Sentences with phrase «from cystic fibrosis patients»

In lab experiments using tissue samples cultured from cystic fibrosis patients, scientists at the UNC School of Medicine and the UNC Marsico Lung Institute have shown that a new CF drug counteracts the intended beneficial molecular effect of another CF drug.

Not exact matches

«We are now exploring ways to reformulate antibiotics together with relevant vitamins for delivery into cystic fibrosis patients and assess their efficacy, so that patients can benefit from these findings.»

The scientists performed the tests in a laboratory setting using 100 different bacterial strains isolated from the lungs of pediatric cystic fibrosis patients of Seattle Children's Hospital and 42 bacterial strains isolated from hospitalized adult patients at UPMC.

In the Netherlands, based on research reported in 2016 in Science Translational Medicine, Clevers and colleagues are already using personalized gut organoids, derived from rectal biopsies, to test whether cystic fibrosis patients will benefit from available drugs.

«Because airway spheres from a patient with cystic fibrosis do not swell in our assay but airway spheres from a healthy person do, we can see whether adding a certain drug or combination of drugs causes them to swell more.

A multi-drug resistant infection that can cause life - threatening illness in people with cystic fibrosis (CF) and can spread from patient to patient has spread globally and is becoming increasingly virulent, according to new research published today in the journal Science.

Senior co-author Dr Alastair Innes from Western General Hospital, Edinburgh, UK adds, «Publication of this trial is a landmark for cystic fibrosis patients and we are particularly grateful to the many patients across the UK who gave their time and effort to participate and make this collaborative venture a success.»

On topics ranging from the proper care of terminal cancer patients to how the best cystic fibrosis doctors push their patients» life spans far beyond the mean, they have certainly educated this colleague.

He benefits from a medication that targets the underlying cause of the disease for a small subset of cystic fibrosis patients.»

Ten Years of Improvement Innovation in Cystic Fibrosis Care includes reports on a range of improvement initiatives, ranging from the impact of patient education on improving adherence to critical daily treatments, and strategies for boosting nutritional status.

New research comparing cystic fibrosis patients in the United States and Canada showed that, although the patients» nutritional status and lung function improved in both countries over the period from 1990 to 2013, the rate of improvement was faster in the United States.

And the technique will benefit not just cancer research but research into every disease driven by gene mutations, from cystic fibrosis to Alzheimer's disease — ultimately enabling customized treatments for patients in a way never before possible.

The study was funded by the U.S. Cystic Fibrosis Foundation using data from 45,456 patients in the U.S. Cystic Fibrosis Foundation Registry and 5,941 patients in the Canadian Cystic Fibrosis Registry from 1990 to 2013.

Twelve patients from the Northern Ireland Adult and Paediatric Cystic Fibrosis Centres participated in the study.

The study, funded by the U.S. Cystic Fibrosis Foundation, used data from 37,772 patients in the U.S. Cystic Fibrosis Foundation Registry and 5,149 patients in the Canadian Cystic Fibrosis Registry.

For example, organoids grown from the guts of individual cystic fibrosis patients are used to predict their response to drugs.

Pseudomonas aeruginosa can cause serious inflammations of the skin and the lung in patients with a weakened immune system, particularly in those suffering from the genetic disorder cystic fibrosis.

The course will use cultures from the Living Biobank at The HUB, which include organoids from patients with cystic fibrosis and various forms of cancer.

Meanwhile, Hans Clevers and colleagues applied CRISPR to disease correction in adult stem cells isolated from two patients with cystic fibrosis.

As proof - of - concept, the CFTR locus was repaired in single gut stem cells from two Cystic Fibrosis patients, using CRISPR / Cas9 technology in conjunction with homologous recombination.

Though every CF patient carries mutations in both copies of the same gene — coding for a protein called cystic fibrosis transmembrane conductance regulator or CFTR — symptoms can vary widely from patient to patient.

This has been used for many years to break up mucus in the lungs in patients suffering from cystic fibrosis, asthma and bronchitis, and is often used by HIV patients to boost their immune system.

The planTrue ™ carrier screening from True Health employs industry - leading next - generation sequencing technology to detect whether a patient is a carrier for conditions such as cystic fibrosis, spinal muscular atrophy, fragile X, and many others.

Less than 2 % of diseases, such as cystic fibrosis, Huntington's chorea, and beta thalassemia, result from a single faulty gene, and only about 5 % of cancer patients can attribute their diseases to heredity.