They were created by injecting DNA derived
from human skin cells into eggs taken from cows ovaries which have had virtually all their genetic material removed.
The test procedure is performed on an in vitro skin model built at Fraunhofer IGB
from human skin cells in special culture dishes.
A human heart cell that was chemically reprogrammed
from a human skin cell.
Not exact matches
A clump of
cells with no brain, and no neural tube is no more «a
human life» than
cells from your
skin layer, or a sperm
cell with no change of fertilizing an egg.
Scientists looking for new methods to make
human tissue have successfully used cloning technology to create embryonic stem
cells from skin cells.
We referred to the news that these
cells, called induced pluripotent stem
cells (iPSCs), could be made
from human skin....
While scientists have previously had success in 3D printing a range of
human stem
cell cultures developed
from bone marrow or
skin cells, a team
from Scotland's Heriot - Watt University claims to be the first to print the more delicate, yet more flexible,
human embryonic stem
cells (hESCs).
Using a mathematical model known as the Ising model, invented to describe phase transitions in statistical physics, such as how a substance changes
from liquid to gas, the Johns Hopkins researchers calculated the probability distribution of methylation along the genome in several different
human cell types, including normal and cancerous colon, lung and liver
cells, as well as brain,
skin, blood and embryonic stem
cells.
Avivi's team has found out that fibroblast
skin cells from the armpits of the rats can kill
human cancer
cells in a dish.
This year they succeeded in generating mini-livers, or liver buds,
from stem
cells that were taken
from human skin and reprogrammed to an embryonic state.
In May 2013, Mitalipov was the first scientist in the world to demonstrate the successful use of somatic
cell nuclear transfer, or SCNT, to produce
human embryonic stem
cells from an individual's
skin cell.
A comparison of epidermal equivalents generated
from iPSC, hESC and primary
human keratinocytes (
skin cells)
from skin biopsies showed no significant difference in their structural or functional properties compared with the outermost layer of normal
human skin.
The new epidermis, grown
from human pluripotent stem
cells, offers a cost - effective alternative lab model for testing drugs and cosmetics, and could also help to develop new therapies for rare and common
skin disorders.
«
Skin layer grown
from human stem
cells could replace animals in drug, cosmetics testing.»
«The
human skin protects the body and internal
cells from environmental stresses.
Unlike the
skin cells from which they originated, the
human iPS
cells created
from FOP patients show increased cartilage formation and increased bone mineralization, two critical steps that are necessary to form mature bone.
For the purpose of additional experiments, the researchers generated myocardial
cells from embryonic stem
cells and
human skin cells, in collaboration with the lab headed by Prof Dr Jürgen Hescheler at the University of Cologne.
A California company reported today that it has, for the first time, cloned
human embryos using DNA
from adult
skin cells.
Two groups of researchers report today that washing
human skin cells in similar cocktails of four genes enabled them to reprogram the
cells to resemble those harvested
from embryos.
Now Yamanaka and his colleagues report in the journal
Cell that the same combination of genes induced pluripotency in commercially available
human fibroblasts (connective tissue
cells that play a crucial role in healing) derived
from the facial
skin of a 36 - year - old woman, the joint tissue of a man, aged 69, and a newborn, respectively.
It was found that complex II activity significantly declined with age, per unit of mitochondria, in the
cells derived
from the lower rather than the upper levels, an observation not previously reported for
human skin.
The bacterial peptide found to activate MS patients» T
cells came
from Pseudomonas aeruginosa, a common inhabitant of
human skin which can infect wounds.
The researchers are the first to grow
human vaginal
skin cells in a dish in a manner that creates surfaces that support colonization by the complex good and bad communities of bacteria collected
from women during routine gynecological exams.
Alternative
cell lines, such as induced pluripotent stem
cells generated
from patient
skin cells, offer a more accurate window on
human biology, he says.
But this process — even when taking
skin cells from an older
human — doesn't guarantee stem
cells with «older» properties.
How did you feel when you realised you had made
human embryonic - like
cells from skin cells?
One uses primary hepatocytes obtained
from livers donated for transplant; the second uses stem
cells derived
from human skin samples and guided into hepatocyte - like
cells, Bhatia says.
The researchers, led by University of California, San Diego neuroscientist Mark Tuszynski, took
skin cells from the patients, grew them up in a culture dish and genetically engineered them to make
human nerve growth factor (NGF).
The study carried out at the University of Eastern Finland used the induced pluripotent stem
cell technology, which enables the generation of pluripotent stem
cells from human skin fibroblasts.
For the new study, the team used a
cell - reprogramming technique (similar to those used to reprogram
skin cells into stem
cells) to generate
human DRG - type sensory neurons
from ordinary
skin cells called fibroblasts.
Another team,
from Stanford University, converted
human skin cells directly into neurons without first stopping at the stem
cell stage, potentially making the process more efficient.
In this new study, the scientists mimicked
human tissue formation by starting with stem
cells genetically reprogrammed
from adult
skin tissue to form small chambers with beating
human heart
cells.
A new cellular reprogramming method has been revealed that transforms
human skin cells into liver
cells that are virtually indistinguishable
from the
cells that make up native liver tissue.
Skin cells from bonobos (pigmy chimps) were reprogrammed to pluripotent stem
cells, an advance that allows scientists to study the differences between the neurons of
humans and chimps.
Writing in the latest issue of the journal Nature, researchers in the laboratories of Gladstone Senior Investigator Sheng Ding, PhD, and UCSF Associate Professor Holger Willenbring, MD, PhD, reveal a new cellular reprogramming method that transforms
human skin cells into liver
cells that are virtually indistinguishable
from the
cells that make up native liver tissue.
«It appeared we wouldn't be able to create enough
human OPCs for widespread therapeutic use, so we began to wonder if we could create them directly
from skin cells.»
«We used
human skin cells that we obtained
from patients affected with ALS and converted them into neurons via a technology called induced pluripotent stem
cell production,» she explains.
Indeed, when the researchers engineered connective tissue
cells from mouse and
human skin to produce PRDM16 and C / EBP - beta, they became fully functional brown fat.
One team in Japan, and another in the US, have independently shown it is possible to produce embryonic - like stem
cells directly
from a patient's own
skin cells without having to create and destroy a cloned
human embryo first.
Scientists at the University of Luxembourg have succeeded in turning
human stem
cells derived
from skin samples into tiny, 3 - D, brain - like cultures that behave very similarly to
cells in the
human midbrain.
The brain organoid, engineered
from adult
human skin cells, is the most complete
human brain model yet developed, said Rene Anand, professor of biological chemistry and pharmacology at Ohio State.
Xu and his team, which includes researchers
from Penn's departments of Dermatology and Biology, as well as the New Jersey Institute of Technology, started with
human skin cells called dermal fibroblasts.
Human - associated bacteria disperse into and throughout the built environment by three primary mechanisms: (1) direct human contact with indoor surfaces; (2) bioaerosol particle emission from our breath, clothes, skin and hair; and (3) resuspension of indoor dust containing previously shed human skin cells, hair and other bacteria - laden parti
Human - associated bacteria disperse into and throughout the built environment by three primary mechanisms: (1) direct
human contact with indoor surfaces; (2) bioaerosol particle emission from our breath, clothes, skin and hair; and (3) resuspension of indoor dust containing previously shed human skin cells, hair and other bacteria - laden parti
human contact with indoor surfaces; (2) bioaerosol particle emission
from our breath, clothes,
skin and hair; and (3) resuspension of indoor dust containing previously shed
human skin cells, hair and other bacteria - laden parti
human skin cells, hair and other bacteria - laden particles.
US scientists have successfully generated hypothalamic - like neurons
from human induced pluripotent stem
cells (hiPSCs) taken
from the blood and
skin cells of super-obese individuals and people with a normal body weight.
Human embryonic stem
cells derived
from affected embryos during a pre-implantation diagnostic (PGD), as well as the conversion of somatic
cells, such as
skin fibroblasts, into induced pluripotent stem
cells by genetic manipulation, offer the unique opportunity to have access to a large spectrum of disease - specific
cell models.
Gianneschi and his team found that the synthetic melanin nanoparticles in their experiments were not only absorbed and distributed normally by the keratinocytes in the epidermis, but they also protected
human skin cells from UV radiation damage.
Reykjavik, ICELAND, 25 September 2011 — Scientists at deCODE Genetics and academic collaborators
from Iceland, The Netherlands, Spain, Denmark, Germany, Sweden, the USA, the UK and Romania today report the discovery of a variant in the sequence of the
human genome associated with risk of developing basal
cell carcinoma of the
skin (BCC), as well as prostate cancer and glioma, the most serious form of brain cancer.
In this new study, the scientists mimicked
human tissue formation by starting with stem
cells genetically reprogrammed
from adult
skin tissue to small chambers with beating
human heart
cells.
The near - infrared light that causes the nanotubes to fluoresce can penetrate about eight centimeters into
human tissue, so physicians could potentially shine the light through
skin and flesh to look for fluorescence
from nanotubes signaling the presence of cancer
cells.
Two months ago, several scientists in Wisconsin and Japan announced that they had successfully created a type of stem
cell from ordinary
human skin cells that seems to be able to function exactly like an embryonic stem
cell without the need to create or destroy
human embryos.