parent
strains for some time.
They tested a
strain of Zika virus currently
circulating in human populations in the Americas and another
from Africa, which is the original
strain identified in 1947.
«It was not known whether any of these vaccines could provide protection against the new outbreak West African Makona
strain of Ebola Zaire currently
circulating in Guinea,» said John Eldridge, Chief Scientific Officer - Vaccines at Profectus Biosciences, Inc. «Our findings show that our candidate vaccines provided complete, single dose protection
from a lethal amount of the Makona
strain of Ebola virus.»
In this case, researchers
from the Icahn School of Medicine at Mount Sinai in New York City took tops
from two flu
strains that
circulate only in birds, and connected each one to a human hemagglutinin stalk.
The researchers are taking hemagglutinin mutations
from every flu
strain that has ever
circulated, dumping them into a kind of scientific blender and attaching them to particles that can form the basis of a vaccine.
For the new study, researchers in Diamond's laboratory, led by first author Helen Lazear, PhD, now at the University of North Carolina at Chapel Hill, tested five
strains of the Zika virus in the mice: the original
strain acquired
from Uganda in 1947; three
strains that
circulated in Senegal in the 1980s; and the French Polynesian
strain, which caused infections in 2013 and is nearly identical to the
strain causing the current outbreak.
«Most of what we know about Enterococcus comes
from the few
strains circulating in the hospital,» says Lebreton.
The findings, which appear in the March 11 issue of Cell Host & Microbe, contradict previous reports
from Indian health officials that the
strain has not changed
from the version of H1N1 that emerged in 2009 and has been
circulating around the world ever since.
These rare VDPVs arise when a virus used in the live vaccine reverts
from its weakened form and regains its virulence — a danger when vaccination rates are low, as they are in both places, allowing the vaccine
strain to
circulate and accumulate genetic mutations.
Called a DNA vaccine, it contains genetic snippets
from a Zika virus
strain that
circulated recently in Brazil to elicit immune responses.
What is more, the DNA in Haiti's cholera shows it was a single, recent introduction of a
strain from south Asia, though we don't know if it is
circulating in Nepal.
The
strain likely resulted
from a reshuffling of several avian influenza viruses
circulating in domestic ducks and chickens, Guan's group reported in 2013.
The virus
strains» family trees suggested that flu always
circulates locally in east Asia before emerging
from this crucible for its global excursions.
The virus itself will continue to mutate
from year to year — a process referred to as antigenic drift — and over time it becomes less well matched to the vaccine
strain, meaning that the antibodies you generate
from getting the vaccine may be less effective in neutralizing the
circulating virus.
From the American Veterinary Medical Association: It was recently brought to our attention that there are rumors
circulating online about the existence of two new
strains of canine distemper virus.