Sentences with phrase «from lab mice»

In a petri dish, Rowe and colleagues could tell that the bark scorpion venom works by targeting Nav1.7 in cells from lab mice and grasshopper mice.

To test the theory, he and his colleagues analyzed bacteria in fecal samples from lab mice kept in normal 12 - hour cycles of light and darkness.

Not exact matches

Most of its fellows collaborate with universities that generate fresh data from «wet» labs — the ones with autoclaves and genetically engineered mice — and other facilities.

In 2010, researchers from the University of Michigan Comprehensive Cancer Center published a study in the journal Clinical Cancer Research showing that sulforaphane had the ability to kill breast cancer stem cells in mice and in lab cultures, and it also prevented the growth of new tumor cells.

The Salk team therefore took human brain organoids that had been growing in lab dishes for 31 to 50 days and implanted them into mouse brains (more than 200 so far) from which they had removed a tiny bit of tissue to make room.

In the new work, published June 10 in the journal Scientific Reports, Zhao, Reid and colleagues used a highly sensitive probe to measure electrical fields in the corneas of isolated eyes from three different lab mouse models with different types of diabetes: genetic, drug - induced and in mice fed a high - fat diet.

«They have the genetics of lab mice, but they also have a microbiome from the outside world that promotes fitness.»

Chesser says some of his group's studies of mice exposed to radioactivity around Chernobyl hint at hormesis: Small exposures over 10 to 45 days, they found, appeared to temper damage from an acute radiation dose delivered in the lab later.

The researchers then transplanted the gut bacteria from healthy, wild Maryland mice (which were most similar genetically to the lab mice) into the lab mice.

Researchers aware of this reality have now shown that transplanting gut bacteria from wild mice into «clean» lab mice has made those rodents less likely to die from the flu or develop cancer.

Concerned that the immune systems of clean mice might not be good proxies for the human immune system — no human is brought up in such clean conditions and fed such clean food — they housed lab mice with mice from a pet store.

The gut bacteria from the wild mice were fairly similar, but the microbiomes of the lab mice were significantly different, with fewer Bacteroidetes and Proteobacteria, for example.

Now, immunologists at the National Institute of Diabetes and Digestive and Kidney Diseases in Bethesda, Maryland, have contaminated lab mice in a different way: by giving them gut bacteria from wild mice.

Barbara Rehermann and Stephan Rosshart first collected 800 wild house mice (Mus musculus domesticus) in the Washington, D.C., metro area, and compared their DNA and gut bacteria both with a lab mouse strain and with wild mice from all over the world.

The study's lead author, Toni - Lee Sterley, a postdoctoral associate in Bains» lab said, «What was remarkable was that CRH neurons from the partners, who were not themselves exposed to an actual stress, showed changes that were identical to those we measured in the stressed mice.»

With collaborators from India, Japan, and the United States, the inStem lab is exploring «biochemistry, biophysics, humanized mouse models, and single - cell models.»

The study also includes three co-first authors: Qingjian Han from Ji's group who discovered SHANK3 in sensory neurons and pain defects in SHANK3 mutant mice; Yong Ho Kim, an electrophysiologist in Ji's group who found diminished TRPV1 function in SHANK3 mutant mice; and Xiaoming Wang from Jiang's lab who generated SHANK3 mutant mice.

Pregnant female lab mice received the brew in their drinking water at four concentrations, from 400 parts per million (ppm) down to less than 0.04 ppm — equivalent to one drop of pesticide in 500 bathtubs of water, Porter says.

Instead of mice, it produces fluorescent zebrafish, which are easier for the undergraduate - staffed lab to handle, in part because they go from fertilization to free - swimming fish in a matter of days.

Transplants grown from stem cells in the lab can help replenish the blood and have been used to cure anaemia in mice.

The ban is particularly problematic for researchers who need transgenic mice, which are often ordered from specialized labs.

Every two weeks, scientists come from universities in the United States and abroad to spend a week at the D - lab learning the secrets of optogenetics, mastering everything from mouse surgery to cooking up viruses.

When Kyoto University researcher Shinya Yamanaka announced in 2006 that his lab had created iPS cells from mouse skin cells for the first time, biologists were stunned.

Egg and sperm - like cells have recently been derived from animal stem cells, and this year the first mice were born from lab - grown sperm.

Related sites Hiroshi Hamada's site Mouse Embryo Development movie from University of New South Wales Left - Right Asymmetry research in Mark Mercola's Lab

Now, a preclinical study, from the lab of Olivier Berton, PhD, an assistant professor in the department of Psychiatry, in collaboration with Sheryl Beck, PhD, a professor in the department of Anesthesiology at Children's Hospital of Philadelphia, found that bullying and other social stresses triggered symptoms of depression in mice by activating GABA neurons, in a never - before - seen direct relationship between social stimuli and this neural circuitry.

A 2013 paper from her lab published in the journal Molecular and Cellular Neuroscience showed that MHCI is even present in the fetal - mouse brain, at a stage when the immune system is not yet mature.

To investigate the relationship between temperature and immune response, Iwasaki and an interdisciplinary team of Yale researchers spearheaded by Ellen Foxman, a postdoctoral fellow in Iwasaki's lab, examined the cells taken from the airways of mice.

More recently, Wagers's lab, together with cardiologist Richard Lee's lab at Brigham and Women's Hospital in Boston, isolated a specific protein from mouse blood that they think can explain some of the effects.

Back in the lab, the ecologists counted up the attacks by different predators — they can tell the nick of a bird's beak from the teeth marks of a mouse or the paired piercings of ant, for example.

Because the amount of fibrosis in the liver is associated with a greater risk of death from NASH, Xiaobo Wang, PhD, associate research scientist in the Department of Medicine at CUMC working in the lab of Ira Tabas, MD, PhD, looked for ways to stop fibrosis in a mouse model of NASH.

One example comes from the lab of Sheryl Moy, professor of psychiatry and director of the mouse behavioral phenotyping core at the University of North Carolina's Carolina Institute for Developmental Disabilities.

These findings were confirmed by two - photon imaging of neurons in the brains of living mice by the lab of collaborator Yi Zuo, PhD, a neuroscientist at UC Santa Cruz, as well as electrophysiological recordings from neurons in brain slices by the lab of collaborator Vikaas Sohal, MD, PhD, an associate professor of psychiatry at UCSF.

Mitchell, a biomedical informaticist, and first author Colin Huber statistically analyzed data gleaned from 51 existing lab studies in mice genetically augmented with a human form of Alzheimer's.

As expected, biochemical experiments in the Cheyette lab revealed that DIXDC1 mutations impaired WNT signaling in neurons from affected mice.

As controls, fibroblasts and secretions from normal lab rats, mice, and another rodent called the spiny mouse were powerless to stop the human cancer cells growing.

Prather's lab has previously engineered E. coli to produce glucaric acid by adding three genes — one each from yeast, mice, and a strain of bacteria called Pseudomonas syringae.

Unable to make his case in studies with lab mice (because H. pylori affects only primates) and prohibited from experimenting on people, Marshall grew desperate.

In an extensive sleuthing expedition that looked back nearly 20 years, two collaborating research teams contend that they have evidence that xenotropic murine leukemia virus — related virus (XMRV) resulted from the chance recombination of pieces of two mouse viruses in lab experiments and that the connections to human disease are spurious.

Ward's lab team took skin tissue samples from her well - established psoriasis transgenic mouse model, called the KC - Tie2 mouse, and compared it to skin tissue samples of normal mice.

To test his idea, he sucked fat cells from the skin of lab mice.

VANCOUVER, CANADA — The life of the lab mouse is a far cry from the world of a hungry child in Africa.

To find out if this was true, workers in stem - cell biologist Irving Weissman's lab at Stanford University Medical School took one blood stem cell from an adult mouse and tagged it with a marker that glowed green under fluorescent light.

For the first time, researchers have been able to grow, in a lab, both normal and primary cancerous prostate cells from a patient, and then implant a million of the cancer cells into a mouse to track how the tumor progresses.

Sitting in her airy Jackson Lab office, accessible to germy and perturbing strangers, Chesler clicks open a series of photographs from a type of mouse personality test on her computer screen.

Led by Rowitch lab postdoctoral fellow Anna Molofsky, MD, PhD, the researchers studied the spinal cord sensory motor circuit, which allows both mice and humans to react without thought — to jerk a limb away from something hot, for instance.

«Here we demonstrate that even mice who fully recover from the H1N1 influenza virus responsible for the previous pandemic (also called «swine flu») are later more susceptible to chemical toxins known to trigger Parkinson's in the lab.»

Lab mice get a much lower part of their calories from carbohydrates than humans do, she points out.

Last year, as a first step in defining a «normal» lab mouse microbiome, they analyzed feces from mice from two major vendors.

Earlier this year, his lab brought in its own «dirty» colony from a company that sells mice as food for zoo animals.