Sentences with phrase «from lysosomes»

Not exact matches

Derived from Greek terms meaning «self - eating,» the autophagy system sends protein aggregates and malfunctioning cellular components into acidic compartments called lysosomes, where enzymes chew them up.

Osmotic release of β - glucuronidase from polymorphonuclear leukocyte lysosomes is inhibited by catecholamines and adenosine 3», 5» - monophosphate, and accelerated by cholinergic agents and guanosine 3», 5» - monophosphate.

Multivalent immune complexes divert FcRn to lysosomes by exclusion from recycling sorting tubules.

Early Delivery of Misfolded PrP from ER to Lysosomes by Autophagy.

Lysosomes are responsible for the turnover and clearance from cells of damaged organelles and protein aggregates.

We describe here that in cells derived from human monocytes, i.e., macrophages and dendritic cells, the B - subunit was internalized in a receptor - dependent manner, but retrograde transport to the biosynthetic / secretory pathway did not occur and part of the internalized protein was degraded in lysosomes.

Autophagy describes how cells replace themselves and their components over time; in scientific language, it is the process whereby cytoplasmic components are isolated from the rest of the cell within autophagosomes, which are then fused with lysosomes and degraded.

So he took me for a summer and I learned to isolate lysosomes from cells using his method and looked at if the two systems we were studying were the same.»

PV - 10 (rose bengal disodium 10 %), a small - molecule fluorescein derivative, while excluded from normal cells, transits the plasmalemma of cancer cells and accumulates in lysosomes, triggering lysosomal release and complete autolysis within 30 to 60 minutes.

By trapping the drug within lysosomes, cancer cells were able to prevent the chemotherapy from reaching its target, effectively neutralizing the drug.