Sentences with phrase «from flaviviruses»

This is the first structure of any helicase bound to ATP from flaviviruses, a group including other well - known pathogens such as dengue, yellow fever, and West Nile viruses.

Not exact matches

Unfortunately, many other viruses from the same family, known as flaviviruses, have similar versions of NS1 and can produce a false positive.

The scientists suggest that flavivirus helicases could have evolved a conserved motor to convert chemical energy from nucleoside triphosphate to mechanical energy to unwind their genetic material, but the motors of the flaviviruses move in distinct ways to access their genomic RNA.

«Most flaviviruses are zoonotic,» meaning they can be transmitted from animals to people, Gao says, «so infection of human beings can not be ruled out.»

Assays already exist to detect Zika virus infection, but they either work only shortly after infection or are poor at differentiating Zika from other flaviviruses.

The assay was implemented in five countries and tested using a large number of clinical samples from travelers and patients living in areas with a high level of exposure to Zika virus and other flaviviruses.

«These results support that the antibody - based assay that we have developed is highly effective in detecting both recent and past Zika virus infections and in discriminating Zika from other flavivirus infections,» said Davide Corti, senior vice president and chief scientific officer of Humabs BioMed.

Zika and dengue are closely related and come from the same family of viruses, known as flaviviruses.

The viruses» genetic similarity makes it possible to substitute a gene in one flavivirus's genome with the equivalent gene from another, creating a functional but nonpathogenic virus called a chimera.

A new research study from University of North Carolina researchers shows that individuals who have been previously infected with a flavivirus — specifically dengue and Zika viruses — could have antibodies that protect against Zika.

Shannon entropy analysis of the NS5 polymerase mature protein revealed that a G374E mutation, in a region that contributes to interferon resistance in other flaviviruses by interfering with JAK - STAT signaling was present in both the Asian and American sequences from the 2007 - 2008 Venezuelan outbreak, but was absent in the sequences from the 2001 Venezuelan outbreak.

From preliminary epidemiology, pathogen isolation, and reproduction of the clinical disease by the isolated virus, BYDV, Koch's postulates were fulfilled, and a new flavivirus causing a serious duck disease was identified.

We performed a systematic investigation, from epidemiology, pathogen isolation, virus characterization, disease reproduction by infection with the isolated virus (fulfilling Koch's postulates), to virus genome sequencing and found that the duck egg drop disease was caused by a new flavivirus, BYD virus, that is closely related to Tembusu virus.

The current test suffers from cross-reactivity and a lack of precision in areas where DENV or other flaviviruses may coexist.

What we learn from WNV may prove useful in the development of novel therapeutics for WNV and other more serious or newly emerging flaviviruses.