However, other major effects of FeLV infection are severe immunosuppression and development of anaemia, and more cats will die of these complications than
from development of tumours.
Not exact matches
Peng Loh
of the National Institute
of Child Health and Human
Development in Bethesda, Maryland, and colleagues studied
tumours from 99 people with liver cancer.
Published in the journal Cancer Research, the discovery has potential to lead to the
development of a blood test that could predict whether cancer will spread
from the prostate
tumour to other parts
of the body.
Their experiments in pre-clinical models proved to be successful, confirming lower
tumour development with the regulation
of the proteins that affect production
of VLDL (precursors
of LDL) and uptake
of LDL by receptors
from the liver.
Breast cancer cells that spread to other parts
of the body break off and leave the primary
tumour at late stages
of disease
development, scientists
from the Wellcome Trust Sanger Institute and their collaborators have found.
By conducting an RNA - sequencing experiment
of 103 matched
tumour and normal colon mucosa samples
from Danish CRC patients, 90
of which were germline - genotyped, researchers
from the collaborative European project SYSCOL show that both inherited and acquired mutations in non-coding regions
of the genome also contribute to cancer
development and progression (Linda Koch, Nature Reviews Genetics).
Understanding the processes that restrain mutant cells
from developing into
tumours, and how they are breached when cancers do form will guide the
development of strategies to reduce the chance
of cancer
development in individuals who have acquired a high level
of mutations.