Sentences with phrase «from rodent models»

From rodent models, the approach / avoidance theory of maternal behaviour suggests that neuroendocrine changes associated with parturition trigger a reduction in the aversive response of mothers towards pups while simultaneously provoking approach behaviours.

«Much of this information currently comes from rodent models and small clinical trials but the evidence is encouraging.»

T - tubules of isolated cardiomyocytes from rodent models of cardiac diseases are labelled using fluorescent dextran that diffuses from extracellular space to TATS lumen.

Using neurons extracted from rodent models of Huntington's, the team employed the OPL method, which tracked the speed and efficiency with which different types of neurons were able to break down and dissolve the mutant huntingtin.

Not exact matches

Early adverse experience as a developmental risk factor for later psychopathology: evidence from rodent and primate models.

p11 is increased in rodent brains by antidepressants or electroconvulsive therapy, but decreased in an animal model of depression and in brain tissue from depressed patients.

Unlike rodent models, which are developed from inbred strains of mice kept in controlled environments, companion animals, like humans, are genetically diverse and are exposed to many of the same environmental influences as their owners are.

Dr Kristensen recommends that an inter-disciplinary approach be taken to address this, «by combining epidemiological data from human studies with more experimental research on models, such as rodents, it may be possible to firmly establish this link and determine how it happens, so that pregnant women in pain can be successfully treated, without risk to their unborn children.»

Yu then worked with another researcher from the Academy of Military Medical Sciences to test a crude extract of qinghao on a rodent model of malaria, finding that the extract killed parasites with 60 % to 80 % potency.

The discovery in a rodent model may provide insight into what happens in the visual systems of children born with a condition that prevents the optic nerve from fully developing.

We hypothesized that brain activity associated with threat detection and distal and proximal distance to threat in humans would mirror those derived from defense systems models developed in rodents.

Previous research in rodent disease models has shown that transplanted oligodendrocyte precursor cells derived from embryonic stem cells and from human fetal brain tissue can successfully create myelin sheaths around nerve cells, sometimes leading to dramatic improvements in symptoms.

Currently, the human health risk from exposure to a given endocrine disruptor is normally assessed using a rodent model.

Data from leptin - deficient rodent models have revealed regionally specific effects on the skeleton, with reports of cortical bone atrophy in weight - bearing long bones like the femur and tibia (11 — 16).

So the team engineered a mouse model that gradually lost the enzyme as it grew older and then bred those mice with rodents that were engineered to develop amyloid plaques from an age of 75 days.

In other places the authors extrapolate inappropriately from data on rodent models or data relating to different health outcomes (e.g. cancer).

Intrastriatal Transplantation of Adenovirus - Generated Induced Pluripotent Stem Cells for Treating Neuropathological and Functional Deficits in a Rodent Model of Huntington's Disease» from Stem Cell Translational Medicine by Stuart P. Atkinson.

Review of «Intrastriatal Transplantation of Adenovirus - Generated Induced Pluripotent Stem Cells for Treating Neuropathological and Functional Deficits in a Rodent Model of Huntington's Disease» from Stem Cell Translational Medicine by Stuart P. Atkinson.

Title: Spontaneous object recognition and its relevance to schizophrenia: a review of findings from pharmacological, genetic, lesion and developmental rodent models Author: L. Lyon et al..

Diet - Induced Metabolic Syndrome in Rodent Models - An article from the March 2007 issue of Animal Lab News on how diets made from purified ingredients influence the phenotypes of the MS in commonly used rodent models, authored by our scienRodent Models - An article from the March 2007 issue of Animal Lab News on how diets made from purified ingredients influence the phenotypes of the MS in commonly used rodent models, authored by our scienModels - An article from the March 2007 issue of Animal Lab News on how diets made from purified ingredients influence the phenotypes of the MS in commonly used rodent models, authored by our scienrodent models, authored by our scienmodels, authored by our scientists.

Transgenic models session Chairs V.Korinek & Z. Kozmik 16.00 Bohumil Fafílek Cell tracking and manipulation in genetically modified mice 16.30 Michaela Krausová Mouse transgenic model to study tumor progression and metastasis in the gut 17.00 coffee break 17.20 Matej Durik Rodent transgenic models of cardiovascular diseases 17.50 Jan Masek The role of Wnt / beta - catenin signaling in neural crest development: an insight from transgenic and knockout mice 19.00 dinner

The results were obtained from mice and human stem cells in cultivated brain tissue, and from a series of rodent models for human neurodegenerative diseases and acute brain injuries.

In mouse models in which the endogenous Smn1 gene has been knocked out and human versions of SMN2 have been swapped in, the Isis therapy — a so - called «antisense oligonucleotide» — delivered to the mouse central nervous system (CNS) increased the expression of full - length SMN protein in motor neurons, improved muscle strength in behavioral tests and extended the rodents» median lifespan from 16 days to 26 days3.

(3) In this brief review, we discuss how diets made from purified ingredients influence the phenotypes of the MS in commonly used rodent models.

Chia - Shan Wu, Carlos J. Ballester Rosado, Hui - Chen Lu (2011) «What can we get from «BARRELs» - the rodent barrel cortex as a model to study the establishment of neural circuits», European J. Neuroscience, 34:1663 - 76.

A discussion of how diets made from purified ingredients influence the phenotypes of the MS in commonly used rodent models.

She will discuss the Systems Biology approaches currently used to understand the Omics results from space flight model systems (rodent, fruit fly etc) in the context of tissue response (i.e. muscle, liver, other vital organs).

Three animal studies from Allen Taylor and his colleagues at Tufts University compared the effects of resistant starch versus highly digestible starch on eye health in rodent models.

We provide evidence for a causal link between the early caregiving environment and stress response system reactivity in humans with effects that differ markedly from those observed in rodent models.

In rodent models that focus on understanding functional impairment, prolonged separation of neonates from their mother leads to long - term deficits relative to controls (1 — 3).