Sentences with phrase «from noncoding»
Some of the transcripts hail from noncoding DNA, the researchers report, but those that do match up with the 399 ENCODE genes overlap with each other extensively.
https://www.scientificamerican.com/ Not exact matches
The researchers detected this SMN long noncoding RNA, or lnc - RNA (pronounced «link RNA») for short, in human embryonic kidney cells, brain cell samples and neurons derived from the stem cells of healthy people and those with spinal muscular atrophy type I and II.
The shadow cast has been so deep that a whole universe (or so it seems) of RNA — predominantly of the noncoding variety — has remained hidden from view, until recently.
In a series of elaborate experiments researchers from Harvard Medical School and Brigham and Women's Hospital discovered that mouse poop is chock full of tiny, noncoding RNAs called microRNAs from their gastrointestinal (GI) tracts and that these biomolecules appear to shape and regulate the microbiome.
«Molecular defenses spearheaded by small RNAs called piRNAs (my favorite noncoding RNAs) can keep transposons from jumping,» Saey says.
Researchers have ignored these noncoding RNAs until recently for not complying with the central dogma of biology — that a straight line runs from gene to RNA (transcription) to protein (translation).
One way to control expression, he explains, is through microRNA, small pieces of noncoding genetic material that control whether a gene's protein is generated from the DNA blueprints inside cell nuclei.
Spliceosomes, made from proteins and short, noncoding RNA fragments, carry out splicing via catalysis, which in biological processes is usually attributed to protein - based enzymes.
To provide a molecular basis for understanding N - CAM function, the complete amino acid sequences of the three major polypeptides of N - CAM and most of the noncoding sequences of their messenger RNA's were determined from the analysis of complementary DNA clones and were verified by amino acid sequences of selected CNBr fragments and proteolytic fragments.
They extracted and amplified DNA from these samples, concentrating on microsatellites, repetitive noncoding DNA sections that rapidly accumulate genetic changes.
This, in my opinion, is one of the most compelling parts of this study: in vivo functional validation of a single base change in a noncoding enhancer that's hundreds of thousands of bases away from the gene it regulates.
Huang Y - F, Gulko B, Siepel A. Fast, scalable prediction of deleterious noncoding variants from functional and population genomic data.
Messenger RNAs (mRNAs) that code for proteins and noncoding RNAs are key components in the transmission of genetic information in all life forms - from viruses to complex mammalian organisms.
A team of scientists from Whitehead Institute and other institutions has shown for the first time how two long intergenic noncoding RNAs (ncRNAs) in brewer's yeast (Saccharomyces cerevisiae) contribute to a location - dependent switch for the yeast FLO11 gene to toggle between active and inactive states.