Sentences with phrase «from luminal»

In addition, curcumin significantly improves barrier function, reducing translocation of lipopolysaccharide (LPS), the outer cell wall of gram - negative bacteria, from the luminal surface of the intestine into circulation (Ghosh et al., 2014).

Research has revealed that omega - 3 fatty acids are more effective in stopping or slowing the growth in the number of triple - negative breast cancer cells in comparison to cells from luminal categories of breast cancer.

Remarkably, down - regulation of MELK led to a substantial regression of tumors arising from BBC cells but had little effect on tumors derived from luminal cancer cells (Figure 7C, D, Figure 7 — figure supplement 1).

Previous work led by Charlotte Kuperwasser, principal investigator, determined that some common forms of breast cancer originate from luminal cells while some rarer forms of breast cancer originate from basal cells.

Not exact matches

The team also looked at the levels of the TAZ gene in tumors from women with either luminal or basal tumors.

«We note that there are two subgroups of breast tumors by epigenome: one which we have called Epi - Basal, characterized by loss of epigenetic marks causing breakage of chromosomes and the other that we have called Epi - Luminal B, that presents epigenetic inactivation of genes that should protect us from cancer and these altered cells can no longer do it.»

The Tufts team discovered that luminal - like breast cancers (the two most common types, and which are sensitive to hormones) originate from self - renewing cells known as lobule progenitors.

Cells from basal cancers are able to switch relatively easily into cancer stem cell (CSC) state, unlike luminal breast cancer cells, which tend to remain in the non-CSC state.

Primary kidney epithelial cells isolated from human proximal tubule are cultured on the upper surface of an extracellular matrix - coated, porous, polyester membrane that splits the main channel of the device into two adjacent channels, thereby creating an apical «luminal» channel and a basal «interstitial» space.

(C and D) Effects of MELK knockdown on established tumors arising from implantation of basal (C) or luminal (D) breast cancer cells.

P - glycoprotein is present on the luminal border of these intestinal epithelial cells where it transports drugs from the cytoplasm back into the intestinal lumen where they can be eliminated.

Proposed causes for human IBD include defective immunoregulation of the gut - associated lymphoid tissue that may be precipitated by permeability defects, 14 infectious and parasitic agents, 15,16 and dietary allergies.13, 17 There is provocative evidence from clinical observations and animal models to incriminate normal luminal bacteria or bacterial products in the initiation and perpetuation of canine IBD.18, 19 The clinical response to hypoallergenic or elimination diets suggest that dietary factors may influence the pathogenesis of canine IBD.8 - 11 The term «hypoallergenic» refers to a diet that is generally free of additives and preservatives, and contains a hydrolyzed protein source.