Sentences with phrase «from laboratory models»

Not exact matches

Amandine Aftalion from the Mathematics Laboratory in Versailles (CNRS / University of Versailles - Saint - Quentin - en - Yvelines) and Frédéric Bonnans from the Center of Applied Mathematics (CNRS / Inria / École polytechnique) have produced a mathematical model to optimize running, which could lead to personal e-coaching customized to each individual's physiological state.

Like its European model, SESAME was conceived in part to motivate the region's best and brightest to stay, or even to return from abroad; the laboratory should also create excitement and opportunity that will attract young students to science.

Currently, Deng's laboratory is conducting additional preclinical studies using the human - derived stem cells from Down syndrome patients and mouse models to determine whether cellular and behavioral abnormalities can be improved with minocycline therapy and other candidate drugs.

As it matures, the authors wrote, it is moving «from laboratory - based experimental studies in model systems to a mature discipline that is yielding products that are being evaluated and used in the clinical domain.

We are cautiously optimistic, appreciating that the transition from laboratory animal models to the clinical setting is often challenging,» commented Dr. Davis.

«The problem is that most of the plant - tolerance models we currently use to predict these outcomes are based on laboratory studies or plant physiological studies, so they often don't factor in the compounding effects of simultaneous stressors like drought and pressure from natural enemies.

In fact, air concentrations of carbon dioxide have to build up to more than 10 percent to be hazardous, which is difficult to achieve, according to modeling from Lawrence Livermore National Laboratory (LLNL).

The survey coincides with a shift in ecology away from teaching and research rooted in natural history and toward modeling, laboratory and theoretical research, which tend to attract more grant funding and publications in higher - impact academic journals.

Working at the Linac Coherent Light Source (LCLS) X-ray laser at the Department of Energy's (DOE's) SLAC National Accelerator Laboratory, the scientists then used a newly designed injection system, engineered by a team from Arizona State University, to stream the gel into the path of the X-ray pulses, which hit the crystals and produced patterns used to reconstruct a high - resolution, 3 - D model of the receptor.

In the study, Lauren Lowman, a doctoral student in Barros's laboratory, used a hydrological computer model to simulate the ecological impacts of tropical cyclones from 2004 - 2007.

«We are beginning to see that melanocytes integrate signals from several receptors to modulate pigment production, which will help us build a more complete model of how pigmentation is regulated,» said Christopher A. Natale, a graduate student in the Ridky Laboratory, and first author of the study.

In her 4 years at Furman University in Greenville, South Carolina, Laura Glish, a 2006 graduate, worked on collaborative projects in two different laboratories and explored a variety of experimental techniques, from atomic force microscopy to synthetic chemistry and molecular modeling.

A study combining tumor cells from patients with breast cancer with a laboratory model of blood vessel lining provides the most compelling evidence so far that a specific trio of cells is required for the spread of breast cancer.

Thanks to the development of a simulation model for the breathing process of a person in a dusty work environment, researchers from the J.M Madariaga Official Laboratory (LOM) and Universidad Politécnica de Madrid (UPM) have designed a method capable to experimentally determine the efficacy of a series of existing filters and masks in the market.

A team led by Charles R. Carrigan at Lawrence Livermore National Laboratory (LLNL) used field experiments to build a new, complex model that predicts isotopic ratios of noble gases that would be released from such explosions (Sci.

«These beautiful measurements from the South Pole Telescope and Herschel strengthen our confidence in our current model of the universe,» said Olivier Doré, a member of the U.S. Planck science team at NASA's Jet Propulsion Laboratory, Pasadena, Calif. «However, this model does not tell us how big the primordial signal itself should be.

A team of researchers from the Hyperbaric Biomedical Research Laboratory at the University of South Florida (USF) doubled survival time in an aggressive metastatic cancer model using a novel combination of non-toxic dietary and hyperbaric oxygen therapies.

Apart from a few studies in mouse models and in cell lines, there is no laboratory evidence that synthetic phosphoethanolamine works as a cancer drug.

The researchers developed algorithms to use in a «systems biology modeling cycle,» in which they repeatedly fit a model to gene expression data obtained from laboratory experiments until a good fit was obtained between the predicted and the measured outcomes.

The scientists are able to use tissue not only from laboratory mouse models, but also from human patients.

For assessing the global ocean - carbon sink, McKinley and her co-authors from the National Oceanic and Atmospheric Administration (NOAA) Pacific Marine Environmental Laboratory, NCAR and the University of Colorado Boulder used the model to establish a long - running climate scenario from historical data.

Using large - scale numerical modeling as well as GPS velocities from the largest GPS data - processing center in the world — the Nevada Geodetic Laboratory at the University of Nevada, Reno — Kreemer and Gordon have showed that cooling of the lithosphere, the outermost layer of Earth, makes some sections of the Pacific plate contract horizontally at faster rates than other sections.

The contribution from dust «appears to be somewhat higher than the pre-Planck models predicted,» says BICEP2 team member Jamie Bock of the California Institute of Technology and NASA's Jet Propulsion Laboratory, both based in Pasadena.

In their research, scientists at Rutgers created animal models that closely resemble the cancerous tumors found in women with ovarian cancer by injecting tumor tissues obtained from gynecological cancer patients treated at the Cancer Institute into laboratory mice.

Shown are the 1988 - 2014trends in springtime ozone levels on days that were very smoggy (top panel) and of average smogginess (bottom panel), from observations (left) and from a model built by the Geophysical Fluid Dynamics Laboratory (right).

Now, after more than a decade, Prusiner and researchers at other laboratories have produced a simple model of how prions from a diseased brain could replicate.

The participants were M.I.T.'s Alan Guth, the developer of the inflationary model of the universe, Lawrence Krauss, a frequent contributor to Scientific American magazine and director of the Origins Initiative at Arizona State University, John Carlstrom from the University of Chicago, who studies the cosmic microwave background radiation left over from the big bang and Scott Dodelson of the Fermi National Accelerator Laboratory, who studies the origin and structure of the universe.

LUX improvements, coupled to advanced computer simulations at the U.S. Department of Energy's Lawrence Berkeley National Laboratory's (Berkeley Lab) National Energy Research Scientific Computing Center (NERSC) and Brown University's Center for Computation and Visualization (CCV), have allowed scientists to test additional particle models of dark matter that now can be excluded from the search.

«For example, there is a huge amount of interest and excitement globally in growing cerebral organoids» — miniature brain - like organs that can be studied in laboratory experiments — «from stem cells to model human brain development and disease mechanisms.

As DOE laboratories have gradually hired talented staff away from NCAR, another concern was that a new model would vacuum up valuable expertise that otherwise was needed for model development.

«Eliminating endothelial CD146 by conditional knockout in two different mouse models of colitis significantly reduced the severity of inflammation and decreased tumor incidence and tumor progression in a mouse model of CAC,» reports lead investigator Xiyun Yan, PhD, from the Key Laboratory of Protein and Peptide Pharmaceuticals, Institute of Biophysics, Chinese Academy of Sciences, Beijing.

«This is an excellent example where hypotheses developed over the years from laboratory experiments and theoretical models could be tested and verified in nature,» said co-author Seewald.

A study published April 7 in PNAS Online Early Edition describes how a team of scientists, including researchers from the University of California, Davis, showed that vapor losses to the walls of laboratory chambers can suppress the formation of secondary organic aerosol, which in turn has contributed to the underprediction of SOA in climate and air quality models.

Several laboratories, including one led by Stewart Anderson of the University of Pennsylvania Perelman School of Medicine, have demonstrated that transplanting inhibitory neurons from healthy mice has improved symptoms in mice with models of those diseases.

Along with scientists and engineers from Lawrence Livermore National Laboratory and Sandia National Laboratories, the Berkeley Lab crew made up the so - called «Lab Team,» called in by state officials for their expertise in well integrity and well - flow modeling.

Using statistical models, a team of researchers from the British Antarctic Survey and Plymouth Marine Laboratory assessed the likely impact of projected temperature increases on the Weddell Sea, Scotia Sea and Southern Drake Passage, which is known for its abundance of krill.

Researchers at MIT's Computer Science and Artificial Intelligence Laboratory have developed a new computational model of a neural circuit in the brain, which could shed light on the biological role of inhibitory neurons — neurons that keep other neurons from firing.

Using large - scale numerical modeling as well as GPS velocities from the largest GPS data - processing center in the world - the Nevada Geodetic Laboratory at the University of Nevada, Reno - Kreemer and Gordon have showed that cooling of the lithosphere, the outermost layer of Earth, makes some sections of the Pacific plate contract horizontally at faster rates than other sections.

The article, which is authored by an interdisciplinary group of scientists from the fields of economics and banking, ecology, epidemiology, physics, computer science and sociology argues that applications of complex networks, agent - based models and laboratory experiments offer great potential to better grasp complex financial economic systems.

Bar Harbor, Maine — October 21, 2004 — The Jackson Laboratory is pleased to announce that it has received support from the Spinal Muscular Atrophy Foundation to make available the first group of mouse models for spinal muscular atrophy (SMA), a neuromuscular disease and the leading genetic cause of death among infants and toddlers.

The Earth, Venus, Archean Earth, and super-Earth models are from the Virtual Planet Laboratory.

And there are a lot of treatments, or let's say potential treatments, that are working wonderfully in preclinical models that are ready to make the leap to human testing, and some of these have begun to make that transition to bridge from the laboratory to human - patient testing.

«But the timing was optimal; when the new DNA sequencing machines were unpacked at our newly established laboratory, DNA arrived from our model spruce tree.

Results: Researchers at Pacific Northwest National Laboratory — in collaboration with NERSC, Argonne National Laboratory, and Cray — recently achieved an effective aggregate IO bandwidth of 5 Gigabytes / sec for writing output from a global atmospheric model to shared files on DOE's «Franklin,» a 39,000 - processor Cray XT4 supercomputer located at NERSC.

Previous recipients of the prize include the godfather of climate modelling, Syukuro Manabe, from the US National Oceanic and Atmospheric Administration's Geophysical Fluid Dynamics Laboratory, Norway's former Prime Minister Gro Harlem Brundtland, and Charles Keeling from the University of California at San Diego who gave his name to the famous Keeling curve of atmospheric CO2 concentration measurements.

Using this information, they implemented formulas (parameterizations) describing the information gained from the laboratory ice nucleation measurements and implemented this into the global model.

While the Huhman laboratory primarily uses inescapable social defeat to model the clinical psychopathologies (e.g., anxiety, posttraumatic stress disorder) that can result from bullying or abuse, researchers have also shown that exposure to escapable social defeat results in CD, albeit to a reduced degree.

In a defining document about the future of aerosol research, Pacific Northwest National Laboratory scientist Steve Ghan teamed with Brookhaven National Laboratory's Steve Schwartz, Chief Scientist for the Department of Energy's Atmospheric Science Program, to describe a disciplined process for successfully moving aerosol research from the observational stage to model simulations.

Establishing a repository of laboratory models derived from patient tumor samples that will enable researchers to more thoroughly investigate drug resistance

Reference: Ghan, S.J., and S.E. Schwartz, 2007: Aerosol Properties and Processes: A Path from Field and Laboratory Measurements to Global Climate Models.