Sentences with phrase «from lung tumors»

Not exact matches

Potti and his colleagues began by testing chemotherapy drugs on cultured cell lines from human tumors, such as from the lung, breast, or ovary.

Then there was the researcher, just back from Myanmar, panicked about a tumor in his lung.

They found out that TiY is capable of distinguishing TICs from non-TICs in various human lung cancer cell lines and patient - derived lung tumors.

The substance vigorously inhibited the growth of cultured tumor cells from colon, lung, and breast cancers, the team reports in the 20 January issue of Angewandte Chemie.

The researchers confirmed their observations by studying tissue from lung cancer tumors.

«FDG PET shows tumor DNA levels in blood are linked to NSCLC aggressiveness: Insights derived from FDG PET could improve treatment selection for patients with advanced non-small cell lung cancer.»

Loss of either GSTO1 or RYR1, the researchers report, decreased the number of cancer stem cells in the primary tumor, blocked metastasis of cancer cells from the primary tumor to the lungs, decreased the duration of chemotherapy required to induce remission and increased the duration of time after chemotherapy was stopped that the mice remained tumor - free.

Nana - Sinkam and his colleagues examined lung - tumor samples from 81 patients with stage - 1 nonsmall - cell lung cancer and tumor - cell lines.

But tumors from patients with distant metastases to the lung and liver showed massive epigenetic changes that mapped to large, blocklike segments of the genome, both in the distant metastases themselves and in the section, or «subclone,» of the primary tumors they came from.

«High concordance between EGFR mutations from circulating - free tumor DNA and tumor tissue in non-small cell lung cancer.»

Epidermal growth factor receptor (EGFR) mutations found in the circulating free tumor DNA (ctDNA) from the plasma of advanced non-small cell lung cancer (NSCLC) patients correlates well with the EGFR mutations from patient - matched tumor tissue DNA.

P: We found discodermolide [a drug from Discodermia, a sponge found in the Caribbean, the Bahamas, and the Gulf of Mexico], and it's gone through phase I clinical trials for treatment of solid tumors such as ovarian, pancreatic, breast, colon, or lung cancers.

Various genetic testing methods were used to examine lung tumors, uninvolved lung tissue and normal - appearing airways located varying distances from the tumors.

«Almost half the deaths from cancers result from lung and breast cancer, both of which are solid tumors.

In the Dec. 1 issue of Science, the team from the MGH Center for Systems Biology describes a «crosstalk» between lung tumors and bone marrow, which leads to the generation of a type of immune cell that travels to the tumor and promotes its progression.

When the researchers removed FAK from blood vessels that grew in melanoma or lung cancer models, both chemotherapy and radiation therapies were far more effective in killing the tumors.

Results of an initial study of tumors from patients with lung cancer or head and neck cancer suggest that the widespread acquired resistance to immunotherapy drugs known as checkpoint inhibitors may be due to the elimination of certain genetic mutations needed to enable the immune system to recognize and attack malignant cells.

«For example, mouse mammary tumors shared a signaling pathway that is found in human lung cancer and controls how cells reproduce and move from one location to another.»

The current clinical trial uses information of air movement from existing 4D CT data and «some equations,» says Vinogradskiy (diplomatically) to calculate lung function in tissue surrounding tumors.

The results from our new study suggest that entinostat may enhance the anti-tumor efficacy of PD - 1 targeted therapy through MDSC targeting, potentially providing an effective combination treatment approach for patients with solid tumors, including lung and renal cell carcinoma.»

In one, a liver and armpit tumor that had developed from spreading melanoma cells shrank, and in the other a lung tumor disappeared.

«Metastatic brain tumors — often from lung, breast or skin cancers — are the most commonly observed tumors within the brain and account for about 40 percent of advanced melanoma metastases.

Another replication attempt supported a 2011 Science Translational Medicine report from Stanford computational biologist Atul Butte's lab that the ulcer drug Tagamet slows the growth of lung tumors in mice.

«Metastatic brain tumors — often from lung, breast or skin cancers — are the most commonly observed tumors within the brain and account for about 30 percent of advanced breast cancer metastases,» says Khalid Shah, MS, PhD, director of the Molecular Neurotherapy and Imaging Laboratory in the MGH Departments of Radiology and Neurology, who led the study.

In these circumstances, cells from primary tumors in breast, colon, prostate, or other organs invade lung tissue via the bloodstream.

An anti-PD-1 antibody developed by Bristol - Myers Squibb generates excitement with results from a phase I trial showing that, among 236 patients with various types of cancer, the treatment shrank tumors in 28 percent of melanoma patients, 30 percent of patients with kidney cancer, and 18 percent of patients with advanced non-small cell lung cancer.

IHC - P mouse tumor tissue (from lung) with human cell line injected, some muscle tissue attached as well sees high background for human cellswith priamry Ab as well as isotype ctrl, but also for muscle (does not contain any EGF) Ab: 1 ug /...

Surgery for carcinoid tumor of the lung hasn't prevented John Williams from taking 15 - mile bike rides «without a problem.»

The team examined premalignant as well as cancer cells from breast and lung tumors and matched normal and premalignant breast cells from healthy women provided by scientists at the University of California San Francisco.

Five to six weeks after the resection of primary tumors from tumor - bearing NOD / SCID mice, lungs were harvested and fixed in the Bouin's fixative solution overnight.

The sum of metastatic tumor volume was first calculated from four lobes of lungs per animal (see Materials and methods), and the lung metastasis per group is presented as tumor volume (cubic millimeters).

With the recent presentation of the data from Keynote - 024, and the recent approval of pembrolizumab for high PD - L1 expressing tumors, the landscape of lung cancer oncology will change dramatically and for the better.

In this fashion, they derive a signal from the tumor cells proportional to tumor mass which arises spontaneously in vivo in the accurate setting of the lung and from the accurate genetic lesions found in human non-small cell lung cancer (NSCLC).

Lung metastases from the tumor - initiating assays.

A CT scan showed tumors ranging in size from 0.4 to 4.4 centimeters in his neck, lymph nodes, lungs and liver.

Tens of thousands of Americans with tumors from certain types of lung cancer have mutations that might be treated by...

Most tumors contain fewer than 10 of the driver mutations, but the number of total mutations — passenger and driver — can climb far higher, from a dozen or so in neuroblastoma to approximately 200 in lung cancer.

Metastatic tumor burden of each animal was calculated by combining tumor volumes from four lobes of lungs.

These interests grew from studies of paraneoplastic neurologic disorders (PNDs), a group of diseases thought to arise when tumors — typically breast, ovarian, or lung cancers — start making proteins normally only made by the brain.

A new biomarker is 98 percent effective at distinguishing benign from malignant lung tumors.

DNA Detectives Find Genetic Markers for Lung Cancers Most Likely to Recur Researchers at the Johns Hopkins Kimmel Cancer Center uncovered clearly recognizable genetic alterations in tumors and tissue removed from patients with early - stage lung cancers that look like good predictors of which of these cancers are more likely to reLung Cancers Most Likely to Recur Researchers at the Johns Hopkins Kimmel Cancer Center uncovered clearly recognizable genetic alterations in tumors and tissue removed from patients with early - stage lung cancers that look like good predictors of which of these cancers are more likely to relung cancers that look like good predictors of which of these cancers are more likely to recur.

The Program specializes in the treatment of primary head and neck cancers, brain and spine tumors such as squamous cell carcinoma, basal cell cancer, glomus tumor, paragangliomas, acoustic neuromas, salivary gland and mucosal tumors, astrocytomas, oligodendrogliomas, glioblastomas, and hemangioblastomas, and metastatic tumors that may have arisen from elsewhere in the body such as the breast, lung, or prostate.

The company's initial goal is to identify and deploy therapeutic neo-antigens from individual patients» tumors to develop novel treatments for lung cancer.

One example: In stage 4 breast cancer, the tumor may have spread from the breast to the bones, brain, liver, or lungs.

A 2012 Japanese study found the pulp and juice from satsuma mandarin oranges inhibited tumor growth in cancers of the colon, lung and tongue.

What I learned from the supervising vet was that 50 % of those malignant mammary tumors have already metastasized to the lungs by the time of diagnosis.

The blood can be coming from your dog's lungs, pharynx, esophagus, stomach, or upper (small) intestine and this can mean a serious disorder such as a tumor.

These diseases include infectious pneumonia (fungal, bacterial, parasitic), feline heartworm disease (cats are aberrant hosts for the canine heartworm disease parasite), primary lung parasites, and tumor disease (either a lung tumor, or one that has metastasized or spread to the lungs from elsewhere in the body).

Another main trigger is the involuntary movement of the hairlike cilia in the respiratory tract which remove foreign matter from the air before it gets into the lungs, but other underlying causes can include mucous irritation, obstruction of the nasal passage, inflammation, excess nasal discharge or secretion, pneumonia, chronic vomiting, GI disease, and nasal tumors and dental diseases in older dogs.

These secondary or metastatic tumors are sometimes difficult to distinguish from multiple tumors originating in the lung.