Sites are organized by distance
from known genes: extreme, > 100 kb; distal, between 10 — 100 kb; proximal, between 0 — 10 kb; intronic and exonic, within known genes.
Not exact matches
DNA - testing companies determine where your
genes are
from by comparing you to other users who are
known to have ancestors
from that region.
At last year's Brainstorm Health conference in San Diego, Bergh found himself sitting at dinner with Othman Laraki, the cofounder and CEO of Color Genomics — a company that extracts the DNA
from a customer's submitted saliva sample and then looks for a set number of
gene mutations
known to be associated with increased risk for developing certain hereditary cancers or heart conditions (depending on the test).
By invalidating key parts of Myriad's patents, the court has removed a bar that prevented labs using new technology
from developing and selling broader one - time tests that search for all
known cancer risks, including the BRCA
genes, geneticists said.
People of every nation, color, language, belief, and condition are now
known to possess in their body cells trait factors drawn by an inconceivably complex sequence of intercombinations
from a common «
gene pool.»
Last, had I
known that alcoholism is a disease worse than cancer, and that it ran through the family
genes thus any baby born had a strong chance of becoming one... well, that seals the deal but, I bet the parents who also fell for religiosity, not
knowing it was an enclave for pedophiles... talk about regrets
from hell.
In addition, there are people who
know their lineage
from Moses» time — in fact, it is in their
genes.
The most powerful influence in human life is neither the environment in which we happen to be brought up, the
genes we were bequeathed
from our parents at birth, nor all the slings and arrows of fate,
no matter how tragic and harrowing their effects may be.
They are
no more alike than any sibling set, sharing about 50 % of their genetic markers in a unique combination of
genes from both parents.
We don't
know much about phallus evolution (external genitalia generally don't mineralize, so the fossil record is of little help), but we can compare the expression of phallus
genes from organism to organism.
Join Josh and Chuck as they explore the science behind the Stuff You Should
Know about everything
from genes to the Galapagos.
After Lin's team first published the link between the ATF6
gene and this type of inherited vision loss,
known as achromatopsia or cone - rod dystrophy, a few years ago, people with these conditions began contacting them
from around the world.
It is well
known that
genes are passed
from one generation to the next.
Known in Catalan as Floquet de Neu, Snowflake became a famous resident of the Barcelona Zoo in Spain because of his unique skin color, the result of a rare albinism
gene inherited
from both parents.
The authors examined DNA samples
from 62 people who died
from SUDEP, searching for mutations in
genes known to contribute to cardiac arrhythmia, respiratory function and epilepsy.
As microbiologists have pointed out, bacteria are
known to scavenge
genes from the spilled DNA of their dead.
Last April, they announced that they had raised the total number of
known genes from 4 million to 10 million.
PONDERING whether a baby got mum or dad's eyes may seem like idle speculation, but
knowing which parent certain
genes came
from can tell you about your risk of disease.
Cannibals — whether microbes or Methodists — who eat their own relatives can also experience decreases in a measure of evolutionary success
known as inclusive fitness, in which the survival of an individual's
genes, whether they're
from an offspring or a collateral relative (like a brother or cousin) is the true measure of evolutionary success.
A mutant in the corresponding
gene from arabidopsis is already
known, but here it was only
known that — as the mutant name Snowy Cotyledon indicates — it results in white cotyledons (the first two leaves).
The function of the EST — or at least the function of the
genes from which they are derived — is therefore
known.
What most people
know about the inheritance of eye color is that brown comes
from a dominant
gene (needing one copy only) and blue
from a recessive
gene (needing two copies).
However, the positive impacts of biochar were coupled with negative findings for a suite of
genes that are
known to determine the ability of a plant to withstand attack
from pests and pathogens.
Who
knows, those lost
genes might be useful to us 1,000 years
from now, but there's no way to preserve them.
«With more than 100
genes already
known to cause deafness in humans, there are many patients who may eventually benefit
from this technology.»
«Professor Hummon and I have been mapping
gene expressions for the right versus the left side of the colon, which we now
know are different
from each other due to the way the colon forms,» said Buechler.
One way to get many types of cells or proteins
from the same genetic starting material is by mixing and matching different parts of one
gene to produce multiple
gene readouts, a phenomenon
known as alternative splicing.
«
From other studies ***** we
know that epigenetic modifications of the DPP4
gene, which are associated with an increased production of the enzyme, have a negative impact on the liver metabolism already in young mice, long before fatty liver disease emerges,» says Baumeier.
To find out whether they had evolved to cope, Andres Moreno at Stanford University in California and colleagues looked at the variation of a
gene known to be involved in water retention in the kidney, called FOXI1, in DNA samples
from 20 Europeans, 20 east Asians and 20 Yoruba.
In fact, the FDA has ruled that because DNA is in every living organism, crops engineered with added
genes are «substantially the same» as other foods and are
no different
from crops genetically modified through conventional breeding techniques.
A concerning finding among the Brazilian hybrids was that one was 51 per cent earworm but included a
known resistance
gene from the bollworm.
Surprisingly, the cancer - promoting program that RB - loss unleashed was distinct
from the cell - cycle control
genes that RB is best
known for controlling.
Probably, the
genes we
know from other animals have a different function in sponges and were co-opted later for the function we are familiar with.»
No one
knows where or when this happened, but plant pathologists discovered last year that yellow rust can reproduce sexually, suggesting the new strain may have picked up
genes from local strains by mating with them.
The two
genes implicated — GNAQ and GNA11 — code for proteins (
known as G proteins) that normally function as molecular on - off switches, regulating the passage of information
from the outside to the inside of a cell.
Dwarki and Jaime Escobedo improved the AAV's ability to insert
genes into chromosomes by adding a
gene promoter region
from cytomegalovirus,
known to be active in the target for their
gene therapy, muscle cells.
Furthermore,
genes are reliably passed
from one generation to another: Schrödinger explained to his audience that a well -
known characteristic such as the Hapsburg, or Habsburg, lip — the protruding lower jaw shown by members of the House of Hapsburg — can be tracked over hundreds of years, without apparently changing.
«We don't
know what's going on in Indonesia,» says Andrea Gambotto, a University of Pittsburgh vaccinologist who has also developed an innovative vaccine based on H5N1
genes from Vietnam.
The researchers used «bait» proteins
from over two dozen
known autism
genes, fishing in a pool of human DNA for other proteins that would interact with the baits.
The group has already started tweaking human iPS cells using the same
genes that Saitou pinpointed as being important in mouse germ - cell development, but both Saitou and Hayashi
know that human signalling networks are different
from those in mice.
«Little is
known even about what
genes distinguish one neuron
from another, even though they might perform quite different functions,» Kandel says.
Next, together with scientists
from the Transfaculty Research Platform, they investigated whether any
known schizophrenia risk
genes are associated with the hippocampus.
«Invasive weed Kochia's resistance to well -
known herbicide stems
from increase in
gene copies.»
Here, segments of RNA
known as transcripts — derived
from specific DNA
genes — hold vital clues regarding health.
They
knew that they had found a new type of genetic defect, because the DNA in cancer cells
from people with the altered
gene was riddled with mutations.
But those
from the hotter pool survived for longer and had higher expression of 60
genes, including well -
known thermal - tolerance
genes such as those that make heat - shock proteins and antioxidant enzymes.
The Nature study also adds to what is
known about how
genes are transferred
from one species to another when individuals
from two closely related species mate.
Martens suggests that the discovery of a new type of
gene in largely ignored nether regions of DNA means that the secrets of the genome are far
from known.
«Many research groups are looking at how
genes are regulated
from the perspective of which
genes need to be turned «on» for a cell to advance to the next stage of development, but now we see that it's just as important to
know which
genes need to be turned «off,»» Cook - Andersen said.
Using a
gene from fruit flies, scientists have produced the most resilient and stretchy rubber
known.