Sentences with phrase «from high sequencing»

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In fact, wherever you find life on Earth, from boiling hot vents deep under the sea to frozen bacteria in the clouds high above the planet, you find this sequence.

Rats with high blood pressure benefited from a long - term diet rich in capsaicin, which gives the heat to hot peppers and starts a chemical sequence that relaxes blood vessels.

The data suggest that the brain does not develop in a sequence from simplest systems (e.g., vision, motor) to more complex high - order systems, but perhaps instead first develops the areas that will be most critical in bridging across systems.

This month the polar sequence, which never sets as seen from the United States and Canada, stands highest and most prominent.

Through a variety of «high tech» approaches, including the isolation of monoclonal antibodies from single B cells and ultra-deep sequencing of shifting viral populations over more than three years of infection, the researchers studied one woman who developed potent broadly neutralizing antibodies.

«For chloroplast genome recovery from total DNA sequence data, the deliberate identification of reads that represent chloroplast DNA inserts into the nuclear genome allowed us to attain a higher - quality chloroplast genome assembly in a time - and cost - effective way,» Garaycochea explains.

HPV is detected using a DNA analysis that looks for characteristic sequences from the 13 high risk strains of the virus in the cervical cell sample.

Christina Warinner and Cecil M. Lewis, Jr., professors in the Department of Anthropology, OU College of Arts and Sciences, collaborated with researchers from Arizona State University and Pennsylvania State University on the capture, enrichment and high - throughput sequencing of DNA extracted from six individuals at the 700 - year - old Oneota cemetery, Norris Farms # 36.

The kids then checked the sequences against the database at barcodinglife.org The high schoolers found everything from pigeons and Pomeranians to an invasive latrine fly and what looks to be at least a new subspecies of cockroach.

A new high - coverage DNA sequencing method reconstructs the full genome of Denisovans — relatives to both Neandertals and humans — from genetic fragments in a single finger bone

«Applying these analysis concepts to multichannel long - term EEG recordings from 17 epilepsy patients with high temporal resolution allowed us to derive a sequence of functional brain networks spanning several days in duration,» said Christian Geier, a doctoral student working with Lehnertz.

When they sequenced the iPS cell lines, they found higher numbers of mitochondrial DNA mutations, particularly in cells from patients older than 60.

In 2010 the team discovered a new kind of human, cousins to Neanderthals called Denisovans, by sequencing DNA from a 50,000 - year - old pinkie finger found in a high - altitude Siberian cave in Denisova.

Three research groups sequenced high - quality genomes of 787 people from over 270 populations.

The team of researchers examined the hydroclimatic and societal impacts in Egypt of a sequence of tropical and high - latitude volcanic eruptions spanning the past 2,500 years, as known from modern ice - core records.

Scientists at the University of Maryland have developed a new, web - based tool that enables researchers to quickly and easily visualize and compare large amounts of genomic information resulting from high - throughput sequencing experiments.

In vitro experiments and high - throughput RNA sequencing revealed that CTCF deletion profoundly altered the B lymphocyte transcriptional program, shifting cells from a gene expression profile typical of the germinal center to one more similar to that seen in plasma cells.

The most concerning finding was from the «high - efficiency particulate arrestance» (HEPA) air filter used in the ISS: 99.65 % of the viable sequences they retrieved came from Actinobacteria, which, at most, accounted for only 25.25 % of the viable sequences found in the JPL clean room vacuum bags.

From these efforts, we identified a high - quality orthologous gene set across avian species, consisting of exons from 8251 syntenic protein - coding genes (~ 40 % of the proteome), introns from 2516 of these genes, and a nonoverlapping set of 3769 ultraconserved elements (UCEs) with ~ 1000 bp of flanking sequenFrom these efforts, we identified a high - quality orthologous gene set across avian species, consisting of exons from 8251 syntenic protein - coding genes (~ 40 % of the proteome), introns from 2516 of these genes, and a nonoverlapping set of 3769 ultraconserved elements (UCEs) with ~ 1000 bp of flanking sequenfrom 8251 syntenic protein - coding genes (~ 40 % of the proteome), introns from 2516 of these genes, and a nonoverlapping set of 3769 ultraconserved elements (UCEs) with ~ 1000 bp of flanking sequenfrom 2516 of these genes, and a nonoverlapping set of 3769 ultraconserved elements (UCEs) with ~ 1000 bp of flanking sequences.

They used high - throughput gene sequencing to identify individual microbiomes in each of nearly 700 samples of must and wine, collected in 2011 from eight stages of the fermentation process.

The researchers examined the DNA of bacteria from freshwater biofilms from the terrestrial regions of the Arctic and Antarctica using high - throughput sequencing.

The cell - free DNA extracted from the plasma and, separately, the genome of white blood cells were then sequenced using the high - intensity, 508 - gene sequencing assay.

This innovative approach — using high - intensity sequencing to detect cancer from circulating tumor DNA in the bloodstream — heralds the development of future tests for early cancer detection.

Xuanmin Guang, project manager from BGI, said, «Minke whale is the first marine mammal that has been sequenced with such high - depth genome coverage.

Researchers from BGI reported the most complete haploid - resolved diploid genome (HDG) sequence based on de novo assembly with NGS technology and the pipeline developed lays the foundation for de novo assembly of genomes with high levels of heterozygosity.

However, relatively few sequences have been determined from patients in Liberia, even though this country had the highest number of Ebola - related deaths,» says senior study author Gustavo Palacios of the U.S. Army Medical Research Institute of Infectious Diseases (USAMRIID).

Thus, this study has implications for analysis of human vaccine studies, as in addition to searching for defined lineages it is worthwhile to perform functional analysis of monoclonal antibodies that may have found new structural solutions to high affinity binding which can not be discerned from DNA sequence alone.

The study broke new ground in other areas as well, yielding the first ancient whole genomes of East Asian ancestry and the highest coverage ancient human genome from Asia (7x coverage) sequenced to date.

These should involve basic and applied biologists, including those with expertise in microorganisms or in higher organisms; informaticians and mathematicians, who can develop methods that extract information from the mountains of sequence data; and chemists, physicists and engineers.

Our findings are in agreement with a recently published study by Oskarsson et al. (2015) in which Tg mice injected through the tail vein with in vitro — generated aggregates from synthetic peptides containing the sequence of IAPP developed a higher percentage of IAPP aggregates in the pancreas than did untreated controls when subjected to a high - fat diet.

The poor apparent coverage was the result of high sequence divergence of the TMAdV genome from SAdV - 18, which hindered the identification of most of the 16,524 actual deep sequencing reads derived from TMAdV (Fig. 2B, red).

In parallel, we use high throughput sequencing methods to obtain both deep phylogenetic rDNA / rRNA tag data and metagenomic and metatranscriptomic functional profiles from size fractions covering the entire plankton community from viruses to fish larvae (Figure 2B and 2C).

The unusually high death rate (83 %) makes titi monkeys unlikely to be natural hosts for TMAdV, and the genomic sequence of TMAdV revealed that it is very different from any other known adenovirus.

-- In silico basic and systems biology: We develop innovative approaches to reverse engineer biological networks from omics data, model tumor progression at the genomic, transcriptomic and epigenetic level, automatically annotate new proteins and functional elements through integration of complex and heterogeneous data, including data obtained from high - throughput sequencing or time - lapse video - microscopy.

«One insight we gained from this high resolution sequence data is that later in the outbreak, there was very little cross-border exchange of the virus,» said lead author Danny Park.

Following the isolation and purification of microbial DNA from all samples, we used community fingerprinting (ARISA) and high - throughput sequencing of the 16s ribosomal RNA gene (V1 - V3) to describe the microbial community structure in each group.

However, the high costs of sample preparation for high - throughput next generation (NGS) sequencing have prevented laboratories from using these methods for routine processes like plasmid validation.

To avoid including reads sequenced from regions of the nuclear genome sharing high similarity with mitochondrial DNA (NUMTs), reads that did not map uniquely to the mitochondrial genome were discarded using SAMtools [32, 33].

A group of scientists from the United States, Sweden, Canada, and the UK, has sequenced and analyzed the complete high - quality genomes of two woolly mammoths...

Development of a high - throughput sequence - independent amplification strategy for dsRNA viruses will increase our ability to sequence more diverse rotavirus strains, including clinical isolates from both humans and animals, regardless of their nucleotide sequence diversity.

A research project launched today will blend the muscle of a huge Chinese genome sequencing center with the funding prowess and ambition of a high - profile American advocacy group, to create the world's largest library of sequenced genomes from people with autism.

High - Quality Draft Genome Sequence of Low - pH - Active Veillonella parvula Strain SHI - 1, Isolated from Human Saliva within an In Vitro Oral Biofilm Model.

This science project was adapted from the East Bay Biotechnology Education Program's High School Chloroplast Sequencing Project: Panico, E., Rosenbaum, S., and Shellem, B. (n.d.).

When scientists at the University of Delhi in India took soil samples from a pesticide dump and compared them with samples from a cleaner control site, they reported that the soil from the waste site contained a higher concentration of gene sequences from certain bacterial groups, such as Pseudomonas, Novosphingobium and Sphingomonas, that are known to degrade common pesticides like hexachlorocyclohexane.

Ultimately, I landed a job in the Medical Genomics Group, charged with the analysis of sequencing data from our high - throughput pipelines.

The early evolution of high - mass stars is similar; the only difference is that their faster overall evolution may allow them to reach the main sequence while they are still enshrouded in the cocoon of gas and dust from which they formed.

Using high - throughput DNA sequencing techniques, the research team looked at these functional elements in more than 1,000 data sets produced from over 100 mouse cell types and tissues.

Applying high - throughput sequencing technologies to obtain sequences from most of the genome, we calculated that the passenger pigeon's effective population size throughout the last million years was persistently about 1/10, 000 of the 1800's estimated number of individuals, a ratio 1,000 - times lower than typically found.

Results from studies with human cells showed highly reproducible expression levels, comparable with those determined by high - throughput RNA sequencing (RNA - seq).