Sentences with phrase «from other animal models»

However, data from other animal models demonstrate diminished lysosomal enzyme activity during extended periods of energy restriction (39).

Not exact matches

«Gene - delivery system prevents vision loss from inherited eye disease: Initial testing in animal models holds promise for treating Leber congenital amauroisis and other congenital visual disorders.»

New research from McLean Hospital neuroscientists shows in an animal model that being bullied can have long - term, dramatic effects on sleep and other circadian rhythm - related functions, symptoms that are characteristic of clinical depression and other stress - induced mental illnesses.

Importantly, the development of a new animal model for Dravet syndrome based on reduced CHD2 expression might help to find effective treatments that could improve the lives of thousands of people suffering from Dravet syndrome and perhaps other genetic epilepsies.»

And the trouble with extrapolating so much from mouse studies is that «nobody has actually shown over the long term how long these quote un-quote improvements persist, and we don't know whether it's broadly improving aspects of aging or it's specific to certain tissues,» said Matt Kaeberlein, a biologist who studies aging in dogs and other animal models at the University of Washington.

But this remarkable therapeutic benefit isn't limited to MS. Previous research in animal models that mimic other diseases suggest that certain forms of amyloids can ease damage from strokes, traumatic brain injuries and even heart attacks.

The BUSM researchers believe the data from this study and those reported by others in animal models as well in clinical studies strongly suggest that Avodart may have serious adverse side effects that were not obvious several years ago.

In the end, three companies formed to try to exploit CRISPR to create novel medicines, while Broad and two other companies licensed the technology to partners that hoped to engineer everything from improved crops and livestock to better animal models and industrial chemicals.

The decision follows recommendations from an NIH advisory panel that said in January that the agency should curb research on chimps and instead «emphasize the development and refinement of other approaches, especially alternative animal models,» and move all but approximately 50 of the chimps to sanctuaries.

Using a mathematical model that combines a huge number of cattle and badgers that have TB, the researchers were able to quantify the relationship between the two animals and use a big data approach to show that the route of infection for cattle is from other cattle rather than from other species.

«We know from animal models that there are critical periods during early development when cells are rapidly dividing and forming the circuitry through which cells will communicate with each other to form various tissues of the body,» said Retha Newbold, a reproductive biologist at the National Institute of Environmental Health Sciences in North Carolina.

«You can not really test the idea that animal reservoirs are important other than building a model from the data available.

We have learned a fair amount from the neurologic genetic diseases, but we and others also studied these cells in the laboratory as well as in animal models of brain injury.

Moreover, we were able to recapitulate toxicity findings from the clinic that were not previously observed in other in vitro systems or predicted by animal models.

Both recent experience with immunotherapy for clearance of Aβ in AD, and their own (and Prothena's) experience with AS - clearing immunotherapies in animal models, indicate that in order to be effective as disease - modifying agents when administered alone, therapies that remove proteinaceous aggregates from the brain must be initiated in the early clinical or even preclinical stages of the disease, before the burden of other forms of aging damage becomes entrenched.

Additional protocols are currently under development to measure SMN protein in other tissues and biofluids, as well as in various tissues from animal models.

She also speculates that interspecies transmission of microbes — from dogs to humans, say, or the other way around — could affect interspecies altruism, another prediction that could be tested using animal models.

Future models, it seems, will come in many varieties, ranging from several kinds of animals to in vitro systems to computers, with each approach building on the others.

After discussing similar effects in other animal models of cancer and a few studies showing the ability of antioxidants to prevent cancer growth, Campbell concluded that «a pattern was beginning to emerge: nutrients from animal foods increased tumor development while nutrients from plant - based foods decreased tumor development.»

Aside from antioxidant mechanisms (stabilizing free radicals that would normally damage lipid membranes and microcirculation), vitamin C can help normalize pain - inhibiting pathways involving dopamine, NMDA, and other neurotransmitters, and has shown promise for a variety of pain conditions in animal models.

Emerging evidence from animal models and clinical trials suggest keto may be therapeutically used in many other neurological disorders, including head ache, neurodegenerative diseases, sleep disorders, bipolar disorder, autism and brain cancer.

If we equate de facto ketogenic diets with high - protein diets (which is not always correct) then the risks proposed by critics of this type of dietary approach are essentially those of possible kidney damage due to high levels of nitrogen excretion during protein metabolism, which can cause an increase in glomerular pressure and hyperfiltration.12 There is not wide agreement between studies; however, some infer the possibility of renal damage from animal studies, 99, 100 whereas others, looking at both animal models, meta - analyses and human studies, propose that even high levels of protein in the diet do not damage renal function.101, 102 In subjects with intact renal function, higher dietary protein levels caused some functional and morphological adaptations without negative effects.103 There may actually be renal - related effects, but on blood pressure rather than morphological damage.

Several charming models, from superb high - top sneakers, cool slip - ons, flat espadrilles, classic derbies, and loafers to the most sporty glam boots and other fashionable footwear embellished with spikes or studs, strass, metallic animal prints and other signature details of the house in trendy, modern colors.

«THE IFAW LIFETIME DEDICATION AWARD GOES TO CELIA HAMMOND - One of the top models in the 60's appearing on countless Vogue covers, Celia used her modelling career as a platform from which to campaign against the fur trade, factory farming, vivisection, and other animal abuses.

This resulted in a lot of publicity and Celia realised that her modelling career gave her an ideal platform from which to campaign against the fur trade, factory farming, vivisection, and other animal abuses including, much later, the live export of sheep, calves and pigs across Europe from the UK.

Drawing from everyday events and characters, he tells stories of pathetic men (often modeled after himself), randy old men chasing exceptionally voluptuous women, and other odd characters including gurus, seers and talking animals.

Opening: «Eduardo Sarabia: Ballads» at Other Criteria Combining decorative art objects with motifs referencing the Mexican and Mexican - American drug scene — ranging from guns, skulls, and nude pin - up models to marijuana leaves and animals symbolizing specific illegal drugs — Eduardo Sarabia makes art from Narco culture.