Sentences with phrase «from other tumor»

It is important to differentiate osteosarcoma from other tumor types and diseases that occur within bones, such as bacterial, viral, or fungal infections.

Not exact matches

The institute's Tumor Neoantigen Selection Alliance, which includes Bhardwaj's team and others from the University of Pennsylvania and to Stanford Medicine, is focusing on discovering «cancer markers» and then making predictions on neoantigens to combat them.

In Silt, Colorado, a woman named Laura Amos no longer talks about the adrenal - gland tumor and other health complications she developed after her water was contaminated by a gas well drilled less than 1,000 feet from her home.

The Kamens claim the main thing that distinguishes their foundation from other brain tumor foundations is their focus on pediatric brain cancer specifically, as well as their close ties with pharmaceutical and biotech companies working in the fields of immunotherapy and target gene therapy.

Breast lump removal is performed to prevent a cancerous tumor from spreading to other parts of your body.

I am unsure why you disagree with using data / results from studying other animals that are known to be similar to humans — I see studies all the time that correlate results in other species (eg, to demonstrate the carcinogenic properties of something, they give it to rats and watch for tumors).

The focus of those hopes is the liquid biopsy: a test that could detect and analyze a solid tumor from biomarkers in the bloodstream or other easily sampled body fluids, such as saliva.

Breast cancer tumors can fuse with blood vessel cells, allowing clumps of cancer cells to break away from the main tumor and ride the bloodstream to other locations in the body, suggests preliminary research.

EphA2 spreads cancer by allowing malignant cells to migrate from the primary tumor into circulation and eventually to adhere to other tissues.

That includes going after notoriously deadly metastatic tumors — ones that have spread from other parts of the body.

The immune system depends on molecules called T cell receptors on the surface of T cells to recognize and respond to foreign antigens from virus - infected cells, tumors and other threats.

Avastin, from Genentech, and Erbitux, from ImClone Systems, are the first drugs to reduce tumor growth from colon cancer that has spread to other parts of the body.

«We are looking for novel ways of preventing cancer cells of the primary tumor from spreading to other parts of the body.

The study published in Cancer Cell shows that exosomes from tumor cells of breast cancer (and other tumor types such as ovarian and endometrial) are different in size and composition than those of healthy cells.

Cells suspended in a stiff matrix were more likely to work their way through the matrix to other side of a serum gradient, analogous to how metastasizing cancer cells break free from their tumors.

«This helps us distinguish malignant from healthy tissue and tells us how the tumor is responding to chemotherapy earlier than other imaging techniques can.»

These devils are suffering from a malady so odd many researchers scarcely thought it possible: One devil's cancer has learned how to survive in other devils» bodies, and that one tumor is now threatening to wipe out an entire species.

And in at least a few lab - reared fish, UV can initiate the development of melanoma (especially among hybrids which inherit a tumor - promoting gene from one parent but no accompanying tumor - suppressor gene from the other).

Instead, researchers told the European Breast Cancer Conference that their findings suggest that extending screening programs to older women results in a large proportion of women being over-treated, and at risk from the harmful effects of such treatment, because these women were more likely to die from other causes than from any tumors detected in the early stages of growth.

Using tumor biopsies from BRAF melanoma patients treated with either BRAF inhibitors or with combined BRAF and MEK inhibitors, a recently FDA - approved drug combination to fight the other mechanisms of resistance, the researchers found that tumors resistant to the BRAF inhibitors had increased levels of autophagy compared with baseline tumors.

A team under Professor Scheffler, consisting of researchers from the Bonn University Hospital, the Life & Brain Center, The German Consortium for Translational Cancer Research, Tufts University Boston / Massachusetts, and other institutes in the USA, has now developed a new method that is expected to combat such complex brain tumors better.

By linking these layers and others to expand from genomics to multi-omics, scientists might be able to meet the goals of personalized medicine: to figure out, for example, what treatment a particular cancer patient will best respond to, based on the network dynamics responsible for a tumor.

It is well established that melanoma cells can spread through the blood to accumulate and form new tumors (metastases) in other parts of the body away from the original tumor.

«Nobody ever looked for NPTX2 as a potential tumor promoter in kidney cancer or any other cancer, from what we can tell,» says Dr. Radisky.

The primary cause of death from breast cancer is the spread of tumor cells from the breast to other organs in the body.

But the cells also changed shape and other properties in the absence of the protein in ways that reduced the likelihood that they would travel away from the tumor — a sign that myoferlin not only changes genes in cancer cells, but also alters the cells» mechanical properties.

The team chose to compare breast tissue from healthy individuals with tumor samples taken from breast cancer patients — including both primary tumors that had not spread from the breast to other body sites, and highly aggressive, metastatic tumors.

Metastasis (the spread of cancer from its primary site to other places in the body) to the ovaries can result in Krukenberg tumors.

Unlike other solid tumors, there has been limited progress in understanding the contribution of genetic risk factors to the development of uveal melanoma, researchers say, primarily due to the absence of comprehensive genetic data from patients as the large sample cohorts for this rare cancer type have not been available for research.

In order to identify the cancer stem cells from other cells in the tumor, the research team studied epigenetic mechanisms that distinguish between the least - sorted cells, with endless division properties and a potential to create growth, and the more sorted cells which lack this ability.

Over the past two years Skinner, of Washington State University, showed that as male descendants of these rats aged, they developed sperm deficiencies, infertility, and various other afflictions, from breast tumors to kidney disease.

«Tumors collected from devils subjected to the removal programme showed accelerated temporal evolution of tetraploidy compared with tumors from other populations where no increase of tetraploid tumors were observed.&Tumors collected from devils subjected to the removal programme showed accelerated temporal evolution of tetraploidy compared with tumors from other populations where no increase of tetraploid tumors were observed.&tumors from other populations where no increase of tetraploid tumors were observed.&tumors were observed.»

Research from other scientists at Johns Hopkins, he says, had suggested that some tumors, particularly those that affect the nervous system, have mutations in the ATRX gene, which produces proteins that appear to maintain the length of telomeres, repetitive segments of DNA on the ends of chromosomes that typically shorten each time a cell divides.

And if fetal cells protect women from breast cancer, they might also safeguard against other tumors.

The Nakano lab is also working on brain metastases, tumors that spread into the brain from other parts of the body.

This allows cancer cells to break off from tumors, spread throughout the body (in blood or other fluid) and form new tumors at distant sites — a process called metastasis.

The investigators also identified instances in which the genetic profiles of metastases were similar to those of only some cells in the primary tumor, suggesting that those cells were the source of the metastases, and other cases in which the genetic profiles of metastases from the same primary differed depending on their location.

The cell changes, known as an epithelial to mesenchymal transition, or EMT, are normal and helpful during wound healing, but problematic when cancer cells spread from the primary tumor site to other sites in the body.

Analyzing the poly - G profiles of primary and metastatic colon cancer samples from 22 patients revealed that how the primary and metastatic tumors related to each other was different for each patient.

The researchers are now further investigating the possibility of using this approach on other cancers, including prostate cancer, where it could be used to distinguish more aggressive tumors from those that grow much more slowly, Bhatia says.

Previous in vitro studies conducted by researchers in other countries showed that this molecule was able to reduce the multiplication and increase the mortality of cells from melanoma, the most aggressive type of skin cancer, as well as breast cancer and neuroblastoma, a tumor that typically affects patients aged 15 or younger.

Using cultured cells derived from human tumors of the breast and prostate gland, they confirmed that the IL6R / STAT3 / miR -34 a feedback loop is also activated in other tumor types.

From 2000 - 2013, the number of reported MCC cases increased 95 percent, compared to 57 percent for melanoma and 15 percent for other cancerous tumors.

At the same time, other switches get flipped throughout the body, modifying everything from metabolism to cell growth, via other cytokines, such as IL - 6 and tumor necrosis factor — a, and things like CRP, which mark bacteria for destruction.

The final list of 24 questions ranges from how obesity contributes to cancer risk, to why certain mutations promote cancer in some tissues but not others and why some tumors lie dormant for years before becoming malignant.

To search for other characteristics of ccRCC tumors that influences immunotherapy response or resistance, the researchers used whole - exome DNA sequencing to analyze tumor samples from 35 patients treated in a clinical trial with the checkpoint blocker nivolumab (Opdivo).

So, for example, at the University of California in San Francisco they are trying to engineer E. coli so that it can detect cancer cells, it can invade tumors, and then once it's inside they can release toxins; and so they are putting in all sorts of genes from other bacteria to assemble this, you know, this sort of synthetic E. coli that could become basically a cancer torpedo.

Their latest pledge came after Druker recently lobbied the couple for another $ 1 billion to take insights from Gleevec, as well as other so - called molecularly targeted therapies, and develop better early detection tools for tumors.

The team's experiments in cell cultures, conducted with funding from an American Brain Tumor Association Discovery Grant, showed that coibamide A cuts off the cancer cells» ability to communicate with blood vessels and other cells, eventually starving the cell and triggering its death.

«We note that there are two subgroups of breast tumors by epigenome: one which we have called Epi - Basal, characterized by loss of epigenetic marks causing breakage of chromosomes and the other that we have called Epi - Luminal B, that presents epigenetic inactivation of genes that should protect us from cancer and these altered cells can no longer do it.»