The potential of iPS cells to help treat everything
from damaged heart tissue to Parkinson's disease, has prompted intensive research that has looked into the use of skin fibroblast cells as an alternative to controversial embryonic stem cells.
Not exact matches
Nitric Oxide protects the
heart from damage caused by ischemia, or blocked blood flow to
heart tissue.
In the United States, about 720,000 residents experience a
heart attack annually, which means that hundreds of thousands of
heart patients are living with the disabling complications of
heart disease who could benefit
from therapies to repair and regenerate
damaged heart tissue.
Any
tissue (not just skin) that is chronically inflamed because of the persistent presence of pathogens, toxins or genetic
damage helps to spur illness,
from heart disease to cancer.
A previous study
from the MGH team found that injecting B cells into cardiac
tissue damaged by a
heart attack improved structural and functional recovery in an animal model.
Researchers
from the UNC School of Medicine have discovered that cells called fibroblasts, which normally give rise to scar
tissue after a
heart attack, can be turned into endothelial cells, which generate blood vessels to supply oxygen and nutrients to the injured regions of the
heart, thus greatly reducing the
damage done following
heart attack.
The result — the second such finding in the past year — suggests that similar cells
from human testicles might have similar powers, paving the way to creating replacement
tissue for men who have suffered
damage from heart attacks or other injuries and avoiding some of the controversy surrounding embryonic stem cells (ESC).
Stem cells so far have been used to mend
tissues ranging
from damaged hearts to collapsed tracheas.
Scientists
from the LoGrasso lab have been able to show in animal models that inhibiting a specific enzyme protects
heart cells and surrounding
tissue against serious
damage from heart attacks.
Friedreich's ataxiais an inherited disease that causes progressive
damage to the nervous system, resulting in symptoms ranging
from gait disturbance to speech problems; it can also lead to
heart disease and diabetes.The ataxia of Friedreich's ataxia results
from the degeneration of nerve
tissue in the spinal cord, in particular sensory neurons essential (through connections with the cerebellum) for directing muscle movement of the arms and legs.
These penetrate
tissue and heat up when excited by radio - frequency waves; and they have been shown to thaw arteries and
heart valve
tissue from pigs, as well as human skin cells, rapidly and evenly, without the typical
damage.
«The
damage from a
heart attack is typically permanent because
heart - muscle cells — deprived of oxygen during the attack — die and scar
tissue forms,» said Dr. Srivastava, who directs cardiovascular and stem cell research at Gladstone, an independent and nonprofit biomedical - research institution.
CINCINNATI - Scientists used an experimental targeted molecular therapy to block a matrix - forming protein in
heart cells
damaged by
heart attack, reducing levels of scarred muscle
tissue and saving mouse models
from heart failure.
«Our hope is to one day treat diseases like
heart failure or Parkinson's disease with drugs that help the
heart and brain regenerate
damaged areas
from their own existing
tissue cells.»
Adults over 65 are at increased risk for complications
from pneumonia, and serious cases that require hospitalization have been linked to long - term health issues like cardiovascular
tissue damage and an increased risk of
heart disease.
Ripe bananas contain a slightly higher concentration of antioxidant compounds than unripe bananas, says David L. Katz, M.D. Antioxidants are able to inhibit free radicals
from damaging DNA and cellular
tissue, and a diet rich in a variety of antioxidants may be instrumental in preventing cancer,
heart disease, diabetes and neurodegenerative disorders like Alzheimer's disease.
Compounds called polyphenols may protect your body
from the type of cell and
tissue damage that's linked to
heart disease and certain cancers.
And that's not all: Moringa leaves also have antioxidant activity that may protect the liver, kidneys,
heart, and lungs
tissues from damage, according to a 2015 review in Phytotherapy Research.
However, chronic and uncontrolled inflammation can cause
damage to cells,
tissue and organs and result in a range of diseases
from autoimmune diseases like Celiac Disease and rheumatoid arthritis, to obesity and
heart disease.
The study team examined
heart tissue removed
from patients undergoing ventricular implants and found that G6P can cause significant
damage to the
heart muscle.
However, when the
tissue is too
damaged, a replacement valve may be used
from another human
heart, an animal or a manufactured mechanical valve.»
Additionally, periodontal disease may lead to holes
from the mouth to the nasal passages,
damage to the
tissues around the teeth,
heart problems, and kidney failure.
If the heartbeat remains high for a long period of time, your dog could suffer
from heart tissue damage and
heart failure due to liquid build - up in the lungs.
Untreated, heartworms
damage the
tissues and blood vessels of the lungs and eventually lead to death
from congestive
heart failure.
ACT - activated clotting time (bleeding disorders) ACTH - adrenocorticotropic hormone (adrenal gland function) Ag - antigen test for proteins specific to a disease causing organism or virus Alb - albumin (liver, kidney and intestinal disorders) Alk - Phos, ALP alkaline phosphatase (liver and adrenal disorders) Allergy Testing intradermal or blood antibody test for allergen hypersensitivity ALT - alanine aminotransferase (liver disorder) Amyl - amylase enzyme — non specific (pancreatitis) ANA - antinuclear antibody (systemic lupus erythematosus) Anaplasmosis Anaplasma spp. (tick - borne rickettsial disease) APTT - activated partial thromboplastin time (blood clotting ability) AST - aspartate aminotransferase (muscle and liver disorders) Band band cell — type of white blood cell Baso basophil — type of white blood cell Bile Acids digestive acids produced in the liver and stored in the gall bladder (liver function) Bili bilirubin (bile pigment responsible for jaundice
from liver disease or RBC destruction) BP - blood pressure measurement BUN - blood urea nitrogen (kidney and liver function) Bx biopsy C & S aerobic / anaerobic bacterial culture and antibiotic sensitivity test (infection, drug selection) Ca +2 calcium ion — unbound calcium (parathyroid gland function) CBC - complete blood count (all circulating cells) Chol cholesterol (liver, thyroid disorders) CK, CPK creatine [phospho] kinase (muscle disease,
heart disease) Cl - chloride ion — unbound chloride (hydration, blood pH) CO2 - carbon dioxide (blood pH) Contrast Radiograph x-ray image using injected radiopaque contrast media Cortisol hormone produced by the adrenal glands (adrenal gland function) Coomb's anti- red blood cell antibody test (immune - mediated hemolytic anemia) Crea creatinine (kidney function) CRT - capillary refill time (blood pressure,
tissue perfusion) DTM - dermatophyte test medium (ringworm — dermatophytosis) EEG - electroencephalogram (brain function, epilepsy) Ehrlichia Ehrlichia spp. (tick - borne rickettsial disease) EKG, ECG - electrok [c] ardiogram (electrical
heart activity,
heart arryhthmia) Eos eosinophil — type of white blood cell Fecal, flotation, direct intestinal parasite exam FeLV Feline Leukemia Virus test FIA Feline Infectious Anemia: aka Feline Hemotrophic Mycoplasma, Haemobartonella felis test FIV Feline Immunodeficiency Virus test Fluorescein Stain fluorescein stain uptake of cornea (corneal ulceration) fT4, fT4ed, freeT4ed thyroxine hormone unbound by protein measured by equilibrium dialysis (thyroid function) GGT gamma - glutamyltranferase (liver disorders) Glob globulin (liver, immune system) Glu blood or urine glucose (diabetes mellitus) Gran granulocytes — subgroup of white blood cells Hb, Hgb hemoglobin — iron rich protein bound to red blood cells that carries oxygen (anemia, red cell mass) HCO3 - bicarbonate ion (blood pH) HCT, PCV, MHCT hematocrit, packed - cell volume, microhematocrit (hemoconcentration, dehydration, anemia) K + potassium ion — unbound potassium (kidney disorders, adrenal gland disorders) Lipa lipase enzyme — non specific (pancreatitis) LYME Borrelia spp. (tick - borne rickettsial disease) Lymph lymphocyte — type of white blood cell MCHC mean corpuscular hemoglobin concentration (anemia, iron deficiency) MCV mean corpuscular volume — average red cell size (anemia, iron deficiency) Mg +2 magnesium ion — unbound magnesium (diabetes, parathyroid function, malnutrition) MHCT, HCT, PCV microhematocrit, hematocrit, packed - cell volume (hemoconcentration, dehydration, anemia) MIC minimum inhibitory concentration — part of the C&S that determines antimicrobial selection Mono monocyte — type of white blood cell MRI magnetic resonance imaging (advanced
tissue imaging) Na + sodium ion — unbound sodium (dehydration, adrenal gland disease) nRBC nucleated red blood cell — immature red blood cell (bone marrow
damage, lead toxicity) PCV, HCT, MHCT packed - cell volume, hematocrit, microhematocrit (hemoconcentration, dehydration, anemia) PE physical examination pH urine pH (urinary tract infection, urolithiasis) Phos phosphorus (kidney disorders, ketoacidosis, parathyroid function) PLI pancreatic lipase immunoreactivity (pancreatitis) PLT platelet — cells involved in clotting (bleeding disorders) PT prothrombin time (bleeding disorders) PTH parathyroid hormone, parathormone (parathyroid function) Radiograph x-ray image RBC red blood cell count (anemia) REL Rocky Mountain Spotted Fever / Ehrlichia / Lyme combination test Retic reticulocyte — immature red blood cell (regenerative vs. non-regenerative anemia) RMSF Rocky Mountain Spotted Fever SAP serum alkaline phosphatase (liver disorders) Schirmer Tear Test tear production test (keratoconjunctivitis sicca — dry eye,) Seg segmented neutrophil — type of white blood cell USG Urine specific gravity (urine concentration, kidney function) spec cPL specific canine pancreatic lipase (pancreatitis)-- replaces the PLI test spec fPL specific feline pancreatic lipase (pancreatitis)-- replaces the PLI test T4 thyroxine hormone — total (thyroid gland function) TLI trypsin - like immunoreactivity (exocrine pancreatic insufficiency) TP total protein (hydration, liver disorders) TPR temperature / pulse / respirations (physical exam vital signs) Trig triglycerides (fat metabolism, liver disorders) TSH thyroid stimulating hormone (thyroid gland function) UA urinalysis (kidney function, urinary tract infection, diabetes) Urine Cortisol - Crea Ratio urine cortisol - creatine ratio (screening test for adrenal gland disease) Urine Protein - Crea Ratio urine protein - creatinine ratio (kidney disorders) VWF VonWillebrands factor (bleeding disorder) WBC white blood cell count (infection, inflammation, bone marrow suppression)