Sentences with phrase «from human lung»

In the first of the two new studies, Lobo and his team showed that they could obtain lung spheroid cells from human lung disease patients with a relatively non-invasive procedure called a transbronchial biopsy.

They turned to cultured cells derived from human lung tumours.

The researchers simulated alcohol vapor coming from a human lung by evaporating a water solution of alcohol of an appropriate concentration and at an appropriate temperature.

Not exact matches

By printing multiple lung airways — or any other afflicted organ — from a human patient and testing drugs on them, pharma companies can bypass the ethically challenged practice of testing on animals and proceed to human clinical trials with greater confidence the drugs will actually work, according to Wadsworth.

The study drew data from the Pregnancy Outcomes and Community Health (POUCH) and POUCHmoms studies, which were funded by the National Institute of Child Health and Human Development and the National Heart, Lung, and Blood Institute.

Using a mathematical model known as the Ising model, invented to describe phase transitions in statistical physics, such as how a substance changes from liquid to gas, the Johns Hopkins researchers calculated the probability distribution of methylation along the genome in several different human cell types, including normal and cancerous colon, lung and liver cells, as well as brain, skin, blood and embryonic stem cells.

Scientists have long experimented with organs - on - chips: tiny representations of human organs, such as lungs, hearts and intestines, made from cells embedded on plastic about the size of a computer memory stick.

Potti and his colleagues began by testing chemotherapy drugs on cultured cell lines from human tumors, such as from the lung, breast, or ovary.

Professor Heiner Boeing, also from the German Institute of Human Nutrition, added, «In addition to the many noted benefits for cardiovascular health, and risk of lung disease and cancer, it is clear that dental health is yet another reason not to take up smoking, or to quit smoking now.»

In their latest study, they tested compounds against cells from nine different types of human cancer, including common types affecting blood, colon, breast, prostate, ovaries, kidneys, and lungs.

The scientists also studied lung tissue from humans with asthma and healthy controls.

As Paul Rozin, often called the «father of the psychology of disgust», has pointed out, we live in a world where the air we breathe comes from the lungs of other people, and contains molecules of animal and human faeces.

We've also found that in a petri dish, the anti-quorum-sensing molecule prevents Pseudomonas from killing human lung cells and from making a biofilm that would enable it to mount an attack.

Their major hurdle: to come up with a replacement for hemoglobin (an iron - enriched protein in red blood cells that transports oxygen from the lungs to the rest of the body) that can be directly introduced into the human circulatory system.

Virologist Yoshihiro Kawaoka of the University of Wisconsin and University of Tokyo and his colleagues tested strains of H5N1 isolated from respiratory tissue in the noses, throats and lungs of infected humans.

They found out that TiY is capable of distinguishing TICs from non-TICs in various human lung cancer cell lines and patient - derived lung tumors.

Beyond lung cancer, TiY is able to target TICs in 28 types of human cell lines derived from the central nervous system, melanoma, breast, renal, ovarian, colon, and prostate cancer.

Contributing to the work were researchers from the National Human Genome Research Institute (NHGRI), the National Institute of Allergy and Infectious Diseases, the National Institute of Arthritis and Musculoskeletal and Skin Diseases, the National Heart, Lung, and Blood Institute and the NIH Clinical Center, all part of NIH, along with their colleagues in Turkey and the United Kingdom.

Although the organoids don't grow enough to replicate entire human organs, these mini-versions can mimic the 3 - D cellular infrastructure of everything from our guts to our lungs.

In recent years, several groups of scientists have grown lung cells from human iPSCs, but the recipes aren't perfect — the resulting lung cells grow amidst a jumble of liver cells, intestinal cells, and other tissues.

Now, scientists at Boston University's Center for Regenerative Medicine (CReM) have announced two major findings that further our understanding of this process: the ability to grow and purify the earliest lung progenitors that emerge from human stem cells, and the ability to differentiate these cells into tiny «bronchospheres» that model cystic fibrosis.

This tiny chip made from a polymer and loaded with human cells is designed to serve as a miniature replica of a human lung.

One postdoc presents data on her efforts to develop an organoid model for small - cell lung cancer; another reports progress on culturing hormone - secreting organoids from human gut tissue.

In the human voice box, or larynx, air from the lungs is pushed past the vocal cords, which then start moving back and forth sideways like a flag fluttering in the wind.

Published in the Journal of Clinical Investigation, the study collected metabolic data directly from more than 120 human lung cancer patients.

Kang found Korean red ginseng extract improved the survival of human lung epithelial cells against RSV infection and inhibited the virus from replicating, or multiplying, in the body.

The team also found that antibodies to human surfactant proteins called SP - A and SP - B reacted with proteins taken from the fish, implying that both use the same «anti-glue» to keep their lungs open.

In the second study in Science, researchers from Harvard University in Boston, Massachusetts, created a chip 1 to 2 centimeters long in which a 1 millimeter - wide channel, coated with human lung cells on the inside and overlaid with human blood capillaries on the outside, mimicked the air sacs, or alveoli, of the lungs.

They also hope to use what they learn from simple models of different tissue types to ultimately build functional human tissues like lung and kidney and neural circuits using larger - scale techniques.

«We have also tested this process in human cells taken from diseased lung tissue, and we see very similar results.»

In a letter published in the cancer journal Annals of Oncology, researchers led by Professor Jean - Philippe Spano, head of the medical oncology department at Pitie - Salpetriere Hospital AP - HP in Paris, France, report that while treating an HIV - infected lung cancer patient with the cancer drug nivolumab, they observed a «drastic and persistent decrease» in the reservoirs of cells in the body where the human immunodeficiency virus (HIV) is able to hide away from attack by anti-retroviral therapy.

Wiedinmyer wondered if this burning waste could be an underappreciated source of air pollutants, from greenhouse gases like carbon dioxide to tiny particles and toxic chemicals that can harm human lungs.

It is surprising to find that a single gene (ESRP), through its ancestral biological role (cell adherence and motility) has been used throughout the animal scale for very different purposes: from the immune system of an echinoderm to the lips, lungs or inner ears of humans,» states professor Jordi Garcia - Fernàndez, of the University of Barcelona's Department of Genetics, Microbiology and Statistics and the IBUB.

Influenza is thought to spread among humans three ways — touch; coughing and sneezing, which launches droplets containing virus from the lungs onto surfaces; and aerosols, smaller droplets suspended in the air that could be inhaled (SN: 6/29/13, p. 9).

«For example, mouse mammary tumors shared a signaling pathway that is found in human lung cancer and controls how cells reproduce and move from one location to another.»

M. bovis has also been isolated from humans only suffering from tuberculosis of the lungs and this may suggest that the bacterium is transmitted between people and not just between cattle and humans.

Abstract from the ASHG meeting Center for Human Genomics at Wake Forest University School of Medicine Nancy Cox's lab Web page Facts about Asthma from the American Lung Association

Human flu viruses preferentially bind to what are known as α 2,6 galactose receptors, which populate the human respiratory tract from the nose to the lHuman flu viruses preferentially bind to what are known as α 2,6 galactose receptors, which populate the human respiratory tract from the nose to the lhuman respiratory tract from the nose to the lungs.

This work was supported in part by grants from the US National Institute of Neurological Disorders and Stroke (R01NS058529), the National Human Genome Research Institute (U54HG003273), a joint NHGRI / National Heart Blood and Lung Institute grant (U54HG006542) to the Baylor Hopkins Center for Mendelian Genomics, and the BCM Intellectual and Developmental Disabilities Research Center, IDDRC Grant Number 5P30HD024064 - 23, from the Eunice Kennedy Shriver National Institute of Child Health and Human Development.

In this collaborative study, Wilkinson and Yanjun Lu, PhD, at the Tongji University in China, and their research teams compared human lung IMT samples and normal lung tissue samples from the same patients.

Further research will be needed to better understand the potential role of lung infection in Ebola and whether it may be a factor in transmission of the virus from one human to another.

Recently, our laboratory discovered that fungi secrete sugars that can act as a glue in order to help fungi attach to human lung cells and hide from the immune system during lung infections.

«The virus found in Betty was one that looked like it came from a human, and the level of virus in the lung was comparable to what we see in children.»

IHC - P mouse tumor tissue (from lung) with human cell line injected, some muscle tissue attached as well sees high background for human cellswith priamry Ab as well as isotype ctrl, but also for muscle (does not contain any EGF) Ab: 1 ug /...

Recent work from Fousteri Lab revealed a novel metabolic function of active transcription that is rapidly switched on globally in human cells to promote genetic accuracy, and reduce the mutation burden in genotoxins - exposed tissues, such as skin and lung, thus actively participating in lowering oncogenesis.

In this fashion, they derive a signal from the tumor cells proportional to tumor mass which arises spontaneously in vivo in the accurate setting of the lung and from the accurate genetic lesions found in human non-small cell lung cancer (NSCLC).

A study from Dr. Dusty Miller's laboratory indicates that Jaagsiekte sheep retrovirus (JSRV) infects both sheep and human cells cultured outside the body and does so by attaching to a receptor on the surface of lung cells.

«The most important application of this patent will be the use of our patented human endoderm cells to screen for agents that potentially affect endoderm differentiation, for example, to any of the important cells derived from endoderm such as lung, liver, intestine, pancreas, thymus, parathyroid and thyroid.»

Here we present a novel human Airway Lung - Chip containing a fully - differentiated human mucociliary airway epithelium separated from a pulmonary microvascular endothelium by a semi-permeable membrane that allows for immune cell infiltration.

The Swedish part of the effort, called the Human Developmental Cell Atlas (HDCA) program, includes researchers from Karolinska Institutet, Stockholm University and KTH, focusing on brain, lung, heart and fetal development during the first 12 -LSB-...]