Sentences with phrase «from mouse stem»

The milestones of the two - year project include generating engineered exosomes from mouse stem cells and evaluating their potential to fuse with the GnRH cells.

Researchers have successfully created functional sperm cells from mouse stem cells in the laboratory, then implanted those cells into rodents» egg cells to produce healthy, fertile offspring.

Researchers from Japan's RIKEN institute announced in April that they have grown skin from mouse stem cells in a process that one day may help skin graft recipients.

«Physical forces are certainly a factor in getting the lung lining to be fully functional,» says Anne Bishop at Imperial College London, who has made alveolar cells from mouse stem cells using growth factors alone.

Not exact matches

The embryos, which were genetically modified to prevent them from growing their own pancreases, were injected with mouse pluripotent stem cells that formed into a pancreas.

The new tissue wasn't rejected since they stemmed from the mice's cells in the first place.

«What made sense from an R&D perspective, in terms of our understanding of mouse stem cells, made total sense from a product perspective if you realize our customers are cats,» Bethencourt says.

In 2010, researchers from the University of Michigan Comprehensive Cancer Center published a study in the journal Clinical Cancer Research showing that sulforaphane had the ability to kill breast cancer stem cells in mice and in lab cultures, and it also prevented the growth of new tumor cells.

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This need stems from the mammalian brain, a commonality that affects cats, dogs, mice... and humans!

In the March 22 online issue of Cancer Research, scientists explained how they injected triple negative breast cancer stem cells from patients into mice.

Injections of killed stem cells, designed to help the immune system recognise cancers, have been found to protect mice from developing tumours

Once a gene is gone, researchers grow mice from the stem cells to see what happens.

To see whether this also applies to humans, the team engineered stem cells from people with and without Down's syndrome and injected them into mice.

The researchers confirmed this hypothesis by showing that if they blocked YAP1 they could inhibit stem cells from undergoing self - renewal, forming blood vessel - like structures, and reduce lung cancer cell growth in mice.

And the transformed cells proved to be very similar to actual stem cells from both mice and humans.

After receiving an injection of neural stem cells from young mice, however, they performed as well as healthy mice did.

Stem cells created from unfertilized mice eggs are successfully transplanted without immune rejection

He and his boss, stem cell researcher Donald Phinney, wondered whether those mice were also protected from the fattening of the bone marrow that accompanies a high - fat diet.

In experiments on normal and MLL cells from mice and humans, the researchers demonstrated that beta - catenin is activated in cancer stem cells that prompt leukaemic blood cells to multiply.

Currently, Deng's laboratory is conducting additional preclinical studies using the human - derived stem cells from Down syndrome patients and mouse models to determine whether cellular and behavioral abnormalities can be improved with minocycline therapy and other candidate drugs.

By promoting DNA demethylation, high - dose vitamin C treatment induced stem cells to mature, and also suppressed the growth of leukemia cancer stem cells from human patients implanted in mice.

Current research is looking at why inhibiting certain molecules, such as mouse protein Stat3, promote muscle regeneration in mice and how to engineer orthopedic implants from stem cells to replace damaged cartilage and bone, but the results of that effort aren't expected to be necessarily aimed at the old.

But in this case, the undifferentiated stem cells, harvested from 14 - day - old mouse brains, did not simply replace neurons that had died off.

«When we transplanted our labeled blood stem cells from the bone marrow into other mice, only a few stem cells were active in the recipients, and many stem cells were lost,» Rodewald explains.

Scientists have previously shown that isolated germline stem cells from mice can turn into eggs in a petri dish.

Dr. Katrin Busch from Rodewald's team developed genetically modified mice by introducing a protein into their blood stem cells that sends out a yellow fluorescent signal.

For one study in 2012 in Frontiers in Immunology, scientists from Canada injected these stem - recognizing antibodies into mice to see if the mice were shielded from a different strain of flu.

The two reports also showed that Zika virus infected and damaged neuronal stem cells harvested from mice and humans.

Scientists from the German Cancer Research Center (DKFZ) have developed a way to equip mouse blood stem cells with a fluorescent marker that can be switched on from the outside.

In July 2006, biologist Karim Nayernia at the University of Newcastle - upon - Tyne in the UK, and colleagues reported they had successfully converted stem cells from mouse embryos into functioning sperm that could fertilise mouse eggs and produce live offspring.

During embryonic development of mice, however, the situation is different: To build up the system, all mature blood and immune cells develop much more rapidly and almost completely from stem cells.

The mice benefited from human stem cells called glial progenitors, immature cells poised to become astrocytes and other glia cells, the supposed support cells of the brain.

For his prototype he is growing mouse muscle from stem cells in a petri dish.

A subset of the implanted human stem cells matured into rotund, humanlike astrocytes in the animals» brains, taking over operations from the native mouse astrocytes.

In a related paper published online today in Nature Biotechnology, Konrad Hochedlinger of the Harvard Stem Cell Institute in Cambridge and his colleagues compared the gene expression patterns in mouse iPS cells derived from white blood cells, muscle precursor cells, immune system cells called B cells, and fibroblasts taken from tail tips.

The research team used mass spectrometry to compare phosphorylation of proteins from mouse embryonic stem cells with fully functioning GSK - 3 to cells in which the gene encoding GSK - 3 had been deleted.

Transplants grown from stem cells in the lab can help replenish the blood and have been used to cure anaemia in mice.

Loss of either GSTO1 or RYR1, the researchers report, decreased the number of cancer stem cells in the primary tumor, blocked metastasis of cancer cells from the primary tumor to the lungs, decreased the duration of chemotherapy required to induce remission and increased the duration of time after chemotherapy was stopped that the mice remained tumor - free.

These organoids had more stem cells than those isolated from wild - type mice.

Stem cells harvested from embryos rather than adults remain the most powerful for cloning and other purposes; Yang's team showed that cloning from such cells succeeded in 49 percent of attempts and led to 18 mouse pups.

In a new study the PhD students Jan Hoeber, Niclas König and Carl Trolle, working in Dr.Elena Kozlova's research group transplanted human stem cells to an avulsion injury in mice with the aim to restore a functional route for sensory information from peripheral tissues into the spinal cord.

Bone marrow mesenchymal stem cells and bone cells from the skulls of Cbf - beta - deficient mice showed increased expression of adipocyte genes.

Both groups isolated carefully characterized blood stem cells from genetically marked mice.

The paper doesn't include any genetic analysis of the final eggs that confirms they are healthy, notes Mitinori Saitou, a stem cell biologist at Kyoto University in Japan whose team developed methods to create mouse egg cells from embryonic or reprogrammed stem cells.

Starting in the mid-2000s, Yoshiki Sasai's team at the RIKEN Center for Developmental Biology in Kobe, Japan, demonstrated how to grow brainlike structures using embryonic stem cells, first from mice and then humans.

The scientists first compared mouse megakaryocyte cells created from embryonic stem cells engineered to lack p45 - Nfe2 with normal megakaryocytes.

Egg and sperm - like cells have recently been derived from animal stem cells, and this year the first mice were born from lab - grown sperm.

The team could isolate muscle stem cells from the male mice before they died and when they transplanted them into muscle - damaged recipient mice, they found that the stem cells were able to regenerate new muscle.

The researchers implanted stem cells from mouse embryos into the brains of rats and mice whose dopamine - producing neurons had been obliterated by a toxin.