Cancers can be divided into three general groups: carcinomas that arise
from epithelial cells that cover the body (skin) or line internal body surfaces; sarcomas that begin in connective, skeletal, muscular, or reproductive tissues; lymphomas that invade the lymph nodes and the lymphatic system.
In puppyhood the buds of t he permanent teeth are still developing (
from epithelial cells).
In puppyhood the buds of the permanent teeth are still developing
from epithelial cells.
Originating
from epithelial cells (skin cells that cover the lining of body surfaces), Carcinomas can occur on the skin, bladder wall, and blood vessels that then pass into the surrounding tissues and organs.
Upon insult to the intestine, zonulin is released
from epithelial cells, where it can act locally on receptors on the apical (lumen - facing) membrane of nearby cells.
Carcinomas arise
from epithelial cells, and tumor progression involves a loss of polarity, so an understanding of cell polarity is important in the identification of novel therapeutic approaches to cancer.
Most types of cancer arise
from epithelial cells.
Cancer cells can also migrate collectively
from epithelial tumors by wrapping around vessels or muscle fibers.
MimEX ™ Tissue Model Systems provide a robust system to generate accessible ex vivo 3 - D tissue
from epithelial - derived organs.
«It is an important physiological mechanism for the ordered removal of cells
from the epithelial layer, but when it is out of control has profoundly damaging effects,» said Campos.
Gut microbiota that live in the outer regions of the mucus and remain a safe distance
from epithelial cells provide a benefit to the host, but Chassaing and Gewirtz hypothesize that microbiota that encroach upon host cells drive chronic inflammation that interferes with the normal action of insulin, promoting type 2 diabetes.
Previous studies have shown that MMP9 derived
from epithelial cells plays a protective role in the development of CAC.
But the pH - responsiveness also allows the bacterium to escape a certain death by detaching
from epithelial - and mucus cells that are shed into the gastric juice,» says Jeanna Bugaytsova, researcher at Department of Medical Biochemistry and Biophysics and first - author of the article.
Not exact matches
The use of hydrogels dressings is a concept stolen
from disciplines such as geriatrics, where patients suffer bed wounds and these water - based polymer matrix dressings are applied to maintain moisture, inhibit scab or crust formation, reduce pain, and enhance
epithelial migration for wound repair.
Transient Silencing of 14 -3-3sigma promotes proliferation of p63 - positive progenitor cells isolated
from human breastmilk in mammary
epithelial cell culture.
If they succeed, they can be reasonably confident that
epithelial cells can be taken
from a patient and used to regenerate damaged tissue in that same person.
The mechanisms that promote or enable drug resistance include drug inactivation, drug target alteration, drug removal
from cells, DNA damage repair, cell death inhibition and the
epithelial - mesenchymal transition (EMT) that enable solid tumors to transform into more metastatic grades.
They concluded
from that evidence that these specialized RNAs were coming
from two types of
epithelial cells that line the GI tract.
Their sight deteriorates
from around age 6 when retinal pigment
epithelial cells (RPEs) start to die off rapidly, possibly due to a defective gene.
The researchers performed genome - wide analysis of nasal
epithelial cells collected
from children experiencing acute asthma exacerbation.
The multinational research group utilized a model system where human retinal pigment
epithelial cells were infected with Zika virus strain they isolated earlier
from fetal brain [T1].
Departing
from prior studies, the team collected
epithelial cells and fibroblasts
from human sources: one cadaver and four living people who had their healthy voice boxes removed during unrelated surgeries.
In some instances, however, the flu virus can prevent the macrophages
from carrying out their protective function, allowing the
epithelial cells to become vulnerable to infection.
To capture uncommon genetic variants, the study used an exome genotyping array to genotype 7,060
epithelial ovarian cancer (EOC) cases and 6,712 cancer - free women
from the Ovarian Cancer Association Consortium.
«But what we've now shown is that RSV has an increased ability to cause airway obstruction because, during an RSV infection, the virus expresses a specific RSV - encoded non-structural protein, or NS2, in
epithelial cells, causing the cells to shed
from the airway lining and into the airway lumen.
Kang found Korean red ginseng extract improved the survival of human lung
epithelial cells against RSV infection and inhibited the virus
from replicating, or multiplying, in the body.
Bottom: Human
epithelial cells
from breast tissue showing the effects of endoplasmic reticulum stress (blue) which fills the entire cell structure.
Researchers at the RIKEN Center for Developmental Biology in Kobe plan to generate replacement retinal pigment
epithelial cells
from iPS cells generated
from patients suffering age - related macular degeneration.
The images show how a growth factor caused cells to change forms and regroup
from tight packs of
epithelial cells to more mobile, loose arrays of mesenchymal cells — information useful for studying cancer and wound healing.
The cell changes, known as an
epithelial to mesenchymal transition, or EMT, are normal and helpful during wound healing, but problematic when cancer cells spread
from the primary tumor site to other sites in the body.
Researchers
from the University of Michigan and the Mayo Clinic studied rat IEC - 6 intestinal
epithelial cells, chosen because they maintain a stable diploid genomic structure (two sets of chromosomes), lack the cellular characteristics of cancer cells, and replicate normally.
In the study, the protein Miro1 was shown to regulate the transfer of mitochondria
from mesenchymal stem cells to
epithelial cells.
Basically, when you look at different types of cells, such as fibroblasts, which form connective tissue, or
epithelial cells,
from saliva, you see general correlations within a person.
He and his colleagues will inject into patients» eyes retinal pigment
epithelial cells that ACT derived
from hES cells.
The goal of the first experiment was to see whether lncRNAs are differentially expressed in prostate cancer by measuring total RNA
from prostate cancer cell lines and normal
epithelial prostatic cells using NCode human ncRNA array and SurePrint G3 human lncRNA microarrays.
A trio of researchers
from the Perelman School of Medicine at the University of Pennsylvania and Children's Hospital of Philadelphia (CHOP) found mutations in a master - switch protein called
Epithelial Splicing Regulatory Protein 1 (ESRP1) in individuals with SNHL.
But airway
epithelial cells contain both molecules at all times, so researchers wondered what keeps healthy tissues
from growing out of control.
In search of early markers of lung cancer, pulmonary and critical care physicians Avrum Spira and Jerome Brody of the Boston Medical Center sampled bronchial tube
epithelial cells
from 85 people.
The effects of consuming emulsifiers were eliminated in mice devoid of microbiota (germ - free mice), and transplanting microbiota
from emulsifier - treated mice to germ - free mice was sufficient to transfer alterations in intestinal
epithelial cells» homeostasis, suggesting a central role played by the microbiota in tumor development.
Microscopic images show that RMC - 1 prevented FOXM1
from entering the nucleus in cultured human airway
epithelial cells and in mouse allergen - sensitized respiratory airways.
The study team assessed three sets of outcomes: a maturational index (MI) based on
epithelial cells
from the children's urogenital tissue; ultrasound measurements of uterine, ovarian and testicular volume, as well as breast - buds; and hormone concentrations seen in blood tests.
They removed
epithelial cells
from the fourth mammary gland of each mouse, leaving behind the stromal tissue.
Our first results demonstrate our ability to produce retinal precursors (even at a low yield) and mainly Retinal Pigment
Epithelial (RPE) cells at a high yield (99 %)
from hES and iPS cells.
In addition to his studies of
epithelial polarity, Dr. Goldenring also studies the mechanisms responsible for the development of pre-neoplastic lineages
from metaplasias in the stomach and their roles in gastric carcinogenesis.
This is a scanning electron microscope image of retinal pigment
epithelial cells derived
from stem cells.
His recent published work describes the rescued visual function in animals using retinal pigment
epithelial cells derived
from human embryonic stem cells and a method for deriving stem cells using a single - cell approach that does not harm embryos.
The results of a typical experiment are shown in Figure 3 and demonstrate that even though spleen cells
from CD4 KO mice could adoptively transfer corneal allograft rejection, they did not display conventional CTL activity against either BALB / c corneal
epithelial or endothelial cells.
The virulence effects of H pylori have been shown to derive
from bacterium factors causing alterations in gastric
epithelial cells.
However, in vitro assays using spleen cells
from CD4 KO mice that had rejected BALB / c corneal allografts failed to detect CTL activity against donor corneal
epithelial or endothelial cells.
Human corneal
epithelial cells (HCEP), by comparison, readily divide
from a source of cells outside the cornea.