Sentences with phrase «from endoplasmic»

Furthermore, translocation of several cholesterogenic enzymes from the endoplasmic reticulum to other cell compartments can occur under various conditions, thereby regulating levels and sites of intracellular cholesterol accumulation.

α2B - adrenergic receptor interaction with tubulin controls its transport from the endoplasmic reticulum to the cell surface.

Distinct Pathways for the Trafficking of Angiotensin II and Adrenergic Receptors from the Endoplasmic Reticulum to the Cell Surface.

Multiple molecular determinants in the carboxyl terminus regulate dopamine transporter export from endoplasmic reticulum.

Anterograde trafficking of G protein - coupled receptors: function of the C - terminal F (X) 6LL motif in export from the endoplasmic reticulum.

Di - acidic Motifs in the Membrane - distal C Termini Modulate the Transport of Angiotensin II Receptors from the Endoplasmic Reticulum to the Cell Surface.

A conserved motif for the transport of G protein - coupled receptors from the endoplasmic reticulum to the cell surface.

Transit of a CD8 - p24 chimera from the endoplasmic reticulum through the Golgi complex was slowed when the phenylalanine motif was mutated, suggesting that this motif may function as an anterograde transport signal.

Autophagosomes arise from the endoplasmic reticulum (ER)-- a network of tubular membranes — and actin dynamics is key in their formation and movement.

The researchers found that when the cells were stressed, they quickly moved mRNAs from the endoplasmic reticulum to the cytosol.

Hypertension drug that protects cell from endoplasmic reticulum stress and preserves oligodendrocytes and myelin during inflammation

Protein trafficking from the endoplasmic reticulum (ER) to the Golgi apparatus involves specific uptake into coat protein complex II (COPII)-- coated vesicles of secretory and of vesicle targeting (v - SNARE) proteins.

Not exact matches

An international group of researchers led by Professor Christoph Hess from the Department of Biomedicine at the University of Basel and University Hospital Basel have now found a structure that accounts for the rapid immunologic memory of particular immune cells (CD8 + memory T cells): these important memory cells form multiple connections between mitochondria — the powerhouses of cells — and the endoplasmic reticulum, the site of protein production.

Bottom: Human epithelial cells from breast tissue showing the effects of endoplasmic reticulum stress (blue) which fills the entire cell structure.

This information flow may also be followed through the cell as it travels from the DNA in the nucleus, to the Cytoplasm, to the Ribosomes and the Endoplasmic Reticulum, and finally to the Golgi Apparatus, which may package the final products for export outside the cell.

It turns out that neuropathic pain is triggered when the body experiences endoplasmic reticulum (ER) stress, a condition in which the production and transport of protein exceeds the cells» capacities, say researchers from the University of California, Davis.

In addition, gastrocnemius muscles from IL - 15Rα — KO mice expressed higher levels of mRNA for the sarcoplasmic endoplasmic reticulum calcium ATPase - II (SERCA2) and lower mRNA expression and protein content of the calcium - binding protein calsequestrin (Figure 5, F and G).

«This has been an area of discussion for many years, as to whether there is the possibility of this translocation of ApoE from the secretory pathway, from the ER [endoplasmic reticulum] and the Golgi, where clearly it is predominantly located,» he continued.

Abbreviations: Aβ, amyloid β - peptide; AD, Alzheimer's disease; ALS, amyotrophic lateral sclerosis; Ambra1, activating molecule in Beclin -1-regulated autophagy; AMPK, AMP - activated protein kinase; APP, amyloid precursor protein; AR, androgen receptor; Atg, autophagy - related; AV, autophagic vacuole; Bcl, B - cell lymphoma; BH3, Bcl - 2 homology 3; CaMKKβ, Ca2 + - dependent protein kinase kinase β; CHMP2B, charged multivesicular body protein 2B; CMA, chaperone - mediated autophagy; 2 ′ 5 ′ ddA, 2 ′, 5 ′ - dideoxyadenosine; deptor, DEP - domain containing mTOR - interacting protein; DRPLA, dentatorubral pallidoluysian atrophy; 4E - BP1, translation initiation factor 4E - binding protein - 1; Epac, exchange protein directly activated by cAMP; ER, endoplasmic reticulum; ERK1 / 2, extracellular - signal - regulated kinase 1/2; ESCRT, endosomal sorting complex required for transport; FAD, familial AD; FDA, U.S. Food and Drug Administration; FIP200, focal adhesion kinase family - interacting protein of 200 kDa; FoxO3, forkhead box O3; FTD, frontotemporal dementia; FTD3, FTD linked to chromosome 3; GAP, GTPase - activating protein; GR, guanidine retinoid; GSK3, glycogen synthase kinase 3; HD, Huntington's disease; hiPSC, human induced pluripotent stem cell; hVps, mammalian vacuolar protein sorting homologue; IKK, inhibitor of nuclear factor κB kinase; IMPase, inositol monophosphatase; IP3R, Ins (1,4,5) P3 receptor; I1R, imidazoline - 1 receptor; JNK1, c - Jun N - terminal kinase 1; LC3, light chain 3; LD, Lafora disease; L - NAME, NG - nitro - L - arginine methyl ester; LRRK2, leucine - rich repeat kinase 2; MIPS, myo - inositol -1-phosphate synthase; mLST8, mammalian lethal with SEC13 protein 8; MND, motor neuron disease; mTOR, mammalian target of rapamycin; mTORC, mTOR complex; MVB, multivesicular body; NAC, N - acetylcysteine; NBR1, neighbour of BRCA1 gene 1; NOS, nitric oxide synthase; p70S6K, ribosomal protein S6 kinase - 1; PD, Parkinson's disease; PDK1, phosphoinositide - dependent kinase 1; PE, phosphatidylethanolamine; PI3K, phosphoinositide 3 - kinase; PI3KC1a, class Ia PI3K; PI3KC3, class III PI3K; PI3KK, PI3K - related protein kinase; PINK1, PTEN - induced kinase 1; PKA, protein kinase A; PLC, phospholipase C; polyQ, polyglutamine; PS, presenilin; PTEN, phosphatase and tensin homologue deleted from chromosome 10; Rag, Ras - related GTP - binding protein; raptor, regulatory - associated protein of mTOR; Rheb, Ras homologue enriched in brain; rictor, rapamycin - insensitive companion of mTOR; SBMA, spinobulbar muscular atrophy; SCA, spinocerebellar ataxia; SLC, solute carrier; SMER, small - molecule enhancer of rapamycin; SMIR, small - molecule inhibitor of rapamycin; SNARE, N - ethylmaleimide - sensitive factor - attachment protein receptor; SOD1, copper / zinc superoxide dismutase 1; TFEB, transcription factor EB; TOR, target of rapamycin; TSC, tuberous sclerosis complex; ULK1, UNC -51-like kinase 1; UVRAG, UV irradiation resistance - associated gene; VAMP, vesicle - associated membrane protein; v - ATPase, vacuolar H + - ATPase; Vps, vacuolar protein sorting

Within the cell, these calcium ions bind to activator proteins, which help release a flood of calcium ions from storage vesicles of the endoplasmic reticulum (ER) inside the cell.