Sentences with phrase «from large trials»

We will know more later this year, when the results from a large trial that addresses exactly this question will be published.

Now, six years after insulin - producing cells were first transplanted into people with diabetes, results from the largest trial yet of the «Edmonton protocol» are in.

More information may come from another large trial Ridker is running.

We will know more later this year, when the results from a large trial addressing this question will be published.

But this won't become clear until the results from larger trials are in.

The researchers drew patients from a large trial focusing on the use of CCTA in people who had come to the emergency department with acute chest pain.

Not exact matches

While the new mid-stage study results from DNDi were impressive (they showed cure rates of 96 % to 97 % even for the sickest patients and those with liver scarring), more late - stage trials will be necessary before the drug is available on a large scale in the developing world.

While there were dissenters, the Supreme Court found that Skilling's negative publicity didn't prevent him from receiving a fair trial — especially because Houston was the fourth - most - populous city in the country, allowing for a large jury pool.

The 5G plan announced on Tuesday by the third - largest wireless carrier stands in start contrast to the emphasis from bigger competitors Verizon (vz) and AT&T, which are both running trials for fixed wireless Internet service using 5G to serve homes and businesses.

Most death penalty cases, from trials to appeals, rack up a large bill for multiple state agencies.

These risks and uncertainties include: Gilead's ability to achieve its anticipated full year 2018 financial results; Gilead's ability to sustain growth in revenues for its antiviral and other programs; the risk that private and public payers may be reluctant to provide, or continue to provide, coverage or reimbursement for new products, including Vosevi, Yescarta, Epclusa, Harvoni, Genvoya, Odefsey, Descovy, Biktarvy and Vemlidy ®; austerity measures in European countries that may increase the amount of discount required on Gilead's products; an increase in discounts, chargebacks and rebates due to ongoing contracts and future negotiations with commercial and government payers; a larger than anticipated shift in payer mix to more highly discounted payer segments and geographic regions and decreases in treatment duration; availability of funding for state AIDS Drug Assistance Programs (ADAPs); continued fluctuations in ADAP purchases driven by federal and state grant cycles which may not mirror patient demand and may cause fluctuations in Gilead's earnings; market share and price erosion caused by the introduction of generic versions of Viread and Truvada, an uncertain global macroeconomic environment; and potential amendments to the Affordable Care Act or other government action that could have the effect of lowering prices or reducing the number of insured patients; the possibility of unfavorable results from clinical trials involving investigational compounds; Gilead's ability to initiate clinical trials in its currently anticipated timeframes; the levels of inventory held by wholesalers and retailers which may cause fluctuations in Gilead's earnings; Kite's ability to develop and commercialize cell therapies utilizing the zinc finger nuclease technology platform and realize the benefits of the Sangamo partnership; Gilead's ability to submit new drug applications for new product candidates in the timelines currently anticipated; Gilead's ability to receive regulatory approvals in a timely manner or at all, for new and current products, including Biktarvy; Gilead's ability to successfully commercialize its products, including Biktarvy; the risk that physicians and patients may not see advantages of these products over other therapies and may therefore be reluctant to prescribe the products; Gilead's ability to successfully develop its hematology / oncology and inflammation / respiratory programs; safety and efficacy data from clinical studies may not warrant further development of Gilead's product candidates, including GS - 9620 and Yescarta in combination with Pfizer's utomilumab; Gilead's ability to pay dividends or complete its share repurchase program due to changes in its stock price, corporate or other market conditions; fluctuations in the foreign exchange rate of the U.S. dollar that may cause an unfavorable foreign currency exchange impact on Gilead's future revenues and pre-tax earnings; and other risks identified from time to time in Gilead's reports filed with the U.S. Securities and Exchange Commission (the SEC).

«[A.I.] can help analyze large data sets from sources such as clinical trials, health records, genetic profiles, and preclinical studies; within this data, it can recognize patterns and trends and develop hypotheses at a much faster rate than researchers alone,» says Deloitte.

We talk with two pioneering physicians — one of whom is overseeing the world's largest HIV vaccine trial and the other led a groundbreaking successful pilot in the U.S. — to see how far we are from getting to zero.

* MEDICINES360 AND ALLERGAN PRESENT 5 - YEAR TRIAL DATA FROM LARGEST ON - GOING IUS CLINICAL STUDY Source text for Eikon: Further company coverage:

The adaptive pathways concept applies primarily to treatments in areas of high medical need where it is difficult to collect data via traditional routes and where large clinical trials would unnecessarily expose patients who are unlikely to benefit from the medicine.

As the trial of the head of one of South Korea's largest conglomerates on corruption charges got underway, the president's ousting meant she lost her immunity to prosecution over the corruption scandal that forced her from office.

It's also a game that became dangerous for me when it introduced online rankings, as I could not stop playing once I noticed where I ranked in North America on time trial courses from the Wii edition — it was that experience with the time trials mode from my youth all over again, except instead of just besting myself and my dad and a couple of friends, it was a large percentage of a continent that I'm embarrassed to even quote here as it will give away just how time I spent with the game.

The large LEAP trial saw that exposure beginning anywhere from 4 — 11 months old was associated with a lower risk of peanut allergy.

Previous trials included a very large plastic lidded basket intended for storing soiled cloth diapers that came complimentary from the diaper service we used when our first son was born.

Much of the evidence against BPA comes from large population studies rather than controlled clinical trials.

Clearly, additional large randomize trials are needed to further understand the possibility of using probiotics to manage infant colic crying and which subgroup of infant could potentially profit from such intervention.

We used data from a large cluster - randomized trial to assess the impact of a breastfeeding promotion intervention on socioeconomic inequalities in breastfeeding (exclusivity and duration) and in child cognitive ability at early school age.

Although some of the enthusiasm for home visiting has waned in the past decades as reports of some large randomized trials have failed to demonstrate program effects, evidence from other programs targeted for families at risk (eg, low - income families) has shown enough promise to build on program development momentum.

«Our results justify the need for a large - scale trial of lactoferrin, as well as its counterpart derived from cow milk, bovine lactoferrin.»

Randomised controlled trial of women in attending antenatal care at a large hospital to receive 1 of 3 support strategies from late pregnancy (32 - 26 weeks) to 3 months postpartum: cell phone based peer support (CPS) or monthly peer - led support groups (PSG) or Control

Breastfeeding and child cognitive development: new evidence from a large randomized trial.

In addition, there was no effect on breastfeeding duration when the pacifier was introduced at 1 month of age.280 A more recent systematic review found that the highest level of evidence (ie, from clinical trials) does not support an adverse relationship between pacifier use and breastfeeding duration or exclusivity.281 The association between shortened duration of breastfeeding and pacifier use in observational studies likely reflects a number of complex factors such as breastfeeding difficulties or intent to wean.281 A large multicenter, randomized controlled trial of 1021 mothers who were highly motivated to breastfeed were assigned to 2 groups: mothers advised to offer a pacifier after 15 days and mothers advised not to offer a pacifier.

In a large randomised controlled trial from Helsinki, 4 9000 women were randomly divided into two groups.

This study is a sub-sample of results from a larger study and the outcomes reported in the trial registration document are not reported in this study, However, the full study results have not yet been published to be able to judge this outcome.

Another perennial top - finisher, the state's largest trial lawyers» group was involved in issues in 2016 ranging from the Scaffold Law to the expansion of ride - hailing.

Aubry also netted $ 6,100, his largest contribution, from the New York Trial Lawyers Association's political action committee, Lawpac of New York; $ 3,800 from Jeffrey Gural of real estate agency Newmarket Knight Frank in Manhattan; and $ 2,500 from Beverly's Home Care Agency in Rego Park.

From 1996 to 2001, he was Director of the U.S. National Institute of Mental Health (NIMH), where he emphasized investment in neuroscience and emerging genetic technologies, and initiated a series of large practical clinical trials to inform practice.

They conducted a large controlled trial of 1,200 students aged 14 - 16 in 70 classes from secondary schools across the south and south west of the UK, in which students were tested for acceptance of evolution and understanding of evolution and, as a control subject, genetics.

The investigators mined genetic data from large clinical trials to find individuals with naturally occurring mutations in the NPC1L1 gene that completely shut it down.

From here, we'll be optimizing the delivery system, evaluating the approach in more severe models of DMD, and assessing efficiency and safety in larger animals with the eventual goal of getting into clinical trials.»

Stitziel and his colleagues pointed out that this question will be addressed later this month with the reporting of results from a large clinical trial called IMProved Reduction of Outcomes: Vytorin Efficacy International Trial (IMPROVE -trial called IMProved Reduction of Outcomes: Vytorin Efficacy International Trial (IMPROVE -Trial (IMPROVE - IT).

They found that in the U.S., but not elsewhere, trials are becoming longer (from an average of four - weeks long in 1990 to 12 weeks in 2013) and larger (from an average of fewer than 50 patients in 1990 to an average of more than 700 patients in 2013).

That's because a trial like this one is almost without precedent in modern medical research: It involves giving children a vaccine that is almost certain not to benefit them, and that might harm them, all to protect other children from an unlikely scenario — a large - scale anthrax attack.

Carl E. Clarke, M.D., of the University of Birmingham, England, and coauthors conducted a large clinical trial to evaluate the effectiveness of PT and OT in 762 patients with mild to moderate PD who were recruited from 38 sites across the United Kingdom.

To identify the relevant mutations the scientists analyzed the blood samples of 1,858 men from three independent cohorts in Europe and North America: the Swiss arm of the European Randomized Study for Prostate Cancer Screening, the large American Screening trial, Prostate, Lung, Colorectal, and Ovarian (PLCO), Princess Margaret Cancer Centre (University Health Network) and Mount Sinai Hospital (Sinai Health System) in Toronto.

«It was clear from our findings that many people with IBS should have their vitamin D levels tested, and the data suggests that they may benefit from supplementation with vitamin D. «As a result of this exploratory study, we're now able to design and justify a larger and more definitive clinical trial.»

Wyss - Coray, whose group did most of the mouse studies that inspired the clinical trial, now plans to conduct a second, larger trial using plasma from which many proteins and other molecules have been removed.

The company is starting larger trials to see if the vaccine can actually protect people from getting sick.

A statin drug commonly used to lower cholesterol is not effective in reducing the number and severity of flare ups from chronic obstructive pulmonary disease (COPD), according to the results of a large multicenter clinical trial designed and directed by Gerard J. Criner, MD, Director of Pulmonary and Critical Care Medicine at Temple University Hospital in Philadelphia, PA..

In 2011, Science's editors will be watching a smaller detector at the Large Hadron Collider called LHCb, which will study B mesons in great detail; new techniques that should lead to the discovery of many more genes contributing to adaptation; an ignited fusion burn at the National Ignition Facility; broadly neutralizing antibodies, which are capable of disabling a wide range of viral variants; the first plug - in hybrid electric cars whose batteries are charged from a wall socket go on the market; and the results of the first phase III trial of a malaria vaccine.

Writing in a linked Comment, Christopher Colvin from the University of Cape Town in South Africa, and Abigail Harrison from Brown University School of Public Health in the USA say, «Currently, the increasingly narrow and fierce debates over the HIV and depot medroxyprogesterone acetate link have focused on whether a large randomised controlled trial should be done to better understand this link.

In one trial, the research team selectively removed the largest species of coral guard - crab, T. flavopunctata, from corals in the path of the army of sea stars and observed the effects.

To test the potential benefit and safety of targeted hypothermia in donors on delayed organ function rates in the recipients of their kidneys, Niemann and his research team conducted a randomized controlled trial in two large organ donation service areas from March 2012 to October 2013.

If enacted, such a regulatory scheme could conceivably speed along clinical trials because it would allow investigators to draw from a large pool of people with diverse tumors that act along the same pathway instead of culling thousands of people with the same official cancer type.

Today's catch phrase is «evidence - based medicine,» and that «evidence» typically takes the form of results from clinical trials, in which potential treatments are tested on large groups of people.