Sentences with phrase «from human adenoviruses»
Furthermore, severe infections from human adenoviruses are more commonly associated with older age, immunosuppression, and chronic underlying conditions such as kidney failure [4], [41].
http://journals.plos.org/ Not exact matches
«No data from humans vaccinated with adenovirus 5 vectors are described in this paper,» says one of them, Dan Barouch of the Beth Israel Deaconess Medical Center at Harvard Medical School.
Adenovirus 5 has 50 or so known relatives that infect humans and so in principle could also be used as a basis for vaccines, as could one from a chimpanzee.
The work skirts a problem that has cropped up in experimental vaccines made from a similar human adenovirus — they don't work if you've already been exposed to the natural virus.
Erlacher and colleagues isolated HSCs from mice and infected them with a genetically engineered adenovirus that transiently produces a human protein called BCL - XL that inhibits BIM and BMF.
Now, a new report confirms that the Davis outbreak was the first known case of an adenovirus jumping from monkeys to humans.
Adenoviruses, first isolated in the 1950s from explanted adenoid tissue, are double - stranded nonenveloped DNA viruses that naturally infect many vertebrates, including humans and nonhuman primates.
The significant overall sequence divergence of TMAdV from known human and simian adenoviruses is highlighted by the finding that PAdV - A (porcine adenovirus A), a non - primate mammalian adenovirus, shared only a slightly less similar whole - genome pairwise identity to TMAdV of 47.0 % (Fig. 4).
After removal of similar viral genomes, bootscan plots of the whole genome and individual genes from a subset representing human / simian adenoviruses in species A — G and all non-primate vertebrate adenoviruses were generated.
However, recent serological surveys have found antibodies to New World and Old World monkey adenoviruses in donor human sera from regions where the monkeys are endemic [14], [15].
Normal translation of human adenovirus mRNA in cell - free lysates prepared from abortively as well as productively infected monkey cells
Additional experiments using RNA isolated from stocks of viruses from different virus families showed no cross reactivity of the assay with influenza A virus, influenza B virus, rhinovirus, human coronaviruses 229E, OC43, and NL63, and adenovirus (data not shown).