Sentences with phrase «from normal mice into»

Faustman got her idea by chance while transplanting islets, the pancreatic bodies that contain beta cells, from normal mice into others that had lost theirs to type 1, or juvenile, diabetes.

To see whether it was a true functional organ, his team transplanted the small thymus from normal mice into mutant, thymus - free animals.

Not exact matches

The behavioral tests used here modeled one dimension of the disease — an inability to experience pleasure from normal activities — but not others, such as stress and anxiety, and probably tap into different brain mechanisms in mice than in humans, he says.

Her team took purified extracts of the miRNA from stressed mice and injected them into normal embryos.

They expected eggs to be more complex, but last year, Hayashi made PGCs in vitro with cells from a mouse with normal coloring and then transferred them into the ovaries of an albino mouse.

During her postdoctoral work, Bissell noticed that removing mammary cells from a mouse and putting them into a culture dish caused them to lose not only their normal in vivo shapes, but also their ability to secrete milk.

In an independent effort, they introduced progressively smaller pieces of DNA from the large region known to contain the gene into embryos of the mutant mice, looking for the smallest piece that would correct the mutation in adult mice and restore a normal rhythm.

In the latest study, the researchers injected the nine miRNAs into zygotes from normal mice, implanted the zygotes in females, and allowed them to mature.

Kipnis and his colleagues wondered how smart mice would be if they had a normal supply of T cells everywhere in their bodies except the meninges, so he injected a compound into mice that prevented T cells from reaching the meninges.

For the first time, researchers have been able to grow, in a lab, both normal and primary cancerous prostate cells from a patient, and then implant a million of the cancer cells into a mouse to track how the tumor progresses.

When bacteria from these «clockless» mice were transplanted into healthy animals living in normal light - dark conditions, the microbes began to show normal rhythms within a week.

This decrease in circulating miRNAs could be restored when the investigators transplanted normal fat into these mice, a result indicating that many of the microRNAs in circulation were coming from fat.

Constructs lacking the RP sequence were barred from the mitochondria, and even constructs with appended RP were reduced to ~ 13 - 17 % of normal import into mitochondria from mice with a liver - specific, two - thirds reduction in levels of the murine PNPase homolog.

Cells with normal karyotype were injected into blastocysts isolated from C57BL / 6 mice.