Sentences with phrase «from different organs»

First, we identified Tie2 expression in cultured pericytes isolated from different organs and established cellular and signalling readouts of Ang - Tie signalling in cultured pericytes.

Efforts to study the molecular mechanisms that mediate these complex processes in different anatomical compartments have been impeded by difficulties in the isolation and propagation of endothelial cells from different organs.

This is also exemplified by the fact that CSCs from different organs have been isolated by using different markers (1, 19).

The constitutive expression of these endothelial cell adhesion molecules was very similar for most of the lines derived from different organs, i.e., very low expression levels of E-selectin and VCAM - 1 and more pronounced expression of ICAM - 1.

We capitalized on one of the innate responses of microvascular endothelial cells, i.e., the up - regulation of cell adhesion molecules in response to inflammatory agents, to generate endothelial cell lines from different organs.

To overcome these limitations, we used two - color flow cytometry to identify and select microvascular endothelial cells from primary cultures obtained from different organs of mice whose tissues harbor a temperature - sensitive SV40 large T antigen (H - 2Kb - tsA58 mice; ImmortoMice).

They showed that the iKnife could distinguish normal and tumor tissues from different organs, such as breast, liver, and brain, and could even identify the origin of a tumor that was a metastasis, a secondary growth seeded by a primary tumor elsewhere in the body.

But dolphins, fish, and platypuses each evolved the receptor cells independently, from different organs unique to each lineage.

«On the other hand, there was this idea that the lizard third eye developed from a different organ, called the parapineal, which is well developed in lampreys.

Sometimes it arises from the kidneys (primary), much more often the cancer has spread to the kidneys from a different organ (secondary or metastatic).

Not exact matches

«In the long term, we want to be able to send energy to and communicate with implants all over the body, to record data from a variety of organs in many different ways, maybe even report on the conditions of tumors or cancer therapies,» Maharbiz says.

Now, to be clear, donating your body to science is different from being an organ donor on your license.

But even if Thomas's physiology is (from our perspective) wobbly, we can acknowledge that he is again on to something: understanding (for instance) colours is different from sensing colours.There is a sort of distance which would not be there if the operation of the intellect were tied essentially to a physical organ.

The function proper to the first organ is that of receiving [percevoir] each particular impression, of attaching signs to it, of combining the different impressions, of comparing them with each other, of drawing from them judgments and resolves; just as the function of the other organ is to act upon the nutritive substances whose presence excites it, to dissolve them, and to assimilate their juices to our nature.

truthfolower01 — for a wolf to evolve into a chihuahua and a great dane (and every breed in between) you must accept that the spinal chord can evolve from its original length to lengths from a few inches to a few feet, for fundamental organs like the heart, lungs and stomach to evolve into vastly different sizes, for limb length to evolve into greatly different sizes, for facial structure to evolve into shapes as different as the dachshund and the pug, for se.xual organs to evolve into very different sizes, for hair length, color and curliness to evolve, for sense organs like smell and bark to evolve.

Babies bodies are different from adults: they're not fully developed, so they can suffer severe injuries to their neck, spine and internal organs from the force of a crash, especially if they are not strapped in properly or in the wrong type of car seat.

In this sense, donating breast milk isn't so different from organ donation.

Although blood cells serve multiple roles in the body and have complex interactions with other cellular materials, most synthetic blood products have aimed to just stick to the bare basics — shuttling oxygen from the lungs to different vital organs and then bringing carbon dioxide back to the lungs to be exhaled.

Published in the Proceedings of the National Academy of Sciences, the study found that many species from the two plateaus underwent different mutations to produce the same result: hemoglobins more adept at snaring oxygen from the lungs before sharing it with the other organs that depend on it.

Collaboratively, the research team sequenced the DNA that encodes the genes as well as the RNA from the insect at different developmental stages, to identify when different genes are expressed and in which tissues and organs.

The researchers collected samples from different mouse organs, and identified the molecules with heavier carbon when separating out the metabolites by weight.

Although they found genetic drivers in the metastases that originated in the primary tumors, the researchers also found genetic variation between metastases in different organs coming from the same patient.

Fat in the body, including around the organs, is known to come in different colours, from brown to white.

This suggests that the brain learns foreign words more easily when they are associated with information from different sensory organs.

Recent advances in single - cell genomics technology has made it possible to separate individual cells from different tissues and organs, and measure the sets of RNA messages — called the transcriptome — which help give each cell its own identity.

Researchers have grown them from many different organs; they have also created organoids from tumor cells to mimic cancers.

A compound called 10β,17β - dihydroxyestra 1,4 dien -3-one (DHED), they found, relies on an enzyme in the brain to be converted from its «prodrug» form into the active form of estrogen; other organs in the body use different starting blocks to generate the hormone.

In an effort to encourage more people to register as organ and tissue donors, folks at Penn Medicine are tackling the issue from a few different angles — from advocacy to research to policy.

«Although sex - role reversal has been identified in several different animals, Neotrogla is the only example in which the intromittent organ is also reversed,» says Kazunori Yoshizawa from Hokkaido University in Japan.

From these three cell populations different functional tissue cells arise, such as skin cells, muscle cells, and specific organ cells.

Scientists from the Leibniz Institute for Zoo and Wildlife Research (IZW) investigated the composition of bacterial communities in different digestion - associated organs but found no unusual or special microbial communities when they compared these with those of other mammals.

This is interesting, given that muscle / lean muscle mass ratios of non-skeletal muscle organs from IL - 15Rα — KO mice, such as the heart, spleen, and kidneys, were not significantly different from those of B6129 controls.

The selection strategy targeted cell populations expressing the inducible endothelial cell adhesion molecules, E-selectin and VCAM - 1, and proved successful in generating microvascular endothelial cell lines from a number of different organs.

The study also shows that viral infection also causes major adaptations in the tumour cell, and that virus - positive tumours from widely different organs can therefore display considerable similarities.

Mature miR - 7 is individually transcribed and processed from 3 different gene locus in human genome, and it is highly expressed in parts of the brain, eye, and pancreas, suggesting its role in the development of these organs (20 — 22).

However, when these organ weights were normalized to lean muscle mass, the organ / lean muscle mass ratios were not significantly different from B6129 control mice (Figure 4, F — H).

These can lead to new traits, such as altered coloration, new susceptibility to disease or protection from it, or different shaped features (such as legs, antennae, toes or internal organs).

However, efforts to examine the in vitro behavior of tumor cells with endothelial cells from different anatomical regions have been prohibited because, in large part, of the limited number of organ - derived endothelial cell lines available for study.

The immortalized endothelial cell lines established from H - 2Kb - tsA58 mice provide, for the first time, a cell culture system to examine factors regulating angiogenesis and tumor cell arrest in different organ systems.

«In this study, we have a narrow focus on diabetes only,» wrote Tolstrup, «but since alcohol is related to more than 50 different diseases and conditions — reflecting that alcohol affects virtually every organ system of the body — any recommendations about how to drink and how much to drink should not be inferred from this study or any study investigating associations between alcohol and a single outcome.»

We can obtain iPS cells from an individual's skin or blood and program them into different tissue types to create patient - specific Organ - Chips.

Beverly Emerson studies how different genes are turned on and off through the course of a cancer — from the time cells become precancerous until the time they develop into a mature cancer and spread to new organs.

They used a method to identify genes that are co-expressed with already known endothelial - enriched genes and analysed RNA sequencing data from 124 unprocessed tissue samples from 32 different organs.

«It turned out cancers are very different from one organ to another and from person to person.

This symposium will bring together researchers from different fields to enhance our understanding of how organoids can be formed and maintained, how they can be used to study disease and how we might eventually use them to regenerate and replace human organ tissue.

«This was very different from all the other organ systems where when you look at the tissue there's something to see that is the physical equivalent or correlate of the disease,» Lichtman tells us.

According to the grant's description, «the communication required to establish the symbiosis between two widely different species occurs between cell layers in tissues, between organs in the plant, and across a time span from hours to days.»

Our strong expertise allows us study lipid - protein interaction based phenomena at different scales, from the organ and cellular systems down to minimal synthetic systems in which we can control the proteins as well as the lipid, for instance to monitor the allosteric effects of specific lipids on fundamental receptors such as the EGF receptor (Coskun et al (2011) PNAS) and the insulin receptor.

March 13, 2017 Parallel cellular pathways activate the process that controls organ growth A new study from the University of Chicago suggests that while proteins that control organ growth accumulate around the edges of cells, they actually function at a different cellular site.

A drug that prevents myosin from working in cancer cells could keep them from invading other cells or metastasize into different organs.