The most influential evidence came
from large prospective cohort studies conducted over the past 20 years.
Not exact matches
The
prospective study included 23,928 participants without coronary heart disease
from Reasons for Geographic and Racial Differences in Stroke (REGARDS), a
large biracial population - based
cohort study.
Nechuta and colleagues used data
from the Shanghai Women's Health
Study, a large, population - based prospective cohort study of about 75,000 women ages 40 to 70, from Shanghai, China, led by Wei Zheng, MD, PhD, at the Vanderbilt Epidemiology Ce
Study, a
large, population - based
prospective cohort study of about 75,000 women ages 40 to 70, from Shanghai, China, led by Wei Zheng, MD, PhD, at the Vanderbilt Epidemiology Ce
study of about 75,000 women ages 40 to 70,
from Shanghai, China, led by Wei Zheng, MD, PhD, at the Vanderbilt Epidemiology Center.
Conversely, within non-diabetic populations, periods of IER (75 - 85 % ER on restricted days) do not typically affect fasting glucose levels 37, 41, 45, 48 or HbA1c 41, 48; results of which can often be replicated by short term CER studies.62 - 65These findings are unsurprising given that frank hyperglycaemia within the T2DM diagnostic range is effectively a late - stage manifestation of IR, which along with compensatory increases insulin secretion, can precede the onset of T2DM by many years.66, 67 Findings
from one
large scale
prospective cohort study, Whitehall II, reveal a sharp increase in the trajectory towards fasting hyperglycaemia which is only detectable three years prior to diagnosis with T2DM.67 Consequently, it can be argued that changes in circulating insulin concentrations, fasting (hepatic) insulin sensitivity and glucose uptake / clearance are more sensitive markers of deteriorating glucose control than fasting glycaemia in non - diabetics.68 - 70
, Maternal caffeine intake during pregnancy is associated with birth weight but not with gestational length: results
from a
large prospective observational
cohort study, 2013
Looking at 3
large prospective cohorts (Nurses Health
Study 1 and 2, and the Health Professional Follow Up), the researchers
from Harvard looked at the risk of type 2 diabetes with the consumption of whole fruits and fruit juice.
Yet the reduction in LDL cholesterol
from reducing saturated fat intake seems to be specific to
large, buoyant (type A) LDL particles, when in factit is the small, dense (type B) particles (responsive to carbohydrate intake) that are implicated in cardiovascular disease.Indeed, recent
prospective cohort studies have not supported any significant association between saturated fat intake and cardiovascular risk Instead, saturated fat has been found to be protective.»
And claiming that, because they are not considered paleo foods by your favourite gurus, it must mean grains and legumes are bad for us simply flies in the face of the evidence: «In summary, these data
from 2
large prospective cohort studies consistently found significant inverse associations of whole grain intake and mortality, especially CVD mortality.
Maternal caffeine intake during pregnancy and childhood growth and overweight: results
from a
large Norwegian
prospective observational
cohort study, BMJ Open, published online.
Researchers
from Harvard looked at the data
from 3
large prospective cohorts (Nurse's Health
Study 1 and 2, and the Health Professionals Follow Up).
20Sengpiel V. et al. (2013) Maternal caffeine intake during pregnancy is associated with birth weight but not with gestational length: results
from a
large prospective observational
cohort study.
Analyses were conducted using public - use data available
from the Fragile Families and Child Wellbeing
Study, a prospective birth cohort study that follows up a nationally representative sample of children from 20 large cities in the United St
Study, a
prospective birth
cohort study that follows up a nationally representative sample of children from 20 large cities in the United St
study that follows up a nationally representative sample of children
from 20
large cities in the United States.
Recently, a research team
from Denmark performed a
large population - based and register - based
prospective cohort study to shed further light on this compelling issue.13 Researchers included only singleton births in a 10 - year period, and excluded conditions associated with an increased risk of ASDs (eg, congenital rubella syndrome or some genetic disorders in parents).