Sentences with phrase «from large cohort studies»

For this population - based research, investigators pooled data from large cohort studies conducted in Asia and included demographic and risk factor information collected in seven Asian regions from the early 1960s through the late 1990s (although most of the studies enrolled participants after the mid-1980s).

Major depressive disorder and hypothalamic — pituitary — adrenal axis activity: Results from a large cohort study

Not exact matches

«For this large cohort of women who planned midwife - led home births in the United States, outcomes are congruent with the best available data from population - based, observational studies that evaluated outcomes by intended place of birth and perinatal risk factors.

Commenting on the study, ESMO spokesperson Dirk Arnold, MD, PhD, from Instituto CUF de Oncologia in Lisbon, Portugal, said «this large population - based cohort - control study impressively confirms the hypothesis of an association of colorectal polyps with diets and other life - style factors.

The most influential evidence came from large prospective cohort studies conducted over the past 20 years.

To identify the relevant mutations the scientists analyzed the blood samples of 1,858 men from three independent cohorts in Europe and North America: the Swiss arm of the European Randomized Study for Prostate Cancer Screening, the large American Screening trial, Prostate, Lung, Colorectal, and Ovarian (PLCO), Princess Margaret Cancer Centre (University Health Network) and Mount Sinai Hospital (Sinai Health System) in Toronto.

The Chronic Hepatitis Cohort Study is an analysis of records from a large, geographically and racially diverse group of 9,783 patients receiving care at four large U.S. health systems: Henry Ford Health System in Detroit; Kaiser Permanente Northwest in Portland, Oregon; Kaiser Permanente in Honolulu and Geisinger Health System in Danville, Pennsylvania.

Findings from this UK cohort are confirmed by evidence for adult - onset ADHD world - wide: a study from Brazil will be published by JAMA Psychiatry alongside this research, which also identified a large proportion of adults with ADHD as not having the disorder in childhood.

Young adults with thinner cortex in particular brain regions are more impulsive during a decision - making task than teens with thicker cortex, according to a large correlational study of adolescents from the Philadelphia Neurodevelopmental Cohort.

The researchers analysed data from a large Norwegian population - based pregnancy cohort study called MoBa, which involves a range of data collected from mothers and children during and after pregnancy.

From this survey data, NASA's James Webb Space Telescope as well as large ground - based observatories will be able to further characterize the targets, making it possible for the first time to study the masses, sizes, densities, orbits, and atmospheres of a large cohort of small planets, including a sample of rocky worlds in the habitable zones of their host stars.

Dr. Zhang points out that the unique value of this study derives from the ability to perform longitudinal assessments of cognition in PD patients over a long time period and access to data from a large cohort that began when patients were in the earliest stage of disease.

Dr Matt Hurles, who led the study from the Sanger Institute, said: «This study has the largest cohort of such families in the world, and harnesses the power of the NHS, with 200 clinical geneticists and 4,000 patients.

The prospective study included 23,928 participants without coronary heart disease from Reasons for Geographic and Racial Differences in Stroke (REGARDS), a large biracial population - based cohort study.

Researchers were able to access CSF samples from the deprenyl and tocopherol antioxidative therapy of Parkinsonism (DATATOP) study, which is the largest cohort assembled to date with longitudinal collection of biological fluids and clinical data from PD patients.

Nechuta and colleagues used data from the Shanghai Women's Health Study, a large, population - based prospective cohort study of about 75,000 women ages 40 to 70, from Shanghai, China, led by Wei Zheng, MD, PhD, at the Vanderbilt Epidemiology CeStudy, a large, population - based prospective cohort study of about 75,000 women ages 40 to 70, from Shanghai, China, led by Wei Zheng, MD, PhD, at the Vanderbilt Epidemiology Cestudy of about 75,000 women ages 40 to 70, from Shanghai, China, led by Wei Zheng, MD, PhD, at the Vanderbilt Epidemiology Center.

The study comprised data from three large cohorts, where individuals were subjected to repeated lung function measurements over the course of many years.

The Columbia researchers with colleagues in Finland conducted an analysis of data from the Finnish Prenatal Study of Schizophrenia, a large, national birth cohort with an extensive bio-bank.

Of the dozen of these metabolites that were measured in cohorts from the longitudinal Framingham Heart Study (the long - term 1948 study to identify the common contributive factors of cardiovascular disease by following its development in a large subject group) levels of glycerol turned out to be «significantly correlated» with resting heart rate, another indicator of fitness, as measured in the sStudy (the long - term 1948 study to identify the common contributive factors of cardiovascular disease by following its development in a large subject group) levels of glycerol turned out to be «significantly correlated» with resting heart rate, another indicator of fitness, as measured in the sstudy to identify the common contributive factors of cardiovascular disease by following its development in a large subject group) levels of glycerol turned out to be «significantly correlated» with resting heart rate, another indicator of fitness, as measured in the studystudy.

Researchers analyzed data from a large national birth cohort of pregnant women who participated in the Finnish Prenatal Study of Schizophrenia and their offspring from the Finnish Maternity Cohort, which archived over 1 million prenatal serum specimens sincecohort of pregnant women who participated in the Finnish Prenatal Study of Schizophrenia and their offspring from the Finnish Maternity Cohort, which archived over 1 million prenatal serum specimens sinceCohort, which archived over 1 million prenatal serum specimens since 1983.

Investigators looked at data from a large, nationally representative sample of preschool - aged children — the Early Childhood Longitudinal Study - Birth Cohort, conducted by the National Center for Education Statistics.

In this study, researchers used blood samples collected several years before breast cancer development from two large UK cohorts of women — the MRC National Survey of Health and Development and the UK Collaborative Trial of Ovarian Cancer Screening.

«Metabolomics is now often used to accompany large genomic cohort studies from biobanks, to correlate genotype and genomic variants with specific phenotypes, to complement nutritional studies monitoring food components or endogenous metabolites, or to support measurements in epidemiology studies,» says Andreas Huhmer, director of proteomics and metabolomics marketing at Thermo Fisher Scientific, headquartered in Waltham, Massachusetts.

The NYGC and its founding member institutions are conducting additional studies involving Watson to help accelerate the discovery of potentially actionable sequence variants in various types of cancer, including an ongoing study that involves DNA and RNA from a larger cohort of glioblastoma patients, and a study of 200 patients with different types of cancer.

«We're looking forward to longer - term results to come in the next five years from various ongoing observational studies,» Dr. Arterburn said: The Utah Obesity Study, the Michigan Bariatric Surgery Collaborative, and large cohorts from Veterans Affairs health system and the HMO Research Network (including Group Health) and should yield important long - term information comparing the efficacy, safety, and costs of surgical and non-surgical care for severe obesity.

Samples from large, well - phenotyped cohorts have always been in high demand for genetic studies.

Conclusions and Relevance The study results, derived from a large cohort of patients with long follow - up time, suggest that the rate of revision septorhinoplasty is low, but certain patient characteristics are associated with higher revision rates.

The study results, derived from a large cohort of patients with long follow - up time, suggest that the rate of revision septorhinoplasty is low, but certain patient characteristics are associated with higher revision rates.

Dr. Polonis» lab has focused for many years on functional antibodies elicited by natural infection and by vaccination, utilizing samples from multiple natural history cohorts and vaccine studies; her lab is currently performing an extensive analysis of pseudovirus neutralizing antibodies in the large RV144 follow - on trial, RV306.

«We will be able to link all of our group's discoveries using blood samples and clinical data from the extensive NHLBI - sponsored Multi-Ethnic Study of Atherosclerosis (MESA) cohort, a large longitudinal cohort established in 2000 to study factors contributing to cardiovascular disease progresStudy of Atherosclerosis (MESA) cohort, a large longitudinal cohort established in 2000 to study factors contributing to cardiovascular disease progresstudy factors contributing to cardiovascular disease progression.

The results from this cohort will help us evaluate what is the optimal dose for a future, larger clinical study.

Data shared through RD ‐ Connect is accessible beyond the usual institutional and national boundaries and researchers across the world can benefit from the opportunity to work with others with an interest in the same field, pool data to create larger cohorts, find confirmatory cases, and access samples for further study.

Our study has several strengths despite the limitations, including population - based identification of cases from a large birth cohort and the use of prospectively collected information on influenza infection and vaccination documented in medical records.

The LEAP study, designed and conducted by the ITN with additional support from FARE and led by Professor Gideon Lack at Kings College London, is the first randomized trial to prevent food allergy in a large cohort of high - risk infants.

Conversely, within non-diabetic populations, periods of IER (75 - 85 % ER on restricted days) do not typically affect fasting glucose levels 37, 41, 45, 48 or HbA1c 41, 48; results of which can often be replicated by short term CER studies.62 - 65These findings are unsurprising given that frank hyperglycaemia within the T2DM diagnostic range is effectively a late - stage manifestation of IR, which along with compensatory increases insulin secretion, can precede the onset of T2DM by many years.66, 67 Findings from one large scale prospective cohort study, Whitehall II, reveal a sharp increase in the trajectory towards fasting hyperglycaemia which is only detectable three years prior to diagnosis with T2DM.67 Consequently, it can be argued that changes in circulating insulin concentrations, fasting (hepatic) insulin sensitivity and glucose uptake / clearance are more sensitive markers of deteriorating glucose control than fasting glycaemia in non - diabetics.68 - 70

, Maternal caffeine intake during pregnancy is associated with birth weight but not with gestational length: results from a large prospective observational cohort study, 2013

Looking at 3 large prospective cohorts (Nurses Health Study 1 and 2, and the Health Professional Follow Up), the researchers from Harvard looked at the risk of type 2 diabetes with the consumption of whole fruits and fruit juice.

Yet the reduction in LDL cholesterol from reducing saturated fat intake seems to be specific to large, buoyant (type A) LDL particles, when in factit is the small, dense (type B) particles (responsive to carbohydrate intake) that are implicated in cardiovascular disease.Indeed, recent prospective cohort studies have not supported any significant association between saturated fat intake and cardiovascular risk Instead, saturated fat has been found to be protective.»

And claiming that, because they are not considered paleo foods by your favourite gurus, it must mean grains and legumes are bad for us simply flies in the face of the evidence: «In summary, these data from 2 large prospective cohort studies consistently found significant inverse associations of whole grain intake and mortality, especially CVD mortality.

Maternal caffeine intake during pregnancy and childhood growth and overweight: results from a large Norwegian prospective observational cohort study, BMJ Open, published online.

One of the largest association studies of the recent past has come from analysis of the data by combining three very large cohort studies — the Nurses Health Studies I and II as well as the Health Professional's Follow Upstudies of the recent past has come from analysis of the data by combining three very large cohort studies — the Nurses Health Studies I and II as well as the Health Professional's Follow Upstudies — the Nurses Health Studies I and II as well as the Health Professional's Follow UpStudies I and II as well as the Health Professional's Follow Up study.

Researchers from Harvard looked at the data from 3 large prospective cohorts (Nurse's Health Study 1 and 2, and the Health Professionals Follow Up).

20Sengpiel V. et al. (2013) Maternal caffeine intake during pregnancy is associated with birth weight but not with gestational length: results from a large prospective observational cohort study.

Analyses were conducted using public - use data available from the Fragile Families and Child Wellbeing Study, a prospective birth cohort study that follows up a nationally representative sample of children from 20 large cities in the United StStudy, a prospective birth cohort study that follows up a nationally representative sample of children from 20 large cities in the United Ststudy that follows up a nationally representative sample of children from 20 large cities in the United States.

In a retrospective cohort study set in a primary care clinic for adult members of a large health maintenance organization, questionnaire responses from 4127 men were analyzed.

Recently, a research team from Denmark performed a large population - based and register - based prospective cohort study to shed further light on this compelling issue.13 Researchers included only singleton births in a 10 - year period, and excluded conditions associated with an increased risk of ASDs (eg, congenital rubella syndrome or some genetic disorders in parents).

One, the primary source in this review, is the Fragile Families and Child Wellbeing Study (FFCWS), which offers data on parents of children born in urban hospitals in twenty large cities between 1998 and 2000.7 A second is the National Longitudinal Survey of Youth (especially the 1979 panel, NLSY79), which now provides data from 1979 to 2006 on the cohort of individuals aged fourteen to twenty - one in 1979.

This large, retrospective cohort study — constructed from linked, administrative data — will include an almost complete population of children born in the state of New South Wales, Australia; this will enable investigation of small population groups, such as Aboriginal children, and minimise selection bias.

Relations between symptoms of ADHD reported in the Preschool Age Psychiatric Assessment interview (PAPA), and EF as measured by the BRIEF - P (parent form), were investigated in a large, nonreferred sample of preschool children (37 — 47 months, n = 1134) recruited from the Norwegian Mother and Child Cohort Study (MoBa) at the Norwegian Institute of Public Health.

This is a secondary analysis of data from the Fetal Programming Study [63], a sub-study of the larger Alberta Pregnancy Outcomes and Nutrition (APrON) longitudinal pregnancy cohort sStudy [63], a sub-study of the larger Alberta Pregnancy Outcomes and Nutrition (APrON) longitudinal pregnancy cohort sstudy of the larger Alberta Pregnancy Outcomes and Nutrition (APrON) longitudinal pregnancy cohort studystudy.