Not exact matches
For this study, Nakano and his collaborators used cancer
cells from 40 patients with high - grade
gliomas, focusing on tumor
cells with a stem -
cell signature.
Gαs went
from lipid rafts to nonraft regions of the plasma membrane in the
glioma cells, which enhanced its signaling ability.
Nakano says UAB will be the only site in the Deep South for this unique trial aimed at a molecular target in
glioma stem
cells, a target that is different
from the ones described in the Cancer Research paper.
There are different types of
glioma, classified according to an established system based on which
cell type the tumor arises
from.
The most common primary, malignant brain tumors in adults, called
glioma, are formed
from cells in the brain that are not nerve
cells.
«We showed that the probe is equally capable of detecting invasive cancer
cells from all grades of invasive
gliomas,» says Dr. Petrecca.
«Inhibition of the EZH2 pathway slows growth of tumors in mouse brain derived
from glioma stem
cells from the enhancing margin of human tumors.
A research team led by Christine Brown, Ph.D., and a clinical team headed by Behnam Badie, M.D., has received a $ 12.8 million grant
from the CIRM to fund a phase 1 chimeric antigen receptor (CAR) T
cell trial targeting an aggressive brain cancer called malignant
glioma, which includes glioblastoma.
Reykjavik, ICELAND, 25 September 2011 — Scientists at deCODE Genetics and academic collaborators
from Iceland, The Netherlands, Spain, Denmark, Germany, Sweden, the USA, the UK and Romania today report the discovery of a variant in the sequence of the human genome associated with risk of developing basal
cell carcinoma of the skin (BCC), as well as prostate cancer and
glioma, the most serious form of brain cancer.
Molecular testing: Some primary brain tumors, including some of the most common types of
gliomas, are defined by their key molecular features resulting
from tumor
cell mutations.
U-M's internationally renowned Translational Neuro - Oncology Laboratory generates novel primary
cell cultures
from pediatric and adult
glioma tissue samples to study mechanisms of
glioma growth and targeted treatment response.
There, they will be exposed to tumor antigens released
from dying
glioma cells through TK + valacyclovir - induced
glioma cell death, and thus mediate a specific anti-malignant
glioma immune response against remaining malignant
glioma cells.
Gliomas are brain tumors that arise
from glial
cells, which help nerve
cells to stay connected and send signals throughout the body.
Gliomas arise
from the supporting
cells of the brain (glial
cells) and include astrocytomas and oligodendrogliomas.
Glioma - These tumors arise
from the supporting
cells of the brain and include astrocytomas, oligodendrogliomas, glioblastoma multiforme and ependymomas.