The goal of our laboratory is to generate pluripotent stem cells
from human somatic cells.
Not exact matches
In May 2013, Mitalipov was the first scientist in the world to demonstrate the successful use of
somatic cell nuclear transfer, or SCNT, to produce
human embryonic stem
cells from an individual's skin
cell.
More recently, researchers have induced stem
cells from diseased
human somatic cells, which may serve as new model systems for various illnesses.
He reported in May 2013 using the Dolly technique, known more formally as
somatic cell nuclear transfer, to derive stem
cells from cloned
human embryos, including
from a baby with an inherited disorder.
Human embryonic stem
cells derived
from affected embryos during a pre-implantation diagnostic (PGD), as well as the conversion of
somatic cells, such as skin fibroblasts, into induced pluripotent stem
cells by genetic manipulation, offer the unique opportunity to have access to a large spectrum of disease - specific
cell models.
Human pluripotent stem
cells from two sources today, one physiological embryonic stem
cells «ES»
from the embryo, and the other experimental
cells «iPS» induced pluripotency by reprogramming genetic
somatic cells.
Disease - specific
human pluripotent stem
cells,
from embryonic origin or derived
from reprogramming
somatic cells, offer the unique opportunity to have access to a large spectrum of disease - specific
cell models.
He was also a Fulbright Scholar, and was part of the team that cloned the world's first
human embryo, as well as the first to successfully generate stem
cells from adults using
somatic -
cell nuclear transfer (therapeutic cloning).
A proprietary bioinformatics tool for the detection of aging biomarkers in DNA samples
from somatic cells of
human and mouse;
In the several years since those first reports, new advances in the derivation of hiPSCs
from various tissue sources (including those
from human patients) and using diverse reprogramming techniques, and in their use as a pluripotent
cell source in the induced differentiation of a wide array of
somatic cell types, have appeared with almost startling rapidity.
Human pluripotent stem cells derived from embryos (human Embryonic Stem Cells or hESCs) or generated by direct reprogramming of somatic cells (human Induced Pluripotent Stem Cells or hiPSCs) can proliferate almost indefinitely in vitro while maintaining the capacity to differentiate into a broad diversity of cell t
Human pluripotent stem
cells derived from embryos (human Embryonic Stem Cells or hESCs) or generated by direct reprogramming of somatic cells (human Induced Pluripotent Stem Cells or hiPSCs) can proliferate almost indefinitely in vitro while maintaining the capacity to differentiate into a broad diversity of cell t
cells derived
from embryos (
human Embryonic Stem Cells or hESCs) or generated by direct reprogramming of somatic cells (human Induced Pluripotent Stem Cells or hiPSCs) can proliferate almost indefinitely in vitro while maintaining the capacity to differentiate into a broad diversity of cell t
human Embryonic Stem
Cells or hESCs) or generated by direct reprogramming of somatic cells (human Induced Pluripotent Stem Cells or hiPSCs) can proliferate almost indefinitely in vitro while maintaining the capacity to differentiate into a broad diversity of cell t
Cells or hESCs) or generated by direct reprogramming of
somatic cells (human Induced Pluripotent Stem Cells or hiPSCs) can proliferate almost indefinitely in vitro while maintaining the capacity to differentiate into a broad diversity of cell t
cells (
human Induced Pluripotent Stem Cells or hiPSCs) can proliferate almost indefinitely in vitro while maintaining the capacity to differentiate into a broad diversity of cell t
human Induced Pluripotent Stem
Cells or hiPSCs) can proliferate almost indefinitely in vitro while maintaining the capacity to differentiate into a broad diversity of cell t
Cells or hiPSCs) can proliferate almost indefinitely in vitro while maintaining the capacity to differentiate into a broad diversity of
cell types.