Not exact matches
An example comes
from a patient with familial
hypercholesterolemia — a disease that causes high blood levels of «bad» LDL (low - density lipoprotein) cholesterol because a cellular defect prevents the liver
from absorbing LDL.
Reported today in Disease Models & Mechanisms, Karim Si - Tayeb and colleagues in the research group of Bertrand Cariou
from l'Institut du Thorax, Nantes used an innovative approach to develop unique patient cell - based models of PCSK9 - driven
hypercholesterolemia.
However, there are rare occurrences where high blood levels of LDL cholesterol result
from a genetic defect called familial
hypercholesterolemia (FH).
Hypercholesterolemia - prone mice that were engrafted with bone marrow obtained
from homozygous or heterozygous Tet2 knockout mice had larger atherosclerotic lesions in the aortic root and aorta than did mice that had received control bone marrow.
A study
from an international research team finds that familial
hypercholesterolemia — a genetic condition that causes greatly elevated levels of LDL cholesterol throughout life — accounts for less than 2 percent of severely elevated LDL in the general population but also increases the risk of coronary artery disease significantly more than does elevated LDL alone.
Management of familial
hypercholesterolemia: a review of the recommendations
from the national lipid association expert panel on familial
hypercholesterolemia.
The most effective diets ever used to cure people of common day illnesses, like coronary heart disease, type - 2 diabetes, hypertension,
hypercholesterolemia, arthritis, and obesity minimize animal foods and require people eat the bulk of their calories
from starches, including grains, legumes, and potatoes (foods forbidden to Paleo eaters).
1) A genetic Condition called Familial
Hypercholesterolemia which affects 1 in 500 people, where a person's liver expresses much less LDL receptors and is therefore unable to clear «used» cholesterol in LDL particles
from the blood
Many doctors believe that most patients with familial
hypercholesterolemia (FH) die
from CHD at a young age.
(3) 75 % of dogs suffering
from elevated cholesterol are hypothyroid dogs, a condition called
hypercholesterolemia.