Cancer cells can also migrate collectively
from epithelial tumors by wrapping around vessels or muscle fibers.
Not exact matches
The mechanisms that promote or enable drug resistance include drug inactivation, drug target alteration, drug removal
from cells, DNA damage repair, cell death inhibition and the
epithelial - mesenchymal transition (EMT) that enable solid
tumors to transform into more metastatic grades.
The cell changes, known as an
epithelial to mesenchymal transition, or EMT, are normal and helpful during wound healing, but problematic when cancer cells spread
from the primary
tumor site to other sites in the body.
The effects of consuming emulsifiers were eliminated in mice devoid of microbiota (germ - free mice), and transplanting microbiota
from emulsifier - treated mice to germ - free mice was sufficient to transfer alterations in intestinal
epithelial cells» homeostasis, suggesting a central role played by the microbiota in
tumor development.
More important, by introducing miR - 200, they managed to activate production of E-cadherin protein and reverse
tumors from a more - invasive mesenchymal into a less - invasive
epithelial form.
Carcinomas arise
from epithelial cells, and
tumor progression involves a loss of polarity, so an understanding of cell polarity is important in the identification of novel therapeutic approaches to cancer.
TCC is a malignant
tumor that develops
from the transitional
epithelial cells that line the bladder.
Mammary gland
tumors can be either malignant (cancerous) or benign (non-cancerous) and arise
from the different types of tissues (
epithelial or glandular tissues, and mesenchymal or connective tissues) in the mammary gland.