To extend novel observations generated
from epidemiology studies to translational studies with direct clinical relevance.
Not exact matches
In case you missed it, a recent landmark
study published in the peer reviewed International Journal of
Epidemiology found that risk for coronary heart disease, stroke, total cardiovascular disease and death other than
from cancer was reduced with each 200g a day increase in fruit and vegetables up to 800g a day, and 600g a day for cancer.
So far at least, the data, says Dawn Comstock, PhD, an associate professor of
Epidemiology for the Pediatric Injury Prevention, Education, and Research (PIPER) program at the Colorado School of Public Health, MomsTeam Institute Board of Advisor and a co-author of a 2014
study on injuries in high school lacrosse [5], «is quite clear - boys most commonly sustain concussions (nearly 75 %)
from athlete - athlete contact, the kind of mechanism we all know helmets don't always do a great job preventing - while girls most commonly sustain concussions (nearly 64 %)
from being struck by the ball or the stick, the kind of mechanism that helmets are actually quite good at preventing.
From the * Department of Child and Adolescent Psychiatry / Psychology; † Generation R
Study Group, Erasmus University Medical Center, Rotterdam, The Netherlands; ‡ Centre for Child and Family
Studies, Leiden University, Leiden, The Netherlands; § Departments of Public Health; ‖ Pediatrics; ¶
Epidemiology, Erasmus University Medical Center, Rotterdam, The Netherlands.
There are lots of good
studies in the West on breastfeeding and immune function but I wanted to stay away
from Western psychology and
epidemiology papers in my post because of their over-reliance on the children of urban, white, and educated parents (an unrepresentative sample).
Professor Keith Godfrey,
from the Medical Research Council Lifecourse
Epidemiology Unit and the National Institute for Health Research Southampton Biomedical Research Centre, and a member of the
study team, said: «The new findings provide the first direct evidence linking faltering of a baby's growth in the womb with epigenetic modifications that themselves may increase the risk of childhood obesity.
Thomas Smith, who
studies the
epidemiology of malaria at the Swiss Tropical Institute in Basel, says it may be premature to say exactly what the efficacy is based on this early data
from the trial, which is still ongoing.
The population - based observational
study using patients
from the Surveillance,
Epidemiology and End Results (SEER) Medicare database focused on 41,275 men diagnosed with localized prostate cancer between 2004 and 2007 and observed through 2009.
Dr David Carslake, the
study's lead author and Senior Research Associate
from the MRC Integrative
Epidemiology Unit (IEU) at the University of Bristol, said: «An alarming increase in obesity levels across the world which have risen
from 105 million in 1975 to 641 million in 2014, according to a recent Lancet
study, create concern about the implications for public health.
In order to assess whether an improved diet could reduce the risk of ovarian cancer in African - American women, Qin analyzed the diets of 415 women with ovarian cancer and 629 control patients, using data
from the African - American Cancer
Epidemiology Study, a population - based case - control study of ovarian cancer in African - American women in 11 sites in the United St
Study, a population - based case - control
study of ovarian cancer in African - American women in 11 sites in the United St
study of ovarian cancer in African - American women in 11 sites in the United States.
«Pancreatic cancer is really unique and different
from other cancers,» said
study co-author Ka He, chair of the Department of
Epidemiology and Biostatistics at the IU School of Public Health - Bloomington.
The UTMB
study analyzed 64,507 cervical cancer cases collected
from 1973 - 2009 by the National Cancer Institute Surveillance,
Epidemiology and End Results program.
The
study examined 328 patients with cervical cancer and 1,312 controls, matched on age and decade, who enrolled in a hospital - based case - control
study drawn
from 26,831 patients who received treatment at Roswell Park Cancer Institute and completed the Patient
Epidemiology Data System questionnaire between 1982 and 1998.
«These are extremely important findings for those who are suffering
from high blood pressure,» said Andrew Mente, lead author of the
study, a principal investigator of PHRI and an associate professor of clinical
epidemiology and biostatistics at McMaster's Michael G. DeGroote School of Medicine.
For those who aren't familiar with it, the «tipping point» is a concept
from epidemiology (popularized by the best - selling book by Malcolm Gladwell) that suggests that small changes accumulate innocuously until a critical mass is reached, at which point a large - scale, irreversible change occurs in the system under
study.
The lead researcher for the
study, Professor Gita Mishra, Professor of Life Course Epidemiology and Director of the Australian Longitudinal Study on Women's Health at the University of Queensland, Australia, said: «If the findings from our study were incorporated into clinical guidelines for advising childless women from around the age of 35 years who had their first period aged 11 or younger, clinicians could gain valuable time to prepare these women for the possibility of premature or early menop
study, Professor Gita Mishra, Professor of Life Course
Epidemiology and Director of the Australian Longitudinal
Study on Women's Health at the University of Queensland, Australia, said: «If the findings from our study were incorporated into clinical guidelines for advising childless women from around the age of 35 years who had their first period aged 11 or younger, clinicians could gain valuable time to prepare these women for the possibility of premature or early menop
Study on Women's Health at the University of Queensland, Australia, said: «If the findings
from our
study were incorporated into clinical guidelines for advising childless women from around the age of 35 years who had their first period aged 11 or younger, clinicians could gain valuable time to prepare these women for the possibility of premature or early menop
study were incorporated into clinical guidelines for advising childless women
from around the age of 35 years who had their first period aged 11 or younger, clinicians could gain valuable time to prepare these women for the possibility of premature or early menopause.
The researchers analyzed data collected between 2002 and 2011
from patients in the Rochester
Epidemiology Project, a National Institutes of Health - funded medical records pool that makes Olmsted County, Minn., the home of Mayo Clinic, one of the few places worldwide where scientists can
study virtually an entire geographic population to identify health trends.
Published online in the International Journal of
Epidemiology, a new
study of 80,342 participants, including 15,220 current smokers, from the Copenhagen General Population Study has shown that smokers who consume a high amount of tobacco are more likely to weigh
study of 80,342 participants, including 15,220 current smokers,
from the Copenhagen General Population
Study has shown that smokers who consume a high amount of tobacco are more likely to weigh
Study has shown that smokers who consume a high amount of tobacco are more likely to weigh less.
«It has been thought that the diarrhea that results
from Cryptosporidium infections was causing the dehydration and malnutrition that can lead to stunted growth,» says the
study's leader Poonum Korpe, MD, an assistant scientist in the Department of
Epidemiology at the Bloomberg School.
In this
study, Dr Deborah Hasin, Professor of
Epidemiology at Columbia University Medical Center, New York, USA and colleagues examined the relationship between the legalisation of medical marijuana and adolescent marijuana use by analysing national «Monitoring the Future» survey data *
from over one million students in the 8th, 10th, and 12th grades (aged 13 - 18) between 1991 and 2014 — a period when 21 contiguous states passed laws allowing marijuana use for medical purposes.
In a new
study published in the journal PLOS One, Jennifer Horney, PhD, associate professor and head of the Department of
Epidemiology and Biostatistics in the Texas A&M School of Public Health, along with researchers
from Texas A&M and the Pacific Northwest National Lab, examined concentrations of polycyclic aromatic hydrocarbons (PAHs) before and after Hurricane Harvey in the Houston environmental justice neighborhood of Manchester.
Dr Annie Herbert,
from UCL Institute of
Epidemiology and Healthcare, said: «A huge amount of deaths after adversity - related injury in our
study were
from suicide or drug or alcohol abuse, which to an extent should be preventable.
The
study by Drs. Cande Ananth, Katherine Keyes, and Ronald Wapner in the Departments of
Epidemiology and Obstetrics and Gynecology, examined data on 120 million births in the United States between 1980 and 2010
from national hospital discharge surveys.
The Mayo
study used the Rochester
Epidemiology Project medical records database to identify all neurologist - confirmed Parkinson's cases
from January 1976 through December 2013 among Olmsted County, Minn., residents.
Data
from this
study were obtained
from the Compressed Mortality File (CMF) administered by the Office of Analysis,
Epidemiology, and Health Promotion of the National Center for Health Statistics, Centers for Disease Control and Prevention (CDC), and the Internet - based CDC WONDER, a wide - ranging online data epidemiologic research system.
A research consortium bringing together teams
from Inserm, the Nancy and Poitiers University Hospitals, and the Centers for Disease Control and Prevention (CDC, Atlanta, USA), and coordinated by the Inserm and University of Grenoble Environmental
Epidemiology team (Unit 823), has just published an epidemiological
study indicating that exposure to certain phenols during pregnancy, especially parabens and triclosan, may disrupt growth of boys during fetal growth and the first years of life.
Adrian Grant, director of the Perinatal Trials Service at the National Perinatal
Epidemiology Unit in Oxford, one of the two coordinating centres for the trial, says such a
study will help to prevent medical and surgical methods
from being introduced without thorough testing.
Infections with the intestinal superbug C. difficile nearly doubled
from 2001 to 2010 in U.S. hospitals without noticeable improvement in patient mortality rates or hospital lengths of stay, according to a
study of 2.2 million C. difficile infection (CDI) cases published in the October issue of the American Journal of Infection Control, the official publication of the Association for Professionals in Infection Control and
Epidemiology (APIC).
Researchers
from the Detroit Medical Center (DMC), a seven - hospital system in southeastern Michigan, conducted a large
study to understand the
epidemiology of CDI readmissions, analyzing 51,353 all - cause discharges between January 1 and December 31, 2012.
Lead author of the
study, Dr Simone Ribero, a dermatologist
from the Department of Twin Research and Genetic
Epidemiology at King's, said: «For many years dermatologists have identified that the skin of acne sufferers appears to age more slowly than in those who have not experienced any acne in their lifetime.
Nechuta and colleagues used data
from the Shanghai Women's Health
Study, a large, population - based prospective cohort study of about 75,000 women ages 40 to 70, from Shanghai, China, led by Wei Zheng, MD, PhD, at the Vanderbilt Epidemiology Ce
Study, a large, population - based prospective cohort
study of about 75,000 women ages 40 to 70, from Shanghai, China, led by Wei Zheng, MD, PhD, at the Vanderbilt Epidemiology Ce
study of about 75,000 women ages 40 to 70,
from Shanghai, China, led by Wei Zheng, MD, PhD, at the Vanderbilt
Epidemiology Center.
The meta - analysis of findings
from 15
studies by the European Eye
Epidemiology Consortium found that around a quarter of the European population is short - sighted but it is nearly twice as common in younger people, with almost half (47 per cent) of the group aged between 25 and 29 years affected.
Researchers used data
from the two countries because they «are the world's two largest emitters of greenhouse gases and responsible for about one - third of global warming to date,» said Longjian Liu, M.D., Ph.D., lead
study author and an associate professor of
epidemiology and biostatistics at Drexel University in Philadelphia, Pennsylvania.
To investigate the issue, a team led by Tracey Weissgerber, PhD and Vesna Garovic, MD (Mayo Clinic) analyzed information on 919 men and 1477 women
from 954 sibships who participated in the Genetic
Epidemiology Network of Arteriopathy
study, which examined the genetics of hypertension in white, black, and Hispanic siblings.
This
study compared data
from the Surveillance,
Epidemiology and End Results Program (SEER) of the National Cancer Institute, a population - based registry collecting cancer incidence and survival data
from 18 geographic areas through the United States, with data
from the USIDNET registry.
Dr Lavinia Paternoster, Senior Lecturer in Genetic
Epidemiology from Bristol Medical School: Population Health Sciences, who initiated the
study, said: «This
study brought together two European birth cohorts, PIAMA,
from the Netherlands and ALSPAC (or «Children of the 90s»)
from Bristol.
Based on the results published in this paper, and with the aim to
study the biology and
epidemiology of Leishmania in a clinically more relevant context, Dr. Gerald Späth established the international consortium «LeiSHield», that coordinates a concerted effort between partner teams of the Institut Pasteur International Network and beyond, which was initially supported by a seeding fund
from the Institut Pasteur International Direction, and is now funded by a 1.7 million euro grant
from the EU H2020 program.
To use hd - PS, a researcher downloads the program
from the Harvard site, connects it to one of the data software packages widely used in
epidemiology, and imports to the system a wide range of health information on each
study subject, ranging
from basics like blood pressure and age to smaller, more esoteric factors like whether the individual saw a doctor in the past six months.
«This research is important because previous
studies have shown that a reduction in blood supply to the heart (ischemia) during mental stress doubles the risk of heart attack or death
from heart disease,» said Viola Vaccarino, M.D., Ph.D., senior author of the
study and professor of
epidemiology and medicine at Emory University's Rollins School of Public Health in Atlanta, Georgia.
A second, unrelated
study that analyzed data
from a cohort of people with type 1 diabetes in the Pittsburgh area, the Pittsburgh
Epidemiology of Diabetes Complications
study (EDC), showed why it is so important to recognize depressive symptoms in people living with diabetes: Those who exhibit the highest level of depressive symptoms are most likely to die prematurely.
«These data are very consistent with earlier findings
from EDC which showed that greater depressive symptomatology predicted the incidence of heart disease in this cohort,» said Trevor Orchard, MD, M.Med.Sci., FAHA, FACE, Professor of
Epidemiology, Medicine and Pediatrics at the Graduate School of Public Health, University of Pittsburgh, and the EDC
study principal investigator.
The
study is the result of a tight collaboration between the
Epidemiology and Public Health Research Unit at LIH's Department of Population Health and researchers
from LIH's Competence Centre for Methodology and Statistics, the University of Liège, the VU University Medical Centre in Amsterdam in the Netherlands, the University of Western Ontario in Canada and the Aarhus University in Denmark.
«The holy grail of depression
epidemiology is that we want to intervene early to prevent people
from having depressive episodes,» says social scientist Stephen Gilman of Harvard University, who was not involved in the
study.
Ride - hailing services reduce drunk - driving crashes in some cities, reports a new
study from researchers at the Perelman School of Medicine at the University of Pennsylvania this month in the American Journal of
Epidemiology.
«Metabolomics is now often used to accompany large genomic cohort
studies from biobanks, to correlate genotype and genomic variants with specific phenotypes, to complement nutritional
studies monitoring food components or endogenous metabolites, or to support measurements in
epidemiology studies,» says Andreas Huhmer, director of proteomics and metabolomics marketing at Thermo Fisher Scientific, headquartered in Waltham, Massachusetts.
To identify cases of encephalitis, the
study used data
from the Rochester
Epidemiology Project, a medical records database of all medical providers in Olmsted County, Minnesota.
Based on the results published in this paper, and with the aim to
study the biology and
epidemiology of Leishmania in a clinically more relevant context, Dr. Gerald Späth established the international consortium «LeiSHield» (www.leishield.org), that coordinates a concerted effort between partner teams of the Institut Pasteur International Network and beyond, which was initially supported by a seeding fund
from the Institut Pasteur International Direction, and is now funded by a 1.7 million euro grant
from the EU H2020 program.
This population
epidemiology study uses data
from a Japanese national registry to characterize trends in use of chest compression and defibrillation by bystanders and associated rates of neurologically intact survival among patients with out - of - hospital cardiac arrest.
The
study, publishing online January 18 in the American Journal of
Epidemiology, found elderly women with less than 40 minutes of moderate - to - vigorous physical activity per day and who remain sedentary for more than 10 hours per day have shorter telomeres — tiny caps found on the ends of DNA strands, like the plastic tips of shoelaces, that protect chromosomes
from deterioration and progressively shorten with age.
«Clinicians treating children with heart defects can help educate parents regarding infective endocarditis and its prevention, particularly in the highest risk groups identified in this
study,» said Dinela Rushani, co-author of the
study from the Department of
Epidemiology, Biostatistics and Occupational Health at McGill University.