Sentences with phrase «from death of cells»

It results from the death of cells critical for vision: retinal pigment epithelial cells (RPE) and photoreceptor cells.

AMD, a major cause of irreversible vision loss in the elderly, results from death of cells critical for vision: RPE and photoreceptor cells.

Not exact matches

Typically, the group consists of a «tie - down team» who escort the prisoner from his cell to the death chamber and then strap him to the gurney; medically trained personnel who set the intravenous lines; and those, like Bracey and Baxley, who sit on the other side of a glass wall and press the buttons to inject the lethal drugs into the prisoner once the team leader gives the order.

From single - cell fertilized egg to baby to teenager to adult to old age to death is a single process of one individual, not a series of different individuals replacing each other.

Once triggered, the «subroutine» of cancer results in a neoplasm (a group of new, cancerous cells) becoming mobile; this is metastasis, responsible for most deaths from cancer.

This could offer a technique to help in the prognosis of metastases, the spreading of cancer cells to other regions of the body, responsible for 90 per cent of deaths from cancer.

With no outlet ahead offering a way of escape from total death, no supreme center of personalization to radiate love among the human cells, it is a frozen world that in the end must disintegrate entirely in a Universe without heart or ultimate purpose.

To develop this sense of «belonging» will be a way in which, here and now, life can become meaningful; for in the little cells of Christian faith and love which are our parishes as they ought to be, hope is implanted m men's hearts that lifts them above, and yet sends them back into, the community life of which they are also a part, knowing that they have passed from death into life, because they love the brethren and are therefore empowered to bring a stream of fresh, courageous, loving life to a sadly disillusioned and despairing world.

Jaundice which is due to the rapid, abnormal destruction of the baby s blood cells often resulted, in the past, in serious injury or even death for the baby, but this is different from what most babies are now experiencing.

New York City has agreed to pay $ 5.75 million to settle a lawsuit stemming from the 2013 death of a mentally ill inmate, Bradley Ballard, who was found naked and covered in urine and feces after being locked in a cell at Rikers Island for six days.

The study, published Feb. 5 in Nature Neuroscience, showed that the patients» nerve cells — converted directly from patients» skin cells — exhibited «symptoms» of the disorder, including DNA damage, dysfunctional mitochondria and cell death.

Published in the Journal of Experimental Medicine online Oct. 31, the new study found that infliximab prevents TNF alpha from speeding the death of Paneth cells, which protect the gut from microbes.

Animal cells take up carbon - 14 when they are formed, and because the decay rate of carbon - 14 is known, the time of death can be deduced from the amount of isotope left.

Both diseases result from the death of retinal cells, a process that Lanza suspects can be slowed or even halted using stem - cell - derived replacements.

A strong supporter of human embryo stem cell research, the senator joined with hundreds of legislators from both parties after Ronald Reagan's death in a renewed plea for Bush to remove restrictions.

The results could provide insights into the Zika virus» recent emergence as a global health emergency, and also point to inhibitors of the protein p53 as potential leads for drugs that could protect brain cells from cell death.

Lo's team set out to find ways to further weaken the tumors, since the drug addiction response (which can range from a mere slow down of the cancer's growth rate to cancer cell death), can be used to improve clinical outcomes.

Nicotine from cigarettes is a highly addictive drug that can stimulate cell growth and block cell death — two hallmark characteristics of cancer.

In a study published in 2006, he and other Johns Hopkins researchers tested two compounds similar to CGP3466B to see if they would block GAPDH from triggering cell death under the types of highly stressful conditions that would normally cause apoptosis.

A molecule that helps cancer cells evade programmed self - destruction, an internal source of death, might also help malignant cells hide from the immune system, an external source of death.

Giving the mice antibiotics helped gemcitabine kill tumor cells, increasing the number of tumor cells going through a type of cell death called apoptosis from about 15 percent to 60 percent or more.

«We also know that this RhoB pathway, once turned on, can stimulate the expression of two proteins: p21, which prevents cells from replicating, and BIM, which induces cell death — both of which can help stop cancer growth.»

They discovered that while overall rates of infection remained the same, there was significantly more CD4 T cell death if HIV was spread by infection from other cells than by free - floating virus.

Eventually, she says, it might be possible to use our increased understanding of RFX transcription factor to treat hearing loss, by either protecting hair cells from death or fostering their growth.

mTOR controls expression of proteins that alter mitochondrial structure and function in ways that unexpectedly protect cells from death, the team reported.

The primary cause of death from breast cancer is the spread of tumor cells from the breast to other organs in the body.

The normal function of the UPR pathway is to protect cells from stress but it can also trigger their death if the stress is not resolved.

The researchers from UC Berkeley, UC San Francisco Benioff Children's Hospital Oakland Research Institute (CHORI) and the University of Utah School of Medicine hope to re-infuse patients with the edited stem cells and alleviate symptoms of the disease, which primarily afflicts those of African descent and leads to anemia, painful blood blockages and early death.

Now, 60 years after Turing's death, researchers from Brandeis University and the University of Pittsburgh have provided the first experimental evidence that validates Turing's theory in cell - like structures.

They also tested other chemicals known to prevent the other two forms of cellular suicide, but only CGP3466B protected mouse nerve cells in the brain from death by cocaine.

«The key thing is that we've moved away from a disease - specific mechanism to a more generic cause of cell death,» she says.

Researchers from Ludwig - Maximilians - Universitaet (LMU) in Munich have demonstrated how deregulation of an epigenetic mechanism that is active only in the early phases of neurogenesis triggers the subsequent death of neural cells.

Arising from the Schwann cells of the vestibular (balance) nerve, these tumors can grow to the point of damaging nearby structures — and can lead to death by compressing the brainstem.

Both discoveries came from studies of mitochondria, the powerhouses of the cell that burn nutrients for energy but also play a key role in signaling, cell death and growth.

A study published March 7th by Cell Press in the journal Cell reveals that a compound derived from fats found in fish oils prevents death in influenza - virus - infected mice, even at advanced stages of disease.

Finnish scientists from the University of Helsinki, investigating how Myc re-engineers metabolic pathways in cells, have identified an unexpected branch in the pathway - a branch that ends to cell death (apoptosis).

Looking for the presence of chemicals commonly seen during inflammation and cell death, the researchers noticed abnormally high levels of RIPK1 — a known promoter of cell death — in spinal cord cells from mice lacking OPTN.

But the pH - responsiveness also allows the bacterium to escape a certain death by detaching from epithelial - and mucus cells that are shed into the gastric juice,» says Jeanna Bugaytsova, researcher at Department of Medical Biochemistry and Biophysics and first - author of the article.

The fatty acid also increased the effectiveness of Herceptin, a drug made from antibodies that latch onto HER2 proteins and trigger the death of cancer cells.

Previous studies from these researchers have showed that FL118 induces cancer cell death, or apoptosis, by inhibiting expression of multiple cell - survival proteins (survivin, Mcl - 1, XIAP or cIAP2).

A section of a tumor organoid grown from cells derived from a patient with high - grade serous ovarian cancer (left) and a mini-tumor treated with ReACp53, resulting in extensive cancer cell death.

Adds Liu: «With metastatic cancers accounting for around 90 % of deaths from solid tumors, the hope is that one day a device that can enable the analysis of single tumor cells circulating in the blood could make a big difference in early diagnosis, detection and monitoring of numerous types of cancer, without invasive biopsies.»

Inflammation also erodes telomeres, the «caps» at the ends of chromosomes that protect genes from degradation, which can lead to early cell death, premature aging and even cancer.

In contrast to necrosis, which is a form of cell death that results from acute tissue injury and provokes an inflammatory response, PCD is carried out in a regulated process that generally confers advantages during an organism's life cycle.

Genomic data from the HeLa cell line are also being released with the final version of the paper as a result of discussions between leaders of the National Institutes of Health (NIH) and relatives of Henrietta Lacks, from whose cervical tumor the original HeLa cell line was derived prior to her death in 1951.

For pancreatic cancer, the team saw signs of pancreatic cell death in the blood of about half of 42 patients; the group even distinguished cancer from pancreatitis — which also raised cell - free DNA levels in seven of 10 patients — by incorporating a test for a cancer mutation.

While doctors, nutritionists and researchers have known for a long time that saturated fats contribute to some of the leading causes of death in the United States, they haven't been able to determine how or why excess saturated fats, such as those released from lard, are toxic to cells and cause a wide variety of lipid - related diseases, while unsaturated fats, such as those from fish and olive oil, can be protective.

Cells that detach from their environment undergo a form of programmed cell death called anoikis.

Next, Grima looked at cell death in cultured neurons with a healthy or a mutant form of Huntingtin, or with a mutant form of Huntingtin that was treated with small amounts of an experimental drug called KPT - 350, one that prevents a nuclear export protein, Exportin - 1, from shuttling proteins and RNA out of the nucleus.

Under normal circumstances, cells must have some way of preventing the death domains of neighbouring receptors from coming together.