The researchers conducted additional studies of the virus using brain tissue
from epilepsy patients and showed that the virus does not infect noncancerous brain cells.
Using a computer model based on direct brain recordings
from epilepsy patients, they are the first to show the existence of a network of neural regions that can push or pull on the synchronization of the regions directly involved in a seizure.
Not exact matches
Providing
patients and physicians with an accurate way to track and report seizures could lead to advancements in how care is provided for those who suffer
from conditions, such as
epilepsy — 3.4 million people in the US suffer
from the condition, according to a CDC estimate.
The governor wants any law to cover
patients suffering
from cancer,
epilepsy, Parkinson's disease, MS, HIV / AIDS, diabetics, and spinal cord injuries.
In a group of
patients who underwent surgery for
epilepsy, over half had stem cells where healthy individuals do not have them, according to a study
from Sahlgrenska Academy.
The phase III study was conducted among 366
patients with TSC and
epilepsy from 25 countries who were randomly assigned to either a placebo, a low dose of everolimus or a higher dose.
Kerr and his team accomplished this by inspecting outpatient clinical notes
from patients with medication - resistant seizure disorder, who were later diagnosed as having
epilepsy or non-epileptic seizure disorder, using the gold standard diagnostic assessment, 72 - hour in -
patient closed circuit video - electroencephalography (VEEG) monitoring.
I specialise in treating
patients with intractable
epilepsy, and we need EEG monitoring to see where the seizures are coming
from in the brain.
So far, researchers with the Allen Institute for Brain Science in Seattle have described the intricate shapes and electrical properties of about 100 nerve cells, or neurons, taken
from the brains of 36
patients as they underwent surgery for conditions such as brain tumors or
epilepsy.
«They may not look like a big deal
from the outside, but if you listen in to the brain of a
patient having one of these seizures, you can hear that the brain is in seizure,» says Josef Parvizi, a Stanford neuroscientist and
epilepsy specialist who developed the brain stethoscope with colleague Chris Chafe, a music researcher at Stanford.
When
patients with
epilepsy don't experience enough benefit
from current medications, doctors sometimes treat the disorder by surgically removing the area where seizures arise.
Further analysis including in tissues
from more
patients with other forms of
epilepsy also showed that CLOCK RNA and protein were often significantly lacking in both in excitatory and inhibitory neurons in affected brain regions.
Patients with epilepsy often have ECoG arrays temporarily implanted in their brains to determine the location in the brain of epileptic seizures, so the scientists were able to study all the data collected from five such patients on healthy, seizure - free
Patients with
epilepsy often have ECoG arrays temporarily implanted in their brains to determine the location in the brain of epileptic seizures, so the scientists were able to study all the data collected
from five such
patients on healthy, seizure - free
patients on healthy, seizure - free nights.
«In the long run, this improved understanding may enable the development of better treatment options for
patients suffering
from epilepsy.
Given how long it is likely to take for new medications against
epilepsy to be tested and approved, some experts argue that more
patients with relentless
epilepsy could benefit
from recent advances in surgical techniques and various methods for stimulating neurons in ways that make them behave less erratically.
«Applying these analysis concepts to multichannel long - term EEG recordings
from 17
epilepsy patients with high temporal resolution allowed us to derive a sequence of functional brain networks spanning several days in duration,» said Christian Geier, a doctoral student working with Lehnertz.
Here, the researchers examined brain functions of
patients suffering
from epilepsy by using methods that coincided with their medical treatment.
Then a frustrated group of
epilepsy physicians invited computer nerds around the world to take a shot instead, providing data sets recorded
from the brains of human
epilepsy patients and epileptic dogs.
Distinct
from epileptic seizures, IEDs can impair memory in
epilepsy patients.
The hope is to develop a neuroprosthetic that could not only help
patients with
epilepsy and TBI but also those suffering
from depression, anxiety, PTSD, and other neuropsychiatric disorders.
The researchers first analyzed a database of EEG recordings taken
from 16
patients who had already undergone surgery for
epilepsy.
What's really necessary, Dr. Gaillard says, is real data on efficacy for each of the medications commonly prescribed to pediatric
epilepsy patients — a marked vacuum in research that prevents doctors
from using evidence - based reasoning when making medication choices.
Loeb and colleagues used a technique called magnetic resonance spectroscopy to identify the metabolomic signature of epileptic versus non-epileptic brain tissues removed
from nine
patients who underwent invasive electrical brain monitoring as part of their
epilepsy surgery.
He explained that it's likely that these genes do not function properly during development in
patients suffering
from schizophrenia,
epilepsy, or other diseases.
Results
from an unexpected quarter is could help neurologists to identify which brain region to remove to eliminate an
epilepsy patient's symptoms.
Using brain data crowdsourced
from 22
epilepsy patients with implanted electrodes, researchers
from the University of Pennsylvania led by Danielle Bassett have developed a series of algorithms that can predict where in the brain a seizure will originate and which groups of neurons it will likely spread to as it grows.
Topamax, an
epilepsy drug
from Ortho - McNeil Pharmaceutical, has proven extremely effective on migraines in clinical trials: Half of all
patients have reported a 50 percent reduction in the frequency of migraines, and more than a quarter have a reported 75 percent reduction.
In the new paper, Sahin and colleagues took their observations to humans, studying Purkinje cells derived
from three
patients with TSC (two also had ASD symptoms, and all three also had
epilepsy).
The researchers used two types of data
from patients with temporal lobe
epilepsy and healthy control subjects.
In addition to cognitive problems,
patients with X-linked mental retardation (XLMR)-- which includes fragile x syndrome (ScienceNOW, 24 May 2007)-- may also suffer
from epilepsy, macrocephaly (an enlarged head), and reproductive defects.
Rice statistician Marina Vannucci and lead author Sharon Chiang, an M.D. / Ph.D. student at Rice and Baylor College of Medicine, and their co-authors detailed their technique to analyze brain activity data
from patients with
epilepsy and control groups to see how distinct structures in the brain spontaneously interact.
Working with Seattle, Washington — area neurosurgeons, the Allen Institute acquired healthy cells
from the cortex — the outermost layer of the brain that coordinates perception, memory, thoughts, and consciousness —
from patients undergoing surgery for
epilepsy or brain tumors.
A recent paper in the journal
Epilepsy & Behavior describes an
epilepsy patient who had electrodes implanted within her brain at Emory University Hospital, because neurologists wanted to understand where her seizures were coming
from and plan possible surgery.
To evaluate the efficacy of artisanal CBD for
patients with
epilepsy, Robert Carson, MD, PhD, and colleagues performed a retrospective study of medical records obtained
from Vanderbilt's BioVU resource.
In the study, they show how levetiracetam — a drug commonly prescribed for
patients who suffer
from epilepsy — suppresses abnormal brain activity and restores memory function in these mice.
Alzheimer's disease
patients may benefit
from using
epilepsy drugs.
The neurosurgeons at Penn Medicine's Center for Functional and Restorative Neurosurgery are leaders in breakthrough surgical treatments for
patients with movement disorders including Parkinson's disease, tremor
from multiple sclerosis or other causes, dystonia, and medically intractable
epilepsy.
In addition,
patients may benefit
from the advanced care provided by
epilepsy centers if they continue to have seizures despite treatment with two medications, experience unacceptable side effects or are pregnant or want to become pregnant.
For the trial, researchers enrolled 120 children
from 2 to 18 years old with Dravet syndrome, a rare genetic form of
epilepsy that kills up to 20 percent of
patients by the time they are 20.
For example, a study conducted in his own lab found that forebrain assembloids generated
from patients with Timothy syndrome — a genetic disease associated with autism and
epilepsy, showed abnormal migration of GABAergic neurons during the development of the cerebral cortex.
The most common form of focal
epilepsy is temporal lobe
epilepsy,
from which approximately 600,000
patients suffer chronically in Europe alone.
Although it is often suggested that children with
epilepsy who are benefiting
from ketogenic dietary therapy continue this for at least two years, duration of treatment could be shorter in
patients with infantile spasms who become seizure - free; one study reported no adverse effect on seizure outcomes and less risk of growth disturbances when treatment was tapered down after 8 months (15).
It is important to understand that not only
epilepsy patients benefit
from this type of diet.
As such, for example, it would not be appropriate for a
patient that suffers
from epilepsy.
A 2006 study revealed that up to 30 percent of
patients who actually suffer
from psychogenic nonepileptic seizures (PNES) are misdiagnosed with
epilepsy [source: ScienceDaily].
Long - term outcomes
from the PEARLS randomized trial for the treatment of depression in
patients with
epilepsy