Not exact matches
«A general message
from these studies is that cancer
cells benefit
from modulating epigenetic factors like SIRT6 by acquiring the ability to override
normal cellular
growth control patterns,» says Mostoslavsky, an associate professor of Medicine at Harvard Medical School and an associate member at the Broad Institute.
Inhibition of transcription (blockade of water) on tumor suppressor genes, such as p21, leads to
cell transformation (
growth of the cactus - like eremophytes instead of
normal plants
from the drought).
Experiments on mice and on heart
cells obtained
from infants born with congenital heart disease suggest that neuregulin 1, a human
growth factor, can put infant heart
cells on a path that mimics
normal growth rather than stalling out.
By matching
normal and cancer
cells from a patient, we can now study the differences — what molecules are key to tumor development and
growth, and, ultimately, match treatments that might disable this cancer,» says the study's senior investigator, associate professor of pathology, Xuefeng Liu, MD, a member of the Center for
Cell Reprogramming (CCR) at Georgetown University Medical Center.
Other
growth factors help
normal cells recover
from side effects of chemotherapy.
We've identified that ketone bodies, i.e. fuels in the bloodstream that result
from a very low carbohydrate diet, metabolically inhibit
growth of 7 cancer
cell lines in
cell culture, but not 3
normal cell types.
In
cell culture studies we published that ketone bodies (KB) inhibited
growth of 7 different cancers
from 20 - 50 %, leaving
normal cells unaffected.