Sentences with phrase «from normal cells»

As medical science advanced, it became increasingly likely that cancer cells differ from normal cells in ways that make them foreign in the eyes of the immune system.

Cancer cells differ from normal cells in the profile of their gene expression.

Once the cells have changed from a normal cell to a nitrogen - fixing one there is no going back and they become totally dependent on the other cells for energy.

In the bloodstream, circulating tumor DNA is only a small subset of the total cell - free DNA, as most circulating fragments of genetic material come from normal cells.

Cancer cells may produce unique metabolic profiles, in part because they grow very rapidly and have metabolic activity very different from normal cells.

But a clone develops from the nuclear DNA taken from a normal cell in an adult animal.

By comparing this data to similar information from normal cells, he can figure out how and why things go wrong in cancer.

The goal is to make and receive calls directly from your normal cell but with a different phone number — without having to pay for another phone.

Senescent cells originate from normal cells of our body that irreversibly cease to proliferate in response to DNA damage.

Due to either or both tumor heterogeneity and / or normal contamination (presence of DNA from normal cells in the tumor sample), coverage levels may not correspond to integer - valued ploidy.

Importantly, it's secretion from normal cells can be induced by activating p53 so that Par - 4 enters circulation, thereby potentially targeting tumor cells at distant sites.

When cancer cells proliferate, they appear to need the help of a protein called survivin: The protein is abundant in cancer cells but almost absent from normal cells.

And not only cancer: «Tyrosine phosphorylation is now known to be involved in a large number of absolutely crucial cellular functions from normal cell growth to intracellular vesicle trafficking to immune responses.

For the first time, researchers have discovered that some leukemia cells harvest energy resources from normal cells during chemotherapy, helping the cancer cells not only to survive, but actually thrive, after treatment.

NKG2D is a type of immunoreceptor — a molecule present on the surface of the body's immune cells that recognises signals from normal cells that are distressed.

Stern's aim was to define how cervical cells change during cancer progression, and if dysplasia was a step in this process from normal cell to malignant tumor.

We observed that exosomes from glaucomatous lamina cribrosa cells were different than exosomes from normal cells.

This is because tumor - derived and immortalized cells are often karyotypically abnormal and may diverge physiologically from normal cells in various respects, whereas primary cells have limited capacity for expansion.

PV - 10 (rose bengal disodium 10 %), a small - molecule fluorescein derivative, while excluded from normal cells, transits the plasmalemma of cancer cells and accumulates in lysosomes, triggering lysosomal release and complete autolysis within 30 to 60 minutes.

Each malfunction sets the cancer cell apart from the normal cell; each may be a keystone for the creation of a therapeutic magic bullet.

However, the immune system has a harder time identifying cancer cells as foreign, sometimes due to the fact that they don't appear different enough from normal cells or the immune system isn't powerful enough to take on the cancer.

Cancer cells steal from normal cells not only glucose but nutrients as well.

Lifespan following the discovery of a malignant mammary tumor depends on many things such as the type of tissue involved (ducts or connective tissue in the breast), the grade of the tumor (how dissimilar the tumor cells are from normal cells when viewed under a microscope), the tumor size (smaller than 3 cm is best), and the tumor stage (whether or not there are metastases and where they are located — regionally or scattered throughout the body).

Using this technique, scientists could classify the thousands of different types of cells in the brain, map how they connect to each other, and figure out how diseased cells differ from normal cells.

«Tissues with higher turnover rates are typically more susceptible to cancer development simply because there are more opportunities for errors to accumulate and force the change from a normal cell to a malignant one,» Shen said.

For every 100 DNA fragments, only one may come from the tumor, and the rest may come from normal cells, mainly bone marrow cells,» said Dr. Razavi.

Without this approach, the results of genomic sequencing would have been swamped with DNA from normal cells, making it difficult to detect cancer - linked DNA errors, Papp says.

The nanosensor amplifies pH signals in tumor cells to more accurately distinguish them from normal cells.

By interfacing brain cells onto graphene, researchers at the University of Illinois at Chicago have shown they can differentiate a single hyperactive cancerous cell from a normal cell, pointing the way to developing a simple, noninvasive tool for early cancer diagnosis.

Once they identified the cancer cells, the researchers were able to separate them from normal cells.

In effect, Affigen uses cancer's «Achille's Heel»: the proteins which distinguish tumor cells from normal cells, that can target tumor cells for destruction with extreme sensitivity and precision.

Interestingly, alterations in these un-druggable genes distinguish cancer cells from normal cells, conferring «synthetic lethal» vulnerabilities that can be exploited by novel targeted therapies.

The Innovation Fund award will support a pilot study in which cells from the cerebrospinal fluid of MS patients will be genome sequenced to determine how they differ from normal cells.

This will help us better understand how a diseased cell differs from a normal cell, which will enhance our understanding of the pathways of various diseases.»